Gene Information gene info

  1. Home

GENE：FGFR4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FGFR4
FullNmae fibroblast growth factor receptor 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3691
EnsembleID ENSG00000160867
Uniprot P22455

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FGFR4 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FGFR4 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FGFR4 GO:0005007,GO:0005007,GO:0005007,GO:0005515,GO:0005524,GO:0005576,GO:0005768,GO:0005783,GO:0005794,GO:0005886,GO:0005886,GO:0005911,GO:0007169,GO:0007275,GO:0008201,GO:0008284,GO:0008284,GO:0008543,GO:0008543,GO:0008543,GO:0010628,GO:0010715,GO:0016477,GO:0017134,GO:0017134,GO:0017134,GO:0018108,GO:0019216,GO:0030133,GO:0033674,GO:0042593,GO:0042632,GO:0043085,GO:0043235,GO:0045862,GO:0046777,GO:0055062,GO:0070374,GO:0070374,GO:0070857,GO:0070857,GO:2000573

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FGFR4 hsa:2264 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
FGFR4 hsa:2264 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
FGFR4 hsa:2264 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
FGFR4 hsa:2264 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
FGFR4 hsa:2264 path:hsa04144 Endocytosis - Homo sapiens (human)
FGFR4 hsa:2264 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
FGFR4 hsa:2264 path:hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)
FGFR4 hsa:2264 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
FGFR4 hsa:2264 path:hsa05200 Pathways in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
B3DJ84 FGFR4 20802085 N/A N/A SignaFish
KDRL FGFR4 20802085 N/A N/A SignaFish
FGF17 FGFR4 17081981 stimulation N/A SignaFish

Source Target Pmid Interactiontype Methods Database
MYC FGFR4 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 FGFR4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C FGFR4 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA FGFR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FGFR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FGFR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FGFR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FGFR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 FGFR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FGFR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FGFR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 FGFR4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
IKZF1 FGFR4 11981041 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002004E0 FGFR4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001919B0 FGFR4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE FGFR4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009A9A2 FGFR4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 FGFR4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D FGFR4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075A608 FGFR4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A FGFR4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 FGFR4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D FGFR4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C FGFR4 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 FGFR4 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
STAT1 FGFR4 10918587 11294897 11839738 12637327 12817007 14525934 15322115 25348397 7543024 7657660 7690989 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
WIF1 FGFR4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTPN6 FGFR4 25348397 N/A physical interaction ComPPI
MMP14 FGFR4 20798051 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ERRFI1 FGFR4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTPN11 FGFR4 25348397 N/A physical interaction ComPPI
FGF3 FGFR4 14525934 25348397 8663044 N/A experimental interaction detection,in vitro ComPPI,HPRD
FGF5 FGFR4 14525934 24234451 25241761 25348397 8663044 physical association experimental interaction detection,physical interaction,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
FGF9 FGFR4 14525934 25348397 8663044 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN12 FGFR4 25348397 N/A physical interaction ComPPI
PKM FGFR4 25348397 N/A protein kinase assay ComPPI
PSMC3IP FGFR4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EPHA4 FGFR4 14525934 16365308 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CDK9 FGFR4 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
FCGRT FGFR4 25348397 N/A physical interaction ComPPI
STAT3 FGFR4 10918587 11294897 11350938 11940572 12244095 12576423 12626508 14525934 14551213 25348397 8626374 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CASC3 FGFR4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TNFRSF10A FGFR4 25348397 N/A physical interaction ComPPI
CDH2 FGFR4 14525934 25348397 9168198 N/A experimental interaction detection,in vitro ComPPI,HPRD
FGFR4 FGF7 14525934 25348397 7680645 N/A experimental interaction detection,in vivo ComPPI,HPRD
FGFR4 FGF4 14525934 25348397 8663044 N/A experimental interaction detection,in vitro ComPPI,HPRD
FGFR4 FGF17 10751172 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
FGFR4 FGF18 25348397 N/A in vitro ComPPI
FGFR4 FGF1 10336501 10736564 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,biochemical,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
FGFR4 FGF2 14525934 25348397 8530375 N/A experimental interaction detection,physical interaction,biochemical,in vitro ComPPI,HPRD
FGFR4 FGF6 1385111 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FGFR4 FGF8 10736564 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FGFR4 ANGPTL4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FGFR4 DIRAS3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FGFR4 EPSTI1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FGFR4 OSGIN1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FGFR4 RASL10B 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FGFR4 SCGB3A1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FGFR4 TMX1 25348397 N/A physical interaction ComPPI
FGFR4 MRAP2 25348397 N/A physical interaction ComPPI
FGFR4 PPP3CA 25348397 N/A physical interaction ComPPI
RNF20 FGFR4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FGFR4 PLCG1 14525934 7518429 N/A experimental interaction detection HPRD
FGFR4 STAT1 10918587 11294897 11839738 12637327 12817007 15322115 27898060 7543024 7657660 7690989 stimulant N/A OmniPath
FGFR4 CBL 10608804 10829062 12604776 15922744 27898060 N/A N/A OmniPath
FGFR4 STAT3 10918587 11294897 11350938 11940572 12244095 12576423 12626508 14551213 16497976 17016520 17389395 19901323 27898060 8626374 stimulant N/A OmniPath
FGF2 FGFR4 1385111 27898060 7680645 8530375 stimulant N/A OmniPath
FGF6 FGFR4 1385111 27898060 stimulant N/A OmniPath
FGF4 FGFR4 11486033 1385111 27898060 8663044 stimulant N/A OmniPath
FGF1 FGFR4 10336501 10736564 1385111 25241761 27898060 7680645 stimulant N/A OmniPath
FGF16 FGFR4 16597617 27898060 stimulant N/A OmniPath
FGF20 FGFR4 15621532 27898060 stimulant N/A OmniPath

Visualization










  Return