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GENE：MCM10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MCM10
FullNmae minichromosome maintenance 10 replication initiation factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18043
EnsembleID ENSG00000065328
Uniprot Q7L590

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MCM10 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MCM10 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MCM10 GO:0003688,GO:0003697,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005730,GO:0006270,GO:0006270,GO:0006974,GO:0008283,GO:0019899,GO:0042802,GO:0043596,GO:0046872

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IKBKG MCM10 20098747 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 MCM10 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 MCM10 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MCM10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MCM10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MCM10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MCM10 15195143 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MCM10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MCM10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MCM10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MCM10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYCN MCM10 17826980 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 MCM10 19074876 rna interference,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00000B59A2 MCM10 19074876 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000AA464 MCM10 20304954 23622248 25416803 mrna cleavage,inhibition array technology,clash TarBase
URS0000521626 MCM10 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 MCM10 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00001C3AC1 MCM10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 MCM10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EED18 MCM10 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002367FA MCM10 24014023 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000075A608 MCM10 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 MCM10 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D MCM10 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 MCM10 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD MCM10 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 MCM10 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TRIM37 MCM10 25361965 interaction type N/A PTMCode2
MCM10 TRIM37 25361965 interaction type N/A PTMCode2
HAUS1 MCM10 25361965 interaction type N/A PTMCode2
MCM10 HAUS1 25361965 interaction type N/A PTMCode2
CDKN2C MCM10 25361965 interaction type N/A PTMCode2
MCM10 CDKN2C 25361965 interaction type N/A PTMCode2
MCM2 MCM10 25361965 interaction type N/A PTMCode2
MCM10 MCM2 25361965 interaction type N/A PTMCode2
CDC6 MCM10 25361965 interaction type N/A PTMCode2
MCM10 CDC6 25361965 interaction type N/A PTMCode2
CCND1 MCM10 25361965 interaction type N/A PTMCode2
MCM10 CCND1 25361965 interaction type N/A PTMCode2
CDKN1A MCM10 25361965 interaction type N/A PTMCode2
MCM10 CDKN1A 25361965 interaction type N/A PTMCode2
CDK6 MCM10 25361965 interaction type N/A PTMCode2
MCM10 CDK6 25361965 interaction type N/A PTMCode2
MCM7 MCM10 25361965 interaction type N/A PTMCode2
MCM10 MCM7 25361965 interaction type N/A PTMCode2
CCND2 MCM10 25361965 interaction type N/A PTMCode2
MCM10 CCND2 25361965 interaction type N/A PTMCode2
MCM10 CDC5L 25361965 interaction type N/A PTMCode2
CDC5L MCM10 25361965 interaction type N/A PTMCode2
MCM10 CCND3 25361965 interaction type N/A PTMCode2
CCND3 MCM10 25361965 interaction type N/A PTMCode2
MCM6 MCM10 25361965 interaction type N/A PTMCode2
MCM10 MCM6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GOLGA2 MCM10 25348397 N/A physical interaction ComPPI
CDC5L MCM10 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
ZBTB8A MCM10 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ZBTB43 MCM10 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RELL2 MCM10 25348397 N/A physical interaction ComPPI
CDKN1A MCM10 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
CCND1 MCM10 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
CDK6 MCM10 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
H2BC4 MCM10 25348397 N/A physical interaction ComPPI
MCM6 MCM10 11095689 14525934 15232106 16189514 24234451 25348397 physical association two hybrid,experimental interaction detection,protein array,physical interaction,two hybrid pooling approach,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
MCM2 MCM10 11095689 14525934 15232106 19917723 22433841 24234451 25348397 27898060 9154825 N/A two hybrid,experimental interaction detection,protein array,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
TNIP1 MCM10 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CCDC85B MCM10 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TEX264 MCM10 25348397 N/A physical interaction ComPPI
RBX1 MCM10 25348397 N/A physical interaction ComPPI
ORC4 MCM10 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
MCM10 CDKN2A 15232106 24234451 25348397 N/A protein array,physical interaction,in vitro ComPPI,IntAct
MCM10 ORC2 11095689 14525934 15232106 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,protein array,physical interaction,in vivo,confocal microscopy,two hybrid ComPPI,HPRD,IntAct
MCM10 CDC6 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
MCM10 ORC3 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
MCM10 CDC45 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
MCM10 CDC7 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
MCM10 HAUS1 14525934 15232106 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MCM10 MCM3 15232106 24234451 25348397 N/A two hybrid,protein array,physical interaction,in vitro,in vivo ComPPI,IntAct
MCM10 KRT15 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MCM10 TRIM37 14525934 16189514 19447967 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MCM10 CALCOCO2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MCM10 CEP72 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MCM10 HOOK2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MCM10 ZBTB8B 25348397 N/A two hybrid ComPPI
MCM10 NINL 14525934 16189514 24234451 25348397 26638075 association,physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,proximity-dependent biotin identification,two hybrid ComPPI,HPRD,IntAct
MCM10 DPPA2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MCM10 CEP70 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MCM10 CCND3 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
MCM10 MCM7 10783164 11095689 14525934 15232106 19064704 24234451 25348397 26186194 27898060 9154825 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
MCM10 RPAP1 25348397 N/A physical interaction ComPPI
MCM10 IKBKG 20098747 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
MCM10 DDB1 25348397 N/A physical interaction ComPPI
MCM10 CUL4A 25348397 N/A physical interaction ComPPI
MCM10 DCAF1 25348397 N/A physical interaction ComPPI
MCM10 APP 25348397 N/A physical interaction ComPPI
MCM10 CDKN2A 25348397 N/A physical interaction ComPPI
MCM10 TMEM171 25348397 N/A physical interaction ComPPI
MCM10 MCMBP 25348397 N/A physical interaction ComPPI
MCM10 MCM4 25348397 N/A physical interaction ComPPI
MCM10 SIRT1 25348397 N/A physical interaction ComPPI
MCM10 NTRK1 25348397 N/A physical interaction ComPPI
MCM10 H2BC11 25348397 N/A physical interaction ComPPI
MCM10 PCM1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MCM10 POLR2G 25348397 N/A physical interaction ComPPI
MCM10 SUPT5H 25348397 N/A physical interaction ComPPI
MCM10 OFD1 25348397 N/A physical interaction ComPPI
MCM10 CCDC14 25348397 N/A physical interaction ComPPI
MCM10 USP37 25348397 N/A physical interaction ComPPI
MCM10 YWHAE 25348397 N/A physical interaction ComPPI
MCM10 CAV3 25348397 N/A physical interaction ComPPI
MCM10 KLHL40 25348397 N/A physical interaction ComPPI
MCM10 TPH1 25348397 N/A physical interaction ComPPI
MCM10 CACNG5 25348397 N/A physical interaction ComPPI
MCM10 DAPK1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
IKZF5 MCM10 25348397 N/A physical interaction ComPPI
SGG MCM10 25348397 N/A pull down ComPPI
MCM10 IHOG 25348397 N/A anti tag coimmunoprecipitation ComPPI
MCM10 SU(VAR)205 12808023 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCM10 MCM10 17823614 24234451 N/A electron microscopy,molecular sieving IntAct
NCBP3 MCM10 24234451 26382858 association pull down IntAct
MCM10 RECQL4 19696745 27898060 inhibition N/A OmniPath
MCM10 POLA1 15494305 27898060 stimulant N/A OmniPath
IKBKG MCM10 20098747 27898060 N/A N/A OmniPath

Visualization










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