Gene Information gene info

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GENE：UNG

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UNG
FullNmae uracil DNA glycosylase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12572
EnsembleID ENSG00000076248
Uniprot P13051

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UNG mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UNG autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UNG GO:0003684,GO:0004844,GO:0004844,GO:0004844,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005739,GO:0005739,GO:0006281,GO:0006284,GO:0016446,GO:0043024,GO:0043066,GO:0045008,GO:0045190,GO:0097510,GO:0097510

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UNG hsa:7374 path:hsa03410 Base excision repair - Homo sapiens (human)
UNG hsa:7374 path:hsa05340 Primary immunodeficiency - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP UNG 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 UNG 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 UNG 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 UNG 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 UNG 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 UNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 UNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF UNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 UNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 UNG N/A trascriptional regulation,stimulation inferred by curator TFlink
SP1 UNG N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002C7B2B UNG 23228472 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00002C7B2B UNG 23228472 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000F31F4 UNG 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 UNG 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000048F59D UNG 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001799A3 UNG 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00007455B8 UNG 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D UNG 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 UNG 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB UNG 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 UNG 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005D35D9 UNG 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001A6D0C UNG 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF UNG 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000072E4C UNG 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000192A75 UNG 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F UNG 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 UNG 22135298 phosphorylation N/A PhosphoSite
GSK3B UNG 22135298 phosphorylation N/A PhosphoSite
CDK2 UNG 22135298 phosphorylation N/A PhosphoSite
GSK3A UNG 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
PCNA UNG 10393198 12171929 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
POLB UNG 25348397 N/A physical interaction ComPPI
H2BC4 UNG 25348397 N/A physical interaction ComPPI
UBE2E2 UNG 25348397 N/A physical interaction ComPPI
RPA1 UNG 25348397 N/A physical interaction ComPPI
PPP2CA UNG 25348397 N/A physical interaction ComPPI
RPA2 UNG 10393198 10872450 10982866 14525934 16189514 24234451 24332808 24910198 25348397 27898060 9045683 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,nuclear magnetic resonance,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
RPA3 UNG 25348397 N/A physical interaction ComPPI
UNG DDB1 25348397 N/A physical interaction ComPPI
UNG DCAF1 25348397 N/A physical interaction ComPPI
UNG HSPB1 25348397 N/A physical interaction ComPPI
UNG APP 25348397 N/A physical interaction ComPPI
UNG SMUG1 25348397 N/A physical interaction ComPPI
UNG THOP1 25348397 N/A physical interaction ComPPI
UNG SEZ6L2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UNG CAPN11 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UNG H2BC11 25348397 N/A physical interaction ComPPI
UNG CAMK2D 25348397 N/A physical interaction ComPPI
UNG STYX 25348397 N/A physical interaction ComPPI
UNG PPP2R2D 24234451 25348397 28330616 association pull down ComPPI,IntAct
H3C1 UNG 25348397 N/A physical interaction ComPPI
PPM1D UNG 15327777 15870257 16189514 27898060 inhibition N/A OmniPath
CDK1 UNG 18079698 27898060 N/A N/A OmniPath
GSK3B UNG 15327777 27898060 N/A N/A OmniPath

Visualization










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