Gene Information gene info

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GENE：PRDX2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PRDX2
FullNmae peroxiredoxin 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9353
EnsembleID ENSG00000167815
Uniprot P32119

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PRDX2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PRDX2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PRDX2 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PRDX2 GO:0002357,GO:0002536,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0006979,GO:0006979,GO:0006979,GO:0008379,GO:0008379,GO:0008379,GO:0010310,GO:0016209,GO:0016209,GO:0019430,GO:0019430,GO:0030194,GO:0031665,GO:0032496,GO:0033554,GO:0034599,GO:0042098,GO:0042744,GO:0042744,GO:0042981,GO:0043029,GO:0043066,GO:0043410,GO:0045321,GO:0045454,GO:0045581,GO:0048538,GO:0070062,GO:0097191,GO:2001240

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL7R PRDX2 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR PRDX2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 PRDX2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 PRDX2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PRDX2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 PRDX2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PRDX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PRDX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PRDX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PRDX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PRDX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PRDX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PRDX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PRDX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 PRDX2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000003FD55 PRDX2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 PRDX2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000016914 PRDX2 25416803 26633009 mrna cleavage,inhibition western blot,electrophoretic mobility-based method,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
PRDX2 PRDX2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LDHA PRDX2 25348397 N/A physical interaction ComPPI
PCBP1 PRDX2 25348397 N/A physical interaction ComPPI
SAT1 PRDX2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP2R1A PRDX2 14525934 17540176 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
GABARAPL2 PRDX2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KEAP1 PRDX2 25348397 N/A physical interaction ComPPI
MCM2 PRDX2 25348397 N/A physical interaction ComPPI
MAP1LC3B PRDX2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CYCS PRDX2 25348397 N/A physical interaction ComPPI
BAD PRDX2 21988832 24234451 25348397 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
JUN PRDX2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 PRDX2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
U2AF2 PRDX2 25348397 N/A physical interaction ComPPI
DUT PRDX2 25348397 N/A physical interaction ComPPI
GAPDH PRDX2 25348397 N/A physical interaction ComPPI
YWHAZ PRDX2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PDGFRB PRDX2 14525934 15902258 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
DLD PRDX2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MSH6 PRDX2 25348397 N/A physical interaction ComPPI
PRDX4 PRDX2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX1 PRDX2 25348397 N/A physical interaction ComPPI
APOE PRDX2 25348397 N/A physical interaction ComPPI
TXN PRDX2 17557078 24234451 25348397 25402766 association,physical association cross-linking study,pull down,physical interaction ComPPI,IntAct
CACYBP PRDX2 25348397 N/A physical interaction ComPPI
CFTR PRDX2 25348397 N/A physical interaction ComPPI
FSCN1 PRDX2 25348397 N/A physical interaction ComPPI
EWSR1 PRDX2 25348397 N/A physical interaction ComPPI
PKM PRDX2 25348397 N/A physical interaction ComPPI
IPO11 PRDX2 25348397 N/A physical interaction ComPPI
CUL2 PRDX2 25348397 N/A physical interaction ComPPI
SPR PRDX2 25348397 N/A physical interaction ComPPI
TPI1 PRDX2 25348397 N/A physical interaction ComPPI
ANXA11 PRDX2 25348397 N/A physical interaction ComPPI
PPA1 PRDX2 25348397 N/A physical interaction ComPPI
CDK2 PRDX2 25348397 N/A physical interaction ComPPI
CUL1 PRDX2 25348397 N/A physical interaction ComPPI
ANXA2 PRDX2 25348397 N/A physical interaction ComPPI
FUBP1 PRDX2 25348397 N/A physical interaction ComPPI
GABARAP PRDX2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MAP1LC3A PRDX2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
STK4 PRDX2 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
VCAM1 PRDX2 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ITGA4 PRDX2 25348397 N/A physical interaction ComPPI
DNM1L PRDX2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PRDX6 PRDX2 25348397 N/A physical interaction ComPPI
NLGN3 PRDX2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CAND1 PRDX2 25348397 N/A physical interaction ComPPI
CA4 PRDX2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ASS1 PRDX2 25348397 N/A physical interaction ComPPI
FOXA1 PRDX2 25348397 N/A physical interaction ComPPI
CDC37 PRDX2 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MAST1 PRDX2 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NFKB1 PRDX2 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
BAX PRDX2 25348397 N/A physical interaction ComPPI
ANKRA2 PRDX2 25348397 N/A physical interaction ComPPI
PCMT1 PRDX2 25348397 N/A physical interaction ComPPI
TRIM25 PRDX2 25348397 N/A physical interaction ComPPI
MPP1 PRDX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RIF1 PRDX2 25348397 N/A physical interaction ComPPI
ECSIT PRDX2 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ESR1 PRDX2 25348397 N/A physical interaction ComPPI
PDCD6IP PRDX2 25348397 N/A physical interaction ComPPI
UBE2H PRDX2 25348397 N/A physical interaction ComPPI
PPP2R1B PRDX2 14525934 17540176 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
METTL1 PRDX2 25348397 N/A physical interaction ComPPI
STAT3 PRDX2 24234451 25348397 25402766 association,physical association pull down,physical interaction ComPPI,IntAct
PARK7 PRDX2 25348397 N/A physical interaction ComPPI
HECW2 PRDX2 25348397 N/A physical interaction ComPPI
TALDO1 PRDX2 25348397 N/A physical interaction ComPPI
SOD1 PRDX2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
KHSRP PRDX2 25348397 N/A physical interaction ComPPI
ATP6V1A PRDX2 25348397 N/A physical interaction ComPPI
PPP2R5D PRDX2 25348397 N/A physical interaction ComPPI
UBA3 PRDX2 25348397 N/A physical interaction ComPPI
NES PRDX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRDX3 PRDX2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
DAZAP1 PRDX2 25348397 N/A physical interaction ComPPI
CAT PRDX2 25348397 N/A physical interaction ComPPI
UCHL5 PRDX2 25348397 N/A physical interaction ComPPI
PSEN1 PRDX2 25348397 N/A physical interaction ComPPI
A2M PRDX2 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HSD17B10 PRDX2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
KCTD5 PRDX2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
CYLD PRDX2 25348397 N/A physical interaction ComPPI
PAICS PRDX2 25348397 N/A physical interaction ComPPI
GABARAPL1 PRDX2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
COL14A1 PRDX2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
RETREG2 PRDX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HINT1 PRDX2 25348397 N/A physical interaction ComPPI
PRDX2 SUMO4 14525934 16236267 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PRDX2 APP 25348397 N/A physical interaction ComPPI
PRDX2 EXOC6 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PRDX2 IFIT5 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PRDX2 RNF32 21163940 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PRDX2 URM1 25348397 N/A physical interaction ComPPI
PRDX2 PRDX5 25348397 N/A physical interaction ComPPI
PRDX2 SGSH 25348397 N/A physical interaction ComPPI
PRDX2 TIPRL 25348397 N/A physical interaction ComPPI
PRDX2 TMEM9 25348397 N/A physical interaction ComPPI
PRDX2 SEC23IP 25348397 N/A physical interaction ComPPI
PRDX2 FN1 25348397 N/A physical interaction ComPPI
PRDX2 RAD52 19338310 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRDX2 CD320 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX2 UTY 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRDX2 PPT1 25348397 N/A physical interaction ComPPI
PRDX2 ANXA2P2 25348397 N/A physical interaction ComPPI
PRDX2 NAXD 25348397 N/A physical interaction ComPPI
PRDX2 CDK1 25348397 N/A physical interaction ComPPI
PRDX2 GLOD4 25348397 N/A physical interaction ComPPI
PRDX2 GPX4 25348397 N/A physical interaction ComPPI
PRDX2 LAP3 25348397 N/A physical interaction ComPPI
PRDX2 NANS 25348397 N/A physical interaction ComPPI
PRDX2 PGAM1 25348397 N/A physical interaction ComPPI
PRDX2 UBE2T 25348397 N/A physical interaction ComPPI
PRDX2 RNASEH2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRDX2 ANAPC15 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRDX2 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRDX2 RTL9 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PRDX2 MAK 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PRDX2 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
METTL3 PRDX2 24234451 29507755 association anti tag coimmunoprecipitation IntAct
WTAP PRDX2 24234451 29507755 association anti tag coimmunoprecipitation IntAct
METTL14 PRDX2 24234451 29507755 association anti tag coimmunoprecipitation IntAct
IL7R PRDX2 20167604 27898060 N/A N/A OmniPath

Visualization










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