Gene Information gene info

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GENE：USP18

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol USP18
FullNmae ubiquitin specific peptidase 18
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12616
EnsembleID ENSG00000184979
Uniprot Q9UMW8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
USP18 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
USP18 GO:0004843,GO:0004843,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005829,GO:0005829,GO:0005829,GO:0006508,GO:0009617,GO:0016579,GO:0019785,GO:0035634,GO:0043231,GO:0050727,GO:0060090,GO:0060339,GO:0140374

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
USP18 POLR2F 23180781 23994473 physical association anti tag coimmunoprecipitation InnateDB
MAP3K7 USP18 23825189 24243840 29145629 physical association inferred by curator Reactome

Source Target Pmid Interactiontype Methods Database
ETS1 USP18 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 USP18 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 USP18 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 USP18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF USP18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 USP18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 USP18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS USP18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 USP18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A USP18 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000170CF4 USP18 20018759 rna interference,inhibition array technology,experimental interaction detection miRSponge
URS0000170CF4 USP18 20018759 25416803 mrna cleavage,inhibition array technology,experimental interaction detection TarBase
URS00000F31F4 USP18 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 USP18 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 USP18 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
SGTA USP18 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
ISG15 USP18 14525934 16189514 24234451 25307056 25348397 25416956 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
PCNA USP18 25348397 N/A physical interaction ComPPI
NUDCD3 USP18 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
BCL2L1 USP18 25348397 N/A physical interaction ComPPI
TMEM14A USP18 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBB USP18 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
UBC USP18 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
RPS27A USP18 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
UBA52 USP18 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
HERC1 USP18 25348397 N/A physical interaction ComPPI
STIP1 USP18 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
IKBKB USP18 25348397 N/A physical interaction ComPPI
NME1 USP18 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CACYBP USP18 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
ZDHHC17 USP18 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SKP2 USP18 25348397 N/A anti bait coimmunoprecipitation,physical interaction,physical interaction ComPPI
TTC1 USP18 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
CHUK USP18 25348397 N/A physical interaction ComPPI
MAP3K7 USP18 25348397 N/A physical interaction ComPPI
TAB2 USP18 25348397 N/A physical interaction ComPPI
BECN1 USP18 25348397 N/A physical interaction ComPPI
PIK3C3 USP18 25348397 N/A physical interaction ComPPI
CARD11 USP18 25348397 N/A physical interaction ComPPI
TRIM54 USP18 25348397 N/A physical interaction ComPPI
MYL6 USP18 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP18 KDM3B 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP18 USP41 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP18 IFNAR2 14525934 16710296 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
USP18 MOV10 25348397 N/A physical interaction ComPPI
USP18 NXF1 25348397 N/A physical interaction ComPPI
USP18 ATG14 25348397 N/A physical interaction ComPPI
USP18 UVRAG 25348397 N/A physical interaction ComPPI
USP18 TAB1 25348397 N/A physical interaction ComPPI
USP18 IKBKG 14743216 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
USP18 STING1 25348397 N/A physical interaction ComPPI
USP18 FKBP5 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
USP18 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
FKBPL USP18 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct

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