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GENE：EIF5A2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EIF5A2
FullNmae eukaryotic translation initiation factor 5A2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3301
EnsembleID ENSG00000163577
Uniprot Q9GZV4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EIF5A2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EIF5A2 GO:0003723,GO:0003746,GO:0005515,GO:0005634,GO:0005789,GO:0005829,GO:0006414,GO:0007283,GO:0043022,GO:0043231,GO:0045901,GO:0045905

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
OPTN EIF5A2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR EIF5A2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 EIF5A2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
MYC EIF5A2 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 EIF5A2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 EIF5A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EIF5A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EIF5A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EIF5A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 EIF5A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000600E6 EIF5A2 17242205 22473208 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS00000C85B2 EIF5A2 23622248 25416803 27292025 mrna cleavage,inhibition clip,clash TarBase
URS000008C563 EIF5A2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F EIF5A2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000321A1A EIF5A2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 EIF5A2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 EIF5A2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002E92A8 EIF5A2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC EIF5A2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 EIF5A2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F EIF5A2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075BEA7 EIF5A2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005A8ED EIF5A2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000033B91D EIF5A2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00005A8A8D EIF5A2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000054D341 EIF5A2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D EIF5A2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000040780F EIF5A2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 EIF5A2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 EIF5A2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 EIF5A2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA EIF5A2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 EIF5A2 25416803 26309359 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00005FDCD1 EIF5A2 25416803 26701625 27418678 mrna cleavage,inhibition clip TarBase
URS000003ABC4 EIF5A2 25416803 26701625 27418678 mrna cleavage,inhibition clip TarBase
URS000017CCCB EIF5A2 25416803 26701625 27418678 mrna cleavage,inhibition clip TarBase
URS00000C36BD EIF5A2 25416803 26701625 27418678 mrna cleavage,inhibition clip TarBase
URS000034E58D EIF5A2 25416803 26701625 27418678 mrna cleavage,inhibition clip TarBase
URS00001FA076 EIF5A2 25416803 26701625 27418678 mrna cleavage,inhibition clip TarBase
URS0000235862 EIF5A2 25416803 26701625 27418678 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 EIF5A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000B989F EIF5A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000039A052 EIF5A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000021202F EIF5A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075CC78 EIF5A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075D814 EIF5A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001012BC EIF5A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000045147B EIF5A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001A7F58 EIF5A2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000383DF4 EIF5A2 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DHPS EIF5A2 25361965 interaction type N/A PTMCode2
EIF5A2 DHPS 25361965 interaction type N/A PTMCode2
DOHH EIF5A2 25361965 interaction type N/A PTMCode2
EIF5A2 DOHH 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EIF5A2 DHPS 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
EIF5A2 DCC 20434207 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF5A2 OPTN 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF5A2 VHL 25348397 N/A physical interaction ComPPI
EIF5A2 CUL3 25348397 N/A physical interaction ComPPI
EIF5A2 CUL4B 25348397 N/A physical interaction ComPPI
EIF5A2 CDK2 25348397 N/A physical interaction ComPPI
EIF5A2 RAB30 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EIF5A2 PTBP2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EIF5A2 CIAO2B 25348397 N/A physical interaction ComPPI
EIF5A2 REL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EIF5A2 SDCBP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EIF5A2 CDC23 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EIF5A2 NIF3L1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EIF5A2 DOHH 25348397 N/A physical interaction ComPPI
EIF5A2 EZR 25348397 N/A physical interaction ComPPI
EIF5A2 PPIB 25348397 N/A physical interaction ComPPI
EIF5A2 MYCBP 25348397 N/A physical interaction ComPPI
EIF5A2 TAGLN2 25348397 N/A physical interaction ComPPI
EIF5A2 EWSR1 25348397 N/A physical interaction ComPPI
EIF5A2 MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EIF5A2 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct

Visualization










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