Gene Information gene info

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GENE：THBD

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol THBD
FullNmae thrombomodulin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11784
EnsembleID ENSG00000178726
Uniprot P07204

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
THBD immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
THBD autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
THBD GO:0004888,GO:0005509,GO:0005515,GO:0005615,GO:0005774,GO:0005886,GO:0006508,GO:0007565,GO:0007596,GO:0009897,GO:0009986,GO:0010165,GO:0010544,GO:0016327,GO:0030195,GO:0030195,GO:0031638,GO:0032496,GO:0038023,GO:0051591,GO:0051918,GO:0072377,GO:1905370

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
THBD hsa:7056 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)
THBD hsa:7056 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
THBD hsa:7056 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ELAVL1 THBD 18579691 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 THBD 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SP1 THBD 11036068 22406829 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
SMARCA4 THBD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF THBD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 THBD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 THBD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EP300 THBD 15677570 trascriptional regulation,stimulation inferred by curator TFlink
KLF2 THBD 19661484 trascriptional regulation,stimulation inferred by curator TFlink
KLF4 THBD 19661484 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 THBD 17211835 22406829 trascriptional regulation,stimulation inferred by curator TFlink
PARP1 THBD 21489980 trascriptional regulation,stimulation inferred by curator TFlink
RARA THBD 11036068 9269772 trascriptional regulation,stimulation inferred by curator TFlink
RARB THBD 11036068 trascriptional regulation,stimulation inferred by curator TFlink
RARG THBD 11036068 trascriptional regulation,stimulation inferred by curator TFlink
RELA THBD 17211835 22406829 trascriptional regulation,stimulation inferred by curator TFlink
RXRA THBD 11036068 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 THBD 11036068 22406829 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 THBD N/A trascriptional regulation,stimulation inferred by curator TFlink
ETS2 THBD N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 THBD 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 THBD 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 THBD 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000170D8B THBD 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PF4 THBD 25361965 interaction type N/A PTMCode2
THBD PF4 25361965 interaction type N/A PTMCode2
F2 THBD 25361965 interaction type N/A PTMCode2
THBD F2 25361965 interaction type N/A PTMCode2
PROC THBD 25361965 interaction type N/A PTMCode2
THBD PROC 25361965 interaction type N/A PTMCode2
SERPINA5 THBD 25361965 interaction type N/A PTMCode2
THBD SERPINA5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LMNA THBD 25348397 N/A physical interaction ComPPI
F2 THBD 14525934 14691232 24234451 25348397 7615164 8663147 N/A experimental interaction detection,surface plasmon resonance,physical interaction,in vitro,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
PROC THBD 11106601 12588872 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SERPINA5 THBD 12878585 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PF4 THBD 14525934 25348397 9395524 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
THBD PSENEN 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
THBD CYBC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD ERGIC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD SLC19A3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD MMGT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD PHF24 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD CIDEB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD GPX8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD TMEM14B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD TMEM35A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD PDZK1IP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD CD79A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD APOC4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD FAM209A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD AQP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THBD EBP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTIF3 THBD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TMEM86B THBD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HMGB1 THBD 15841214 27898060 N/A N/A OmniPath
PF4 THBD 27898060 9395524 stimulant N/A OmniPath
PROCR THBD 27898060 9395524 N/A N/A OmniPath

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