GENE：HRAS
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | HRAS |
| FullNmae | HRas proto-oncogene, GTPase |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:5173 |
| EnsembleID | ENSG00000174775 |
| Uniprot | P01112 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| HRAS | pyroptosis | 39879704 | Panax ginseng that maintains cytoskeletal homeostasis and inhibits pyroptosis by regulating the FGFR1/HRAS pathway to resist CIC. | retulator signature |
| HRAS | necroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| HRAS | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| HRAS | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| HRAS | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| HRAS | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| HRAS | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| HRAS | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| HRAS | GO:0000139,GO:0000165,GO:0001934,GO:0003924,GO:0003924,GO:0003924,GO:0003924,GO:0003925,GO:0005515,GO:0005525,GO:0005525,GO:0005525,GO:0005654,GO:0005737,GO:0005789,GO:0005794,GO:0005829,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0006357,GO:0006897,GO:0006935,GO:0007165,GO:0007166,GO:0007265,GO:0007265,GO:0008284,GO:0008285,GO:0008286,GO:0009887,GO:0010629,GO:0010863,GO:0019003,GO:0019003,GO:0030335,GO:0032729,GO:0032956,GO:0034260,GO:0042088,GO:0042127,GO:0042832,GO:0043406,GO:0043410,GO:0043495,GO:0043524,GO:0043547,GO:0045944,GO:0046330,GO:0048144,GO:0048146,GO:0048169,GO:0048471,GO:0050679,GO:0050852,GO:0051402,GO:0051726,GO:0060612,GO:0070374,GO:0071480,GO:0090303,GO:0090314,GO:0090398,GO:0090398,GO:0090402,GO:0097193,GO:0098696,GO:0098696,GO:0098978,GO:0098978,GO:1900029,GO:1905360,GO:2000630 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| HRAS | hsa:3265 | path:hsa01521 | EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa01522 | Endocrine resistance - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04010 | MAPK signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04012 | ErbB signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04014 | Ras signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04015 | Rap1 signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04062 | Chemokine signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04068 | FoxO signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04071 | Sphingolipid signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04072 | Phospholipase D signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04137 | Mitophagy - animal - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04140 | Autophagy - animal - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04144 | Endocytosis - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04150 | mTOR signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04151 | PI3K-Akt signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04210 | Apoptosis - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04211 | Longevity regulating pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04213 | Longevity regulating pathway - multiple species - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04218 | Cellular senescence - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04360 | Axon guidance - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04370 | VEGF signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04371 | Apelin signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04510 | Focal adhesion - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04540 | Gap junction - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04550 | Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04625 | C-type lectin receptor signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04630 | JAK-STAT signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04650 | Natural killer cell mediated cytotoxicity - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04660 | T cell receptor signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04662 | B cell receptor signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04664 | Fc epsilon RI signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04714 | Thermogenesis - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04720 | Long-term potentiation - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04722 | Neurotrophin signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04725 | Cholinergic synapse - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04726 | Serotonergic synapse - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04730 | Long-term depression - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04810 | Regulation of actin cytoskeleton - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04910 | Insulin signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04912 | GnRH signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04915 | Estrogen signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04916 | Melanogenesis - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04917 | Prolactin signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04919 | Thyroid hormone signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04921 | Oxytocin signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04926 | Relaxin signaling pathway - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04929 | GnRH secretion - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04933 | AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa04935 | Growth hormone synthesis, secretion and action - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05010 | Alzheimer disease - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05022 | Pathways of neurodegeneration - multiple diseases - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05034 | Alcoholism - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05132 | Salmonella infection - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05160 | Hepatitis C - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05161 | Hepatitis B - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05163 | Human cytomegalovirus infection - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05165 | Human papillomavirus infection - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05166 | Human T-cell leukemia virus 1 infection - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05167 | Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05170 | Human immunodeficiency virus 1 infection - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05200 | Pathways in cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05203 | Viral carcinogenesis - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05205 | Proteoglycans in cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05206 | MicroRNAs in cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05207 | Chemical carcinogenesis - receptor activation - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05208 | Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05210 | Colorectal cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05211 | Renal cell carcinoma - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05213 | Endometrial cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05214 | Glioma - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05215 | Prostate cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05216 | Thyroid cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05218 | Melanoma - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05219 | Bladder cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05220 | Chronic myeloid leukemia - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05221 | Acute myeloid leukemia - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05223 | Non-small cell lung cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05224 | Breast cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05225 | Hepatocellular carcinoma - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05226 | Gastric cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05230 | Central carbon metabolism in cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05231 | Choline metabolism in cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human) |
| HRAS | hsa:3265 | path:hsa05417 | Lipid and atherosclerosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HRAS | YWHAB | 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 26192618 7510700 8551221 9069260 9763606 9846483 | interaction type | N/A | ACSN |
| RAF1 | HRAS | 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 26192618 7510700 8551221 9069260 9763606 9846483 | interaction type | N/A | ACSN |
| RASGRP1 | HRAS | 10777492 10807788 10835426 10934204 11221888 12782630 14764585 15184873 17283063 17496910 24027568 26192618 29145629 | interaction type,enzymatic reaction | inferred by curator | ACSN,Reactome |
| VAV2 | HRAS | 10934226 11080163 11262396 12094222 14623913 15365099 15886116 16713974 26192618 9822605 | interaction type | N/A | ACSN |
| HRAS | TIAM1 | 10358164 12134164 12447393 14764585 16102570 17673906 20841469 24027568 24954210 26192618 7510700 7673236 8551221 9069260 9763606 9846483 | interaction type | N/A | ACSN |
| HRAS | CDKN2A | 10358164 12134164 12447393 14764585 16102570 17673906 20841469 24027568 24954210 26192618 7510700 7673236 8551221 9069260 9763606 9846483 | interaction type | N/A | ACSN |
| HRAS | TRAF6 | 11744690 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| HRAS | MAP3K7 | 11744690 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| HRAS | IRAK2 | 11744690 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| HRAS | TTC1 | 12748287 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| HRAS | GPSM2 | 12748287 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| HRAS | RASIP1 | 15031288 23180781 | physical association | anti tag coimmunoprecipitation,two hybrid,gst pull down | InnateDB |
| HRAS | RAP1GDS1 | 11948427 23180781 | physical association | anti tag coimmunoprecipitation,two hybrid,gst pull down | InnateDB |
| HRAS | IKZF3 | 10369681 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| HRAS | DGKZ | 11257115 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| HRAS | ERBIN | 12379659 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| HRAS | PDE6D | 11980706 23180781 | physical association | two hybrid | InnateDB |
| HRAS | AFDN | 10545207 10922060 23180781 | physical association | two hybrid | InnateDB |
| HRAS | PIK3CG | 10922060 23180781 | physical association | two hybrid | InnateDB |
| HRAS | IRAK1 | 11744690 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| HRAS | RASSF2 | 12732644 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| TIAM1 | HRAS | 12134164 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| HRAS | PIK3CA | 23180781 9113989 9150145 | physical association | gst pull down | InnateDB |
| HRAS | RALGDS | 10545207 10783161 10922060 23180781 9150145 | physical association | two hybrid,gst pull down | InnateDB |
| HRAS | RHOD | 15187129 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| HRAS | PLCE1 | 11022048 23180781 | physical association | affinity chromatography technology,anti tag coimmunoprecipitation | InnateDB |
| ITSN1 | HRAS | 12970366 23180781 | physical association | anti tag coimmunoprecipitation,fluorescent resonance energy transfer | InnateDB |
| HRAS | SHOC2 | 10783161 16301319 23180781 | physical association | anti tag coimmunoprecipitation,two hybrid | InnateDB |
| SHOC2 | HRAS | 10783161 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| HRAS | PIK3CD | 10545207 23180781 9113989 | physical association | two hybrid,gst pull down | InnateDB |
| HRAS | VAV1 | 1377053 1569084 23180781 29145629 8554611 | phosphorylation reaction,enzymatic reaction | inferred by curator,protein kinase assay | InnateDB,Reactome |
| HRAS | ARAF | 10545207 23180781 | physical association | two hybrid | InnateDB |
| HRAS | BRAF | 10545207 16803888 18098337 18988627 23180781 23331499 7706312 9154803 | stimulation,physical association | anti tag coimmunoprecipitation,two hybrid | InnateDB,SignaLink,SignaLink |
| HRAS | RLF | 10545207 23180781 | physical association | two hybrid,gst pull down | InnateDB |
| HRAS | RIN1 | 10545207 11784866 23180781 | physical association | two hybrid,gst pull down,surface plasmon resonance | InnateDB |
| HRAS | RAF1 | 10545207 10783161 10882715 10922060 11733498 12379659 12391160 12620389 14654780 14724584 15031288 15688026 16041367 16301319 18988627 21071413 23180781 23331499 7730360 8035810 8332187 8332195 8530446 8911690 9020159 9099670 9150145 9154803 9261098 | stimulation,physical association | anti tag coimmunoprecipitation,two hybrid,gst pull down | InnateDB,SignaLink,SignaLink |
| HRAS | TLR2 | 15007072 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| HRAS | NF1 | 23180781 8628317 | physical association | two hybrid | InnateDB |
| HRAS | RGL2 | 23180781 8939933 | physical association | two hybrid | InnateDB |
| RGS14 | HRAS | 23180781 23250758 | physical association | bioluminescence resonance energy transfer | InnateDB |
| HRAS | MAPK3 | 10209122 10409742 10725339 10891492 12473660 12832465 14636584 14970219 15035987 15543157 16135787 16879721 17496912 17563371 19091303 19219045 19242111 19279408 21779496 22177953 22510884 22569528 23352452 24957944 25907612 29145629 3287375 7565670 7565795 7731720 7929275 7935411 8051079 8157000 9020159 9858547 | physical association | inferred by curator | Reactome |
| HRAS | MAPK1 | 10209122 10409742 10725339 10891492 12473660 12832465 14636584 14970219 15035987 15543157 16135787 16879721 17496912 17563371 19091303 19219045 19242111 19279408 21779496 22177953 22510884 22569528 23352452 24957944 25907612 29145629 3287375 7565670 7565795 7731720 7929275 7935411 8051079 8157000 9020159 9858547 | physical association | inferred by curator | Reactome |
| HRAS | SOS1 | 10722704 11157491 11429702 12147692 1371879 1377053 15118125 15284455 1569084 16024644 16129412 16483568 1721591 18381441 18757403 19103595 19946327 20179196 21160078 21666749 21711248 24243840 24588013 25467007 29145629 7731718 7970720 8388543 8493579 8530489 8530511 8622888 9038378 9070211 9690470 9739761 9857065 | enzymatic reaction | inferred by curator | Reactome |
| HRAS | IRS1 | 24243840 29145629 | enzymatic reaction | inferred by curator | Reactome |
| HRAS | IRS2 | 24243840 29145629 | enzymatic reaction | inferred by curator | Reactome |
| HRAS | RASGRP3 | 10777492 10835426 10934204 11221888 17283063 29145629 | enzymatic reaction | inferred by curator | Reactome |
| HRAS | HRAS | 18098337 21779497 26467481 8052307 9020159 | bind,up-regulates,up-regulates activity | N/A | Signor |
| SOS1 | HRAS | 10913276 23331499 9690470 | stimulation | N/A | SignaLink |
| RASA1 | HRAS | 23331499 9219684 | stimulation | N/A | SignaLink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | HRAS | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | HRAS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | HRAS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | HRAS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | HRAS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | HRAS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | HRAS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | HRAS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | HRAS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| BTG2 | HRAS | 20197462 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MAZ | HRAS | 21931711 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SP1 | HRAS | 21931711 3012774 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| DAND5 | HRAS | 21931711 3012774 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | HRAS | 11127813 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NFIC | HRAS | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TFAP2A | HRAS | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000008A99 | HRAS | 21276449 | rna interference,inhibition | northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
| URS0000236310 | HRAS | 22207524 | rna interference,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | miRSponge |
| URS0000008A99 | HRAS | 21276449 25416803 25477374 | mrna cleavage,inhibition | experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS0000324096 | HRAS | 21252116 25416803 | mrna cleavage,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr | TarBase |
| URS0000236310 | HRAS | 22207524 25416803 | mrna cleavage,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | TarBase |
| URS00003D5391 | HRAS | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000023BE29 | HRAS | 24158791 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS00004929F1 | HRAS | 23953123 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS00005A8A8D | HRAS | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000033B91D | HRAS | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002373FD | HRAS | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000076E54 | HRAS | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000054D341 | HRAS | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B0B46 | HRAS | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SRC | HRAS | 22135298 25361965 | interaction type,phosphorylation | N/A | PhosphoSite,PTMCode2 |
| ABL1 | HRAS | 22135298 | phosphorylation | N/A | PhosphoSite |
| GSK3B | HRAS | 22135298 | phosphorylation | N/A | PhosphoSite |
| ABL2 | HRAS | 22135298 | phosphorylation | N/A | PhosphoSite |
| HRAS | RASGRP1 | 25361965 | interaction type | N/A | PTMCode2 |
| RASGRP1 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | RIN1 | 25361965 | interaction type | N/A | PTMCode2 |
| RIN1 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | ZHX2 | 25361965 | interaction type | N/A | PTMCode2 |
| ZHX2 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | BCL2 | 25361965 | interaction type | N/A | PTMCode2 |
| BCL2 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | PDGFB | 25361965 | interaction type | N/A | PTMCode2 |
| PDGFB | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | GRB2 | 25361965 | interaction type | N/A | PTMCode2 |
| GRB2 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | RAP1GDS1 | 25361965 | interaction type | N/A | PTMCode2 |
| RAP1GDS1 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | ICMT | 25361965 | interaction type | N/A | PTMCode2 |
| ICMT | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | RASSF1 | 25361965 | interaction type | N/A | PTMCode2 |
| RASSF1 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | SRC | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | PIK3CG | 25361965 | interaction type | N/A | PTMCode2 |
| PIK3CG | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | MAPK10 | 25361965 | interaction type | N/A | PTMCode2 |
| MAPK10 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | FYN | 25361965 | interaction type | N/A | PTMCode2 |
| FYN | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | SHOC2 | 25361965 | interaction type | N/A | PTMCode2 |
| SHOC2 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | ARAF | 25361965 | interaction type | N/A | PTMCode2 |
| ARAF | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | PIK3CD | 25361965 | interaction type | N/A | PTMCode2 |
| PIK3CD | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | TP73 | 25361965 | interaction type | N/A | PTMCode2 |
| TP73 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | PRKCZ | 25361965 | interaction type | N/A | PTMCode2 |
| PRKCZ | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | RASSF2 | 25361965 | interaction type | N/A | PTMCode2 |
| RASSF2 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | SOS1 | 25361965 | interaction type | N/A | PTMCode2 |
| SOS1 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | RASGRF1 | 25361965 | interaction type | N/A | PTMCode2 |
| RASGRF1 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | RGL2 | 25361965 | interaction type | N/A | PTMCode2 |
| RGL2 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | IKZF3 | 25361965 | interaction type | N/A | PTMCode2 |
| IKZF3 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| RASGRP2 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | RASGRP2 | 25361965 | interaction type | N/A | PTMCode2 |
| PIK3CA | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | PIK3CA | 25361965 | interaction type | N/A | PTMCode2 |
| RAF1 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | RAF1 | 25361965 | interaction type | N/A | PTMCode2 |
| TIAM1 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | TIAM1 | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | FNTA | 25361965 | interaction type | N/A | PTMCode2 |
| FNTA | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | SMAD4 | 25361965 | interaction type | N/A | PTMCode2 |
| SMAD4 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| BRAF | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | BRAF | 25361965 | interaction type | N/A | PTMCode2 |
| SOS2 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | SOS2 | 25361965 | interaction type | N/A | PTMCode2 |
| MAP2K1 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | MAP2K1 | 25361965 | interaction type | N/A | PTMCode2 |
| RGL4 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | RGL4 | 25361965 | interaction type | N/A | PTMCode2 |
| PLCE1 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | PLCE1 | 25361965 | interaction type | N/A | PTMCode2 |
| PIK3R1 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | PIK3R1 | 25361965 | interaction type | N/A | PTMCode2 |
| HGF | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | HGF | 25361965 | interaction type | N/A | PTMCode2 |
| RALA | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | RALA | 25361965 | interaction type | N/A | PTMCode2 |
| INSR | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | INSR | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| GRB14 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| HRAS | GRB14 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| KRT18 | HRAS | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| HOXB5 | HRAS | 25348397 | N/A | physical interaction | ComPPI |
| PPP1R13B | HRAS | 25348397 | N/A | physical interaction | ComPPI |
| SPRY2 | HRAS | 25348397 | N/A | physical interaction | ComPPI |
| SH3KBP1 | HRAS | 25348397 | N/A | physical interaction | ComPPI |
| PDE6D | HRAS | 11980706 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
| AGTR1 | HRAS | 25348397 | N/A | in vitro,in vivo | ComPPI |
| RABGGTB | HRAS | 25348397 | N/A | physical interaction | ComPPI |
| SMAD4 | HRAS | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| RASSF5 | HRAS | 14525934 18596699 24234451 25348397 9488663 | physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,nuclear magnetic resonance,physical interaction,in vitro | ComPPI,HPRD,IntAct |
| MED21 | HRAS | 25348397 | N/A | physical interaction | ComPPI |
| PSMB2 | HRAS | 25348397 | N/A | physical interaction | ComPPI |
| RIN1 | HRAS | 14525934 15886098 24234451 25348397 7862125 9144171 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,nuclear magnetic resonance,physical interaction,biochemical,genetic,in vitro,two hybrid | ComPPI,HPRD,IntAct |
| RABAC1 | HRAS | 11335720 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vivo,two hybrid | ComPPI,HPRD |
| DUSP12 | HRAS | 25348397 | N/A | physical interaction | ComPPI |
| RNF115 | HRAS | 25348397 | N/A | physical interaction | ComPPI |
| ERBIN | HRAS | 25348397 | N/A | physical interaction | ComPPI |
| CBL | HRAS | 25348397 | N/A | physical interaction | ComPPI |
| VAV1 | HRAS | 14525934 25348397 8554611 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| HRAS | PIK3R1 | 10212255 14525934 24234451 25241761 25348397 | physical association | experimental interaction detection,physical interaction,in vivo,proximity ligation assay | ComPPI,HPRD,IntAct |
| HRAS | PIK3CA | 14525934 24234451 24412244 25348397 9150145 | physical association | two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo | ComPPI,HPRD,IntAct |
| HRAS | MAP2K1 | 14525934 25348397 7969158 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| HRAS | SOS1 | 11560935 12628188 14525934 15507210 17084389 18454158 19141281 20133692 24234451 25348397 9447984 9690470 | physical association | experimental interaction detection,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,enzymatic study,in vivo,gdp/gtp exchange assay | ComPPI,HPRD,IntAct |
| HRAS | GRB2 | 11352655 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| HRAS | PDGFB | 10485711 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| HRAS | SRC | 12695509 14525934 24234451 25348397 | N/A | experimental interaction detection,pull down,in vitro | ComPPI,HPRD,IntAct |
| HRAS | IRAK1 | 11744690 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| HRAS | ARAF | 12620389 14525934 24234451 24441586 25348397 | physical association | two hybrid,isothermal titration calorimetry,nuclear magnetic resonance,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| HRAS | RAPGEF1 | 10514505 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| HRAS | TIAM1 | 12134164 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| HRAS | CAV1 | 14525934 24234451 25348397 8621645 | physical association | experimental interaction detection,pull down,imaging technique,in vitro | ComPPI,HPRD,IntAct |
| HRAS | MAPK8 | 11525649 14525934 16810318 25348397 8137421 | N/A | biophysical,experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| HRAS | PIK3CG | 11136978 14525934 24234451 25348397 | N/A | experimental interaction detection,x-ray crystallography,physical interaction,in vitro | ComPPI,HPRD,IntAct |
| HRAS | SOS2 | 12628188 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| HRAS | DGKZ | 11257115 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| HRAS | GRIN2D | 10862698 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| HRAS | SHOC2 | 10783161 14525934 16301319 24234451 25348397 9674433 | association | two hybrid,experimental interaction detection,pull down,physical interaction,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| HRAS | IRAK2 | 11744690 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| HRAS | RASGRP1 | 14525934 25348397 9582122 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| HRAS | RASSF1 | 10998413 14525934 18596699 24234451 25348397 | N/A | experimental interaction detection,fluorescence technology,pull down,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| HRAS | IKZF3 | 10369681 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| HRAS | GPSM2 | 12748287 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| HRAS | ICMT | 12750467 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| HRAS | RASGRP4 | 11880369 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| HRAS | RAP1GDS1 | 11948427 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| HRAS | RGL1 | 10545207 14525934 20936779 24234451 24441586 25348397 | physical association | two hybrid,isothermal titration calorimetry,nuclear magnetic resonance,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| HRAS | RASSF2 | 12732644 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| HRAS | RIT2 | 10545207 14525934 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| HRAS | ZBTB12 | 14525934 25348397 8939933 | N/A | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD |
| HRAS | GRIN1 | 10862698 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| HRAS | PLCE1 | 11022048 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD |
| HRAS | CDC25A | 14525934 25348397 7744247 | N/A | experimental interaction detection,physical interaction,biochemical,in vitro | ComPPI,HPRD |
| HRAS | ITSN1 | 12970366 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| HRAS | PRKCZ | 14525934 15721486 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| HRAS | IL3 | 10677502 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| HRAS | TLR2 | 14525934 15496409 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| HRAS | TLR9 | 12867418 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| HRAS | RHOD | 14525934 15187129 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| HRAS | FYN | 12695509 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| HRAS | TP73 | 14525934 16436381 25348397 27898060 | N/A | two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| HRAS | PLAAT4 | 14525934 16005186 25348397 27898060 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
| HRAS | RGS12 | 14525934 17380122 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| HRAS | RAP1B | 14525934 25348397 8332187 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| HRAS | CDC25C | 14525934 25348397 9154803 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| HRAS | RGL2 | 14525934 20936779 24234451 25348397 8939933 | physical association | experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro | ComPPI,HPRD,IntAct |
| HRAS | FNTA | 14525934 2217184 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| HRAS | FNTB | 14525934 15451670 2217184 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| HRAS | RASA1 | 14525934 24234451 25348397 2833817 7628625 8663024 9219684 | N/A | experimental interaction detection,x-ray crystallography,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| HRAS | INSR | 14525934 25348397 3109943 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| HRAS | LGALS1 | 11709720 14525934 22696230 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| HRAS | BCL2 | 10490827 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| HRAS | NF1 | 25348397 | N/A | physical interaction,in vitro | ComPPI |
| HRAS | BRAF | 14525934 16803888 24234451 24441586 25348397 26165597 7706312 9154803 | N/A | two hybrid,experimental interaction detection,molecular sieving,nuclear magnetic resonance,static light scattering,physical interaction,in vitro | ComPPI,HPRD,IntAct |
| HRAS | RAF1 | 12620389 14525934 15688026 16301319 18073111 18273062 19063885 19222999 19696784 20080631 20133694 20178605 22169110 24234451 24929361 25348397 25684575 7730360 8035810 8332187 8332195 8530446 8670882 8911690 9099670 9144171 9154803 9261098 | colocalization,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,fluorescent resonance energy transfer,molecular sieving,pull down,x-ray crystallography,physical interaction,in vitro,in vivo,confocal microscopy,two hybrid | ComPPI,HPRD,IntAct |
| HRAS | RASGRF1 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | RALGDS | 14525934 20936779 24234451 24441586 25241761 25348397 7972015 9038168 | physical association | experimental interaction detection,nuclear magnetic resonance,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,proximity ligation assay,two hybrid | ComPPI,HPRD,IntAct |
| HRAS | RASIP1 | 14525934 15031288 25348397 | N/A | experimental interaction detection,physical interaction,two hybrid | ComPPI,HPRD |
| HRAS | ARHGEF1 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | AFDN | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | PIK3CD | 22020336 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HRAS | RHEB | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | SNRPE | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | ZHX2 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | DEAF1 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | BTRC | 19240121 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| HRAS | KCTD7 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | RABGEF1 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | BRAP | 14724641 24234451 25348397 | physical association | coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
| HRAS | LATS2 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | TP53 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | TPR | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | SLC9A3R2 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | NEDD8 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | DAB2IP | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | ABL2 | 15886098 24234451 25348397 | association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HRAS | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | SNX17 | 21512128 24234451 25348397 27898060 | N/A | pull down,physical interaction | ComPPI,IntAct,OmniPath |
| HRAS | PHF19 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | SLC25A41 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | CD27 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | TMEM185A | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | PRXL2B | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | CYP51A1 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | DHCR24 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | BLID | 24234451 25348397 25640309 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| HRAS | CXCL1 | 24234451 25348397 25640309 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| HRAS | GREB1 | 24234451 25348397 25640309 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| HRAS | IL24 | 24234451 25348397 25640309 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| HRAS | PRSS50 | 24234451 25348397 25640309 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| HRAS | NIBAN2 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | DUSP22 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | DUSP9 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | CYP2S1 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | ATG3 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | VDAC3 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | PLCXD2 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | TIGD5 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | SGK1 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | MTHFD2 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | PCDHGC3 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | C1QL4 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | S1PR1 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | DUS4L | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | DEFB104A | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | GJB7 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | HDHD2 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | PMS1 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | NTRK3 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | SDC1 | 25348397 | N/A | physical interaction | ComPPI |
| HRAS | CDC25B | 25348397 | N/A | experimental interaction detection,physical interaction,biochemical | ComPPI |
| HRAS | FHOD1 | 18786395 24234451 25348397 27898060 | N/A | isothermal titration calorimetry,physical interaction | ComPPI,IntAct,OmniPath |
| HRAS | RGS14 | 24234451 24441586 25348397 | N/A | nuclear magnetic resonance,physical interaction | ComPPI,IntAct |
| HRAS | RALA | 19222999 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| HRAS | RAPGEF2 | 10608844 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| HRAS | BMPR1A | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| HRAS | BUB1 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| HRAS | CDH1 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| HRAS | CDKN2A | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| HRAS | CTNNA1 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| HRAS | FBXW7 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| HRAS | MLH3 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| HRAS | MSH2 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| HRAS | MSH6 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| HRAS | MUTYH | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| HRAS | PDGFRL | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| HRAS | PTPRJ | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| HRAS | STK11 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
| HRAS | JUN | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| TTC1 | HRAS | 12748287 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| PRKCI | HRAS | 10848576 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| PLAAT3 | HRAS | 25348397 | N/A | physical interaction | ComPPI |
| MGST3 | HRAS | 25348397 | N/A | physical interaction | ComPPI |
| RGL4 | HRAS | 12874025 14525934 9154803 | N/A | experimental interaction detection | HPRD |
| SRC | HRAS | 12695509 25157176 27898060 9626657 | inhibition,stimulant | N/A | OmniPath |
| GNAQ | HRAS | 27898060 9235901 | stimulant | N/A | OmniPath |
| MAP3K7 | HRAS | 11744690 27898060 | N/A | N/A | OmniPath |
| HRAS | BRAF | 10545207 16803888 18098337 21779497 24441586 27898060 7706312 8668348 9154803 | stimulant | N/A | OmniPath |
| TRAF6 | HRAS | 11744690 27898060 | N/A | N/A | OmniPath |
| HRAS | TLR2 | 15007072 15496409 27898060 | N/A | N/A | OmniPath |
| SOS1 | HRAS | 11560935 12628188 15507210 17084389 18454158 19141281 20133692 23132018 27898060 9447984 9690470 | stimulant | N/A | OmniPath |
| HRAS | PIK3CA | 10783161 14724584 24412244 27898060 8052307 8665852 9113989 9150145 | stimulant | N/A | OmniPath |
| TP53 | HRAS | 18431400 27898060 | stimulant | N/A | OmniPath |
| ABL1 | HRAS | 25999467 27898060 | N/A | N/A | OmniPath |
| HRAS | SHC1 | 17138645 27898060 | stimulant | N/A | OmniPath |
| HRAS | RIN1 | 10545207 11784866 15031288 15886098 24441586 27898060 7862125 9144171 | stimulant | N/A | OmniPath |
| RIN1 | HRAS | 10545207 11784866 15031288 15886098 24441586 27898060 7862125 9144171 | inhibition,stimulant | N/A | OmniPath |
| HRAS | PLCE1 | 11022048 11179219 27898060 | stimulant | N/A | OmniPath |
| PLCE1 | HRAS | 11022047 11022048 27898060 | inhibition,stimulant | N/A | OmniPath |
| HRAS | RAF1 | 10369681 10545207 10783161 10882715 10922060 11435472 11733498 12173045 12379659 12391160 12620389 14654780 14724584 15031288 15235600 15664191 15688026 16041367 16301319 16405865 16803888 17984326 18073111 18273062 19063885 19222999 19696784 20080631 20133694 20178605 21779497 24470255 25684575 27898060 7523381 7730360 7862125 7969158 8035810 8332187 8332195 8530446 8628317 8670882 8911690 9020159 9099670 9144171 9150145 9154803 9261098 9523700 | stimulant | N/A | OmniPath |
| PTPN11 | HRAS | 26617336 27898060 | stimulant | N/A | OmniPath |
| HRAS | RALGDS | 10545207 10783161 10922060 11786539 15031288 20936779 24441586 25241761 27898060 7809086 7972015 9038168 9150145 9154803 | stimulant | N/A | OmniPath |
| HRAS | NF1 | 27898060 8628317 | N/A | N/A | OmniPath |
| NF1 | HRAS | 19718661 27898060 8628317 | inhibition,stimulant | N/A | OmniPath |
| GSK3B | HRAS | 22494971 27898060 9264402 | N/A | N/A | OmniPath |
| HRAS | TIAM1 | 12134164 18568040 27898060 | stimulant | N/A | OmniPath |
| HRAS | ARAF | 10545207 12620389 21779497 24441586 27898060 | stimulant | N/A | OmniPath |
| HRAS | IRAK1 | 11744690 27898060 | N/A | N/A | OmniPath |
| ZDHHC9 | HRAS | 21779492 27898060 | stimulant | N/A | OmniPath |
| HRAS | JUN | 1749429 27898060 | stimulant | N/A | OmniPath |
| HRAS | ITSN1 | 12970366 27898060 | N/A | N/A | OmniPath |
| HRAS | IKZF3 | 10369681 27898060 | N/A | N/A | OmniPath |
| HRAS | TTC1 | 12748287 27898060 | N/A | N/A | OmniPath |
| TTC1 | HRAS | 12748287 27898060 | N/A | N/A | OmniPath |
| DAB2IP | HRAS | 27858941 27898060 | inhibition | N/A | OmniPath |
| HRAS | RASIP1 | 15031288 27898060 | N/A | N/A | OmniPath |
| RASIP1 | HRAS | 15031288 27898060 | N/A | N/A | OmniPath |
| HRAS | RHOD | 15187129 27898060 | N/A | N/A | OmniPath |
| HRAS | AFDN | 10334923 10545207 10922060 27898060 | stimulant | N/A | OmniPath |
| HRAS | RASSF2 | 12732644 27898060 | N/A | N/A | OmniPath |
| HRAS | PIK3CD | 10545207 11739523 21779497 22020336 27898060 9113989 9235916 | stimulant | N/A | OmniPath |
| RGS14 | HRAS | 23250758 24441586 27898060 | N/A | N/A | OmniPath |
| HRAS | RGS14 | 23250758 24441586 27898060 | N/A | N/A | OmniPath |
| HRAS | PIK3CB | 21779497 27898060 | stimulant | N/A | OmniPath |
| RASA1 | HRAS | 10394594 11389730 27898060 2833817 7628625 8663024 9219684 | inhibition,stimulant | N/A | OmniPath |
| HRAS | VAV1 | 27898060 8554611 | N/A | N/A | OmniPath |
| RGL2 | HRAS | 15031288 20936779 27898060 8939933 | N/A | N/A | OmniPath |
| HRAS | DGKZ | 11257115 27898060 | N/A | N/A | OmniPath |
| DGKZ | HRAS | 11257115 27898060 | N/A | N/A | OmniPath |
| SOS2 | HRAS | 12628188 21779497 27898060 | stimulant | N/A | OmniPath |
| HRAS | SHOC2 | 10783161 16301319 27898060 9674433 | N/A | N/A | OmniPath |
| PDE6D | HRAS | 11786539 11980706 27898060 | N/A | N/A | OmniPath |
| HRAS | IRAK2 | 11744690 27898060 | N/A | N/A | OmniPath |
| HRAS | ERBIN | 12379659 27898060 | N/A | N/A | OmniPath |
| ERBIN | HRAS | 12379659 27898060 | N/A | N/A | OmniPath |
| HRAS | PIK3CG | 10922060 11136978 21779497 27898060 9727023 | stimulant | N/A | OmniPath |
| HRAS | GPSM2 | 12748287 27898060 | N/A | N/A | OmniPath |
| GPSM2 | HRAS | 12748287 27898060 | N/A | N/A | OmniPath |
| HRAS | RLF | 10545207 27898060 | N/A | N/A | OmniPath |
| RAPGEF6 | HRAS | 19201597 27898060 | stimulant | N/A | OmniPath |
| RASGEF1C | HRAS | 19201597 27898060 | stimulant | N/A | OmniPath |
| FNTB | HRAS | 15451670 2217184 24294527 27898060 | stimulant | N/A | OmniPath |
| RAPGEF5 | HRAS | 19201597 27898060 | stimulant | N/A | OmniPath |
| FNTA | HRAS | 2217184 24294527 27898060 | stimulant | N/A | OmniPath |
| RASGEF1A | HRAS | 19201597 27898060 | stimulant | N/A | OmniPath |
| RASGEF1B | HRAS | 19201597 27898060 | stimulant | N/A | OmniPath |
| ICMT | HRAS | 12750467 27898060 | N/A | N/A | OmniPath |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009C4533 | HRAS | 27087310 | direct interaction,inhibition | N/A | NPInter |