Gene Information gene info

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GENE：FOXL2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FOXL2
FullNmae forkhead box L2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1092
EnsembleID ENSG00000183770
Uniprot P58012

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FOXL2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FOXL2 GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0001541,GO:0001541,GO:0001555,GO:0002074,GO:0003677,GO:0003677,GO:0003700,GO:0003700,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006309,GO:0006357,GO:0007338,GO:0009653,GO:0019101,GO:0030154,GO:0030154,GO:0030331,GO:0031624,GO:0033686,GO:0043028,GO:0043065,GO:0043065,GO:0043280,GO:0045892,GO:0045893,GO:0045944,GO:0046881,GO:0048048,GO:0060014,GO:0060065,GO:0090543,GO:1990837

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 FOXL2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF FOXL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FOXL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FOXL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 FOXL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000032BD73 FOXL2 23810756 25416803 mrna cleavage,inhibition western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000458AD2 FOXL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000057FDB8 FOXL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000003E1A9 FOXL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 FOXL2 25416803 25621074 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
GSK3B FOXL2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
UBE2I FOXL2 25348397 N/A physical interaction ComPPI
HK2 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
GLYR1 FOXL2 25348397 N/A physical interaction ComPPI
FIP1L1 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
LARP1 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PAK1 FOXL2 25348397 N/A in vitro,in vivo ComPPI
TTF2 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
TTF1 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SMAD3 FOXL2 25348397 N/A physical interaction ComPPI
XRCC6 FOXL2 25348397 N/A physical interaction ComPPI
ANP32C FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SP100 FOXL2 25348397 N/A physical interaction ComPPI
RPLP1 FOXL2 25348397 N/A physical interaction ComPPI
BANF1 FOXL2 25348397 N/A physical interaction ComPPI
GMEB1 FOXL2 25348397 N/A physical interaction ComPPI
SIRT1 FOXL2 25348397 N/A physical interaction ComPPI
RBMX FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NR2C1 FOXL2 25348397 N/A physical interaction ComPPI
BTAF1 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
IARS1 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ELAVL1 FOXL2 25348397 N/A physical interaction ComPPI
SRPK2 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SIX1 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
LATS1 FOXL2 20407010 25348397 27898060 N/A physical interaction ComPPI,OmniPath
DDX39A FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PUF60 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
POP1 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 HNRNPUL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 SMPD4 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 YARS1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 NSDHL 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 PDS5A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 VARS1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 ACSL4 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 FUBP3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 NUP205 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 P4HA1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 SMC2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 UBE4A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 CMSS1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 MOV10 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 NKRF 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 LARP7 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 CCDC59 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 DDX52 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 TRMT2A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 DARS2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 DHX16 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 DNAJC9 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 GADD45GIP1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 MRPL21 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 MRPL24 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 MRPL3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 MRPS18A 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 NSUN4 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 PES1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 RECQL4 25348397 N/A physical interaction ComPPI
FOXL2 RTCA 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 SUGP2 25348397 N/A physical interaction ComPPI
FOXL2 THRAP3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 ZFR 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 CXXC5 25348397 N/A physical interaction ComPPI
FOXL2 CREM 25348397 N/A physical interaction ComPPI
POMGNT2 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
DCUN1D5 FOXL2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXL2 FOXL2 24234451 25609649 association tandem affinity purification IntAct
SIRT1 FOXL2 19010791 27898060 inhibition N/A OmniPath
UBE2I FOXL2 19744555 27898060 stimulant N/A OmniPath
PAK1 FOXL2 12560069 27898060 N/A N/A OmniPath
GSK3B FOXL2 22022399 24390485 25871347 27898060 N/A N/A OmniPath
DDX20 FOXL2 16153597 27898060 stimulant N/A OmniPath

Visualization










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