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GENE：EIF4E

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EIF4E
FullNmae eukaryotic translation initiation factor 4E
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3287
EnsembleID ENSG00000151247
Uniprot P06730

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EIF4E pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EIF4E mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EIF4E autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EIF4E GO:0000082,GO:0000339,GO:0000340,GO:0000340,GO:0000932,GO:0001662,GO:0003723,GO:0003743,GO:0003743,GO:0003743,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0005829,GO:0005845,GO:0006413,GO:0006417,GO:0010494,GO:0016281,GO:0016281,GO:0016281,GO:0016442,GO:0016607,GO:0017148,GO:0019827,GO:0019899,GO:0030182,GO:0031370,GO:0033391,GO:0036464,GO:0045665,GO:0045931,GO:0048471,GO:0051168,GO:0070062,GO:0071549,GO:0098794,GO:0098978,GO:0099578,GO:0140297

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EIF4E hsa:1977 path:hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human)
EIF4E hsa:1977 path:hsa04066 HIF-1 signaling pathway - Homo sapiens (human)
EIF4E hsa:1977 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
EIF4E hsa:1977 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
EIF4E hsa:1977 path:hsa04211 Longevity regulating pathway - Homo sapiens (human)
EIF4E hsa:1977 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MLST8 EIF4E 11108711 12150925 12408816 12709531 12844354 12867079 12906785 15314020 15755954 15905173 16286006 16469695 16679021 17368478 17680028 18391071 18492954 19022819 19339977 19568798 19597330 19864431 20647036 20932932 21157483 21177869 21233202 21981924 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MTOR EIF4E 11108711 12150925 12408816 12709531 12844354 12867079 12906785 15314020 15755954 15905173 16286006 16469695 16679021 17368478 17680028 18391071 18492954 19022819 19339977 19568798 19597330 19864431 20647036 20932932 21157483 21177869 21233202 21981924 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26192618 28216025 interaction type N/A ACSN
RPTOR EIF4E 11108711 12150925 12408816 12709531 12844354 12867079 12906785 15314020 15755954 15905173 16286006 16469695 16679021 17368478 17680028 18391071 18492954 19022819 19339977 19568798 19597330 19864431 20647036 20932932 21157483 21177869 21233202 21981924 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26192618 28216025 interaction type N/A ACSN
EIF4E EIF4B 12150925 12408816 12844354 12867079 12906785 15755954 15905173 16286006 16469695 16679021 17368478 17680028 18391071 18492954 19022819 19339977 19568798 19597330 19864431 20647036 21157483 21177869 21233202 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
EIF4E RPS6 12150925 12408816 12844354 12867079 12906785 15755954 15905173 16286006 16469695 16679021 17368478 17680028 18391071 18492954 19022819 19339977 19568798 19597330 19864431 20647036 21157483 21177869 21233202 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 28216025 interaction type N/A ACSN
MKNK1 EIF4E 10022874 11463832 18775330 23331499 26192618 9155017 9604935 9878069 interaction type,stimulation N/A ACSN,SignaLink
EIF4E HIF1A 10403805 11566883 12080085 12829734 13130303 15451019 15563472 16887934 1823643 26192618 7539918 8943284 9155017 9159130 9278421 9746763 9878069 interaction type N/A ACSN
PDCD4 EIF4E 12482958 17053147 17968323 17991735 18372920 19356152 23070007 26192618 interaction type N/A ACSN
EIF4E ETS1 15563472 26192618 9155017 9878069 interaction type N/A ACSN
EIF4EBP1 EIF4E 10022874 10330171 11605658 12482586 12604610 12747827 12867426 15153109 16189514 16242075 16271312 16467844 16648488 16824195 17316564 17353931 17689282 23180781 8521827 physical association affinity chromatography technology,anti tag coimmunoprecipitation,classical fluorescence spectroscopy,far western blotting,pull down,surface plasmon resonance,x-ray crystallography,two hybrid pooling approach InnateDB
EIF4E DDX3X 17667941 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
PML EIF4E 16189514 23180781 physical association two hybrid pooling approach InnateDB
EIF4E VCL 16189514 23180781 physical association two hybrid pooling approach InnateDB
EIF4E EIF4EBP2 15153109 16189514 16271312 17316564 23180781 physical association classical fluorescence spectroscopy,far western blotting,surface plasmon resonance,two hybrid pooling approach InnateDB
EIF4E EIF4G3 16189514 23180781 physical association two hybrid pooling approach InnateDB
EIF4ENIF1 EIF4E 16189514 23180781 physical association two hybrid pooling approach InnateDB
EIF4E ANKHD1 12482586 12588975 15153109 16189514 16271312 17316564 23180781 physical association affinity chromatography technology,classical fluorescence spectroscopy,far western blotting,pull down,surface plasmon resonance,two hybrid pooling approach InnateDB
EIF4E EIF4A2 17289916 17353931 23180781 29145629 8449919 physical association anti tag coimmunoprecipitation,inferred by curator InnateDB,Reactome
EIF4A1 EIF4E 17353931 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF4E EIF4G1 15153109 16467844 16648488 17689282 23180781 8521827 physical association affinity chromatography technology,anti tag coimmunoprecipitation,pull down InnateDB
EIF4E EIF4G2 16467844 17289916 23180781 29145629 physical association affinity chromatography technology,inferred by curator InnateDB,Reactome
EIF4E MKNK1 23180781 9878069 physical association anti tag coimmunoprecipitation InnateDB
MKNK2 EIF4E 11463832 12897141 23180781 23331499 9155017 phosphorylation reaction,stimulation protein kinase assay InnateDB,SignaLink
ELAVL1 EIF4E 15257295 19114552 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation InnateDB
HNRNPD EIF4E 15257295 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF4E EIF4A1 17289916 29145629 8449919 physical association inferred by curator Reactome
EIF4G3 EIF4E 17289916 29145629 physical association inferred by curator Reactome
EIF4E ARIH1 17289916 29145629 physical association inferred by curator Reactome
EIF4E2 EIF4E 17289916 29145629 physical association inferred by curator Reactome
EIF4E SMAD3 12150994 23331499 stimulation N/A SignaLink
EIF4E SMAD4 12150994 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR EIF4E 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 EIF4E 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 EIF4E 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC EIF4E 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 EIF4E 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 EIF4E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EIF4E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EIF4E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 EIF4E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EIF4E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EIF4E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 EIF4E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 EIF4E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 EIF4E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 EIF4E 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 EIF4E 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003E1A9 EIF4E 21238947 rna interference,inhibition western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00004F4657 EIF4E 21092188 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000003E1A9 EIF4E 21238947 25416803 mrna cleavage,inhibition western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00004F4657 EIF4E 21092188 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000017EA6A EIF4E 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004E008F EIF4E 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007D64A EIF4E 24845562 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000075AB14 EIF4E 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA EIF4E 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C EIF4E 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B EIF4E 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D EIF4E 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 EIF4E 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A EIF4E 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D EIF4E 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000913AC EIF4E 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D EIF4E 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 EIF4E 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 EIF4E 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A122A EIF4E 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005D4F5 EIF4E 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FF9C EIF4E 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C7B2B EIF4E 25416803 26250586 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000AD002 EIF4E 25416803 28350134 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
MKNK2 EIF4E 22135298 phosphorylation N/A PhosphoSite
MKNK1 EIF4E 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
EIF3H EIF4E 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
PAK2 EIF4E 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TDO2 EIF4E 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TRAF6 EIF4E 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PRKCA EIF4E 14525934 25348397 8662663 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
UBXN11 EIF4E 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SUMO1 EIF4E 20224576 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MAPKAPK5 EIF4E 14525934 25348397 9628874 N/A experimental interaction detection,in vitro ComPPI,HPRD
EIF4G1 EIF4E 15153109 15361857 18955708 20212144 21191102 23665581 24234451 25348397 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,pull down,physical interaction,in vitro,in vivo ComPPI,IntAct
RBM4 EIF4E 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
NTRK1 EIF4E 25348397 N/A physical interaction ComPPI
PRKCB EIF4E 14525934 25348397 8662663 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PABPC4 EIF4E 25348397 N/A physical interaction ComPPI
EIF4EBP1 EIF4E 10405182 10772338 11553333 11605658 12071973 14525934 15094042 15153109 16189514 16271312 16504179 16648488 16824195 17254965 17353931 18955708 19834456 20224576 20880835 21191102 22678294 24211447 24234451 25348397 25416956 7651417 7935836 8816458 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cosedimentation in solution,experimental interaction detection,far western blotting,filter binding,isothermal titration calorimetry,nuclear magnetic resonance,chromatography technology,pull down,surface plasmon resonance,physical interaction,two hybrid array,two hybrid pooling approach,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
MKNK2 EIF4E 12897141 14525934 25348397 9155017 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
EIF6 EIF4E 25348397 N/A physical interaction ComPPI
PPP2CA EIF4E 20927323 24234451 25348397 physical association anti bait coimmunoprecipitation,phosphatase assay ComPPI,IntAct
PRKCG EIF4E 14525934 25348397 8662663 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PABPC1 EIF4E 23665581 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3F EIF4E 25348397 N/A physical interaction ComPPI
CSK EIF4E 25348397 N/A physical interaction ComPPI
RPS6 EIF4E 18423201 18955708 24234451 25348397 association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
RPS6KB1 EIF4E 18423201 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GEMIN5 EIF4E 16739988 24234451 25348397 27898060 colocalization affinity chromatography technology,pull down,physical interaction,fluorescence microscopy ComPPI,IntAct,OmniPath
IRS1 EIF4E 23770097 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HSPA9 EIF4E 25348397 N/A physical interaction ComPPI
VCAM1 EIF4E 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
ITGA4 EIF4E 25348397 N/A physical interaction ComPPI
HIF1AN EIF4E 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX3X EIF4E 18596238 19262567 21883093 22872150 24234451 25348397 colocalization,association anti bait coimmunoprecipitation,cosedimentation,fluorescence microscopy,confocal microscopy ComPPI,IntAct
LRPPRC EIF4E 19262567 24234451 25348397 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
UPF1 EIF4E 23665581 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CYFIP1 EIF4E 18805096 24234451 25348397 27898060 N/A pull down ComPPI,IntAct,OmniPath
ASS1 EIF4E 25348397 N/A physical interaction ComPPI
NCBP1 EIF4E 23665581 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF4B EIF4E 14525934 2016328 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
EIF4G2 EIF4E 25348397 N/A in vitro ComPPI
EIF4A2 EIF4E 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MTOR EIF4E 18423201 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM27 EIF4E 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
STUB1 EIF4E 25348397 N/A physical interaction ComPPI
PML EIF4E 11500381 14525934 19262567 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
EIF4E EMX2 14525934 15247416 24234451 25348397 27898060 physical association affinity chromatography technology,coimmunoprecipitation,experimental interaction detection,pull down,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
EIF4E EIF4G3 14525934 25348397 9418880 N/A experimental interaction detection,nuclear magnetic resonance,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD
EIF4E EIF4ENIF1 10856257 14525934 16467844 19060904 24234451 25348397 25416956 colocalization,association,physical association affinity chromatography technology,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,two hybrid array,two hybrid pooling approach,imaging technique,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
EIF4E EIF4A1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF4E EIF3B 18423201 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF4E MKNK1 10022874 14525934 24234451 25348397 9155017 9878069 physical association coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
EIF4E DCC 25348397 N/A physical interaction ComPPI
EIF4E HSPB2 25348397 N/A physical interaction ComPPI
EIF4E RPTOR 25348397 N/A physical interaction ComPPI
EIF4E APP 25348397 N/A physical interaction ComPPI
EIF4E EIF4H 25348397 N/A physical interaction ComPPI
EIF4E CD83 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EIF4E AHSA1 25348397 N/A physical interaction ComPPI
EIF4E CAPN1 25348397 N/A physical interaction ComPPI
EIF4E NANS 25348397 N/A physical interaction ComPPI
EIF4E HSPD1 25348397 N/A physical interaction ComPPI
EIF4E PEPD 25348397 N/A physical interaction ComPPI
EIF4E PLPBP 25348397 N/A physical interaction ComPPI
EIF4E TYMP 25348397 N/A physical interaction ComPPI
EIF4E KANK2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EIF4E TRIM22 25348397 N/A physical interaction ComPPI
EIF4E ANGEL1 23814182 25348397 27898060 N/A physical interaction ComPPI,OmniPath
EIF4E DDX19A 25348397 N/A physical interaction ComPPI
EIF4E UBFD1 25348397 N/A physical interaction ComPPI
EIF4E PABPC3 25348397 N/A physical interaction ComPPI
EIF4E PDXK 25348397 N/A physical interaction ComPPI
EIF4E CYLD 25348397 N/A physical interaction ComPPI
EIF4E SMYD2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EIF4E INTS6 17469741 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF4E G3BP1 18005740 24234451 25348397 colocalization fluorescence technology ComPPI,IntAct
EIF4E NXF1 19262567 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF4E DDX39B 19262567 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF4E HNRNPA1 19262567 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF4E AGO2 20395958 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX19B EIF4E 25348397 N/A physical interaction ComPPI
EIF4EBP3 EIF4E 12482586 14525934 15153109 16271312 24234451 25348397 25416956 9593750 physical association coimmunoprecipitation,experimental interaction detection,far western blotting,pull down,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
EIF4EBP2 EIF4E 14525934 15153109 16271312 24207126 24234451 25348397 25416956 7651417 7935836 8939971 physical association experimental interaction detection,far western blotting,filter binding,isothermal titration calorimetry,nuclear magnetic resonance,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
PRDM4 EIF4E 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ECPAS EIF4E 25348397 N/A physical interaction ComPPI
EIF4E EIF4E 12482586 14525934 N/A experimental interaction detection HPRD
PRKCA EIF4E 1911648 2355012 27898060 8662663 stimulant N/A OmniPath
PRKCB EIF4E 27898060 8662663 N/A N/A OmniPath
ELAVL1 EIF4E 15257295 19114552 27898060 stimulant N/A OmniPath
MYC EIF4E 16915296 18593934 27898060 stimulant N/A OmniPath
WEE1 EIF4E 11723111 27898060 7782323 N/A N/A OmniPath
EIF4A1 EIF4E 16648488 17353931 22586265 27898060 N/A N/A OmniPath
EIF4E PML 11500381 11575918 12167712 12438698 16189514 27898060 N/A N/A OmniPath
PML EIF4E 11500381 11575918 12167712 12438698 16189514 27898060 N/A N/A OmniPath
PRKCG EIF4E 27898060 8662663 N/A N/A OmniPath
EIF4E EIF4G3 10394359 16189514 20212144 21191102 26186194 26344197 27898060 9418880 N/A N/A OmniPath
EIF4EBP1 EIF4E 10022874 10100614 10330171 10364159 10394359 10405182 10406811 10698949 10753870 10772338 11146653 11319880 11553333 11605658 12071973 12105188 12482586 12588975 12604610 12747827 12867426 15094042 15153109 15550948 15661536 15767663 16010989 16189514 16236269 16242075 16271312 16467844 16504179 16648488 16798736 16824195 17254965 17316564 17353931 17689282 18955708 18957614 19834456 20224576 20880835 21191102 21798997 22509910 22586265 22678294 23584478 24211447 24722188 25416956 26186194 26344197 27898060 7651417 7935836 8521827 8816458 9204908 inhibition N/A OmniPath
HNRNPD EIF4E 15257295 27898060 N/A N/A OmniPath
EIF4EBP3 EIF4E 10394359 11847216 12482586 15153109 15550948 16189514 16271312 24722188 25416956 27898060 7935836 9472019 9593750 inhibition,stimulant N/A OmniPath
EIF4E EIF4G2 10394359 10944120 16467844 27898060 N/A N/A OmniPath
EIF4G1 EIF4E 10600798 10753870 12071973 15153109 16010989 16236269 16281055 16467844 16541103 16648488 16720573 17689282 18955708 20212144 21191102 22509910 22586265 23665581 26186194 26344197 27898060 7651417 8521827 9372926 9418880 stimulant N/A OmniPath
EIF4EBP2 EIF4E 10406811 11847216 15153109 15550948 16189514 16271312 17316564 20347422 24207126 24722188 25416956 26186194 26344197 27898060 7651417 7935836 8939971 inhibition N/A OmniPath
PPP2CA EIF4E 20927323 27898060 inhibition N/A OmniPath
EIF4E SMAD4 12150994 27898060 stimulant N/A OmniPath
EIF4E SMAD3 12150994 27898060 stimulant N/A OmniPath
MKNK2 EIF4E 11154262 11463832 12897141 17724079 27898060 3112145 7665584 7782323 9155017 stimulant N/A OmniPath
ANKHD1 EIF4E 12482586 12588975 15153109 16189514 16271312 17316564 27898060 N/A N/A OmniPath
EIF4E MKNK1 10022874 11463832 27898060 9155017 9878069 N/A N/A OmniPath
MKNK1 EIF4E 10022874 11154262 11463832 11606200 11723111 15574771 16540463 16720573 17724079 20626350 21635931 25915158 25921059 25923732 27898060 7782323 9155017 9878069 stimulant N/A OmniPath
EIF4E EIF4ENIF1 10856257 16189514 16467844 19060904 24722188 25416956 26186194 27898060 N/A N/A OmniPath
EIF4ENIF1 EIF4E 10856257 16189514 16467844 19060904 24722188 25416956 26186194 27898060 N/A N/A OmniPath
VCL EIF4E 16189514 27898060 N/A N/A OmniPath
EIF4A2 EIF4E 17353931 27898060 stimulant N/A OmniPath
DDX3X EIF4E 17667941 18596238 21883093 22872150 27898060 N/A N/A OmniPath
CARD14 EIF4E 10022874 27898060 9155017 stimulant N/A OmniPath

Visualization










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