GENE:GABPA
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | GABPA |
| FullNmae | GA binding protein transcription factor subunit alpha |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:4071 |
| EnsembleID | ENSG00000154727 |
| Uniprot | Q06546 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| GABPA | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| GABPA | GO:0000122,GO:0000785,GO:0000785,GO:0000976,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0001825,GO:0003682,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0006357,GO:0030154,GO:0045653,GO:0045944,GO:1990837 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GABPA | IL16 | 18097041 23180781 9990060 | physical association | anti tag coimmunoprecipitation,electrophoretic mobility supershift assay | InnateDB |
| GABPA | EP300 | 23180781 9990060 | physical association | pull down | InnateDB |
| IL16 | GABPA | 18097041 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| SKP2 | GABPA | 18097041 23180781 | physical association | electrophoretic mobility supershift assay | InnateDB |
| GABPA | GABPB1 | 18097041 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| GABPA | SKP2 | 12907639 18097041 23180781 | physical association | anti tag coimmunoprecipitation,electrophoretic mobility supershift assay | InnateDB |
| GABPA | HDAC3 | 18097041 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| GABPA | ITGAX | 23180781 9295016 | physical association | electrophoretic mobility supershift assay | InnateDB |
| GABPA | EGR1 | 19374776 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| GABPA | KIR3DL1 | 16818466 23180781 | physical association | electrophoretic mobility supershift assay | InnateDB |
| GABPA | CEBPB | 15928042 23180781 | physical association | pull down | InnateDB |
| GABPA | FCER1G | 18378679 23180781 | physical association | anti tag coimmunoprecipitation,electrophoretic mobility supershift assay | InnateDB |
| GABPA | GABPA | 15928042 23180781 | physical association | pull down | InnateDB |
| APP | GABPA | 21832049 23180781 | physical association | protein array | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | GABPA | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | GABPA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | GABPA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | GABPA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | GABPA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | GABPA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | GABPA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | GABPA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ATF1 | GABPA | 10585419 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CREB1 | GABPA | 10585419 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000035CC3E | GABPA | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS0000171CD1 | GABPA | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | GABPA | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | GABPA | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | GABPA | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | GABPA | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000451A1 | GABPA | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005606AA | GABPA | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HCFC1 | GABPA | 25361965 | interaction type | N/A | PTMCode2 |
| GABPA | HCFC1 | 25361965 | interaction type | N/A | PTMCode2 |
| GABPA | GABPB2 | 25361965 | interaction type | N/A | PTMCode2 |
| GABPB2 | GABPA | 25361965 | interaction type | N/A | PTMCode2 |
| GABPA | GABPB1 | 25361965 | interaction type | N/A | PTMCode2 |
| GABPB1 | GABPA | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| STK16 | GABPA | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TPD52L2 | GABPA | 25348397 | N/A | physical interaction | ComPPI |
| KPNA1 | GABPA | 25348397 | N/A | physical interaction | ComPPI |
| GABPB1 | GABPA | 11953439 14525934 22939629 24234451 25348397 26186194 26344197 27898060 8441384 9016666 9461436 9792629 | physical association | two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach | ComPPI,HPRD,IntAct,OmniPath |
| KEAP1 | GABPA | 25348397 | N/A | physical interaction | ComPPI |
| SP1 | GABPA | 11237613 14525934 24234451 25348397 | physical association | anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro | ComPPI,HPRD,IntAct |
| HCFC1 | GABPA | 10675337 14525934 24234451 25348397 | association,physical association | two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid | ComPPI,HPRD,IntAct |
| CREBBP | GABPA | 14525934 25348397 9990060 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| EP300 | GABPA | 14525934 25348397 9990060 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| FHL2 | GABPA | 16624878 24234451 25348397 | N/A | pull down,physical interaction | ComPPI,IntAct |
| MED1 | GABPA | 16574658 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| SP3 | GABPA | 11237613 14525934 24234451 25348397 | physical association | anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo | ComPPI,HPRD,IntAct |
| YY1 | GABPA | 25348397 | N/A | physical interaction | ComPPI |
| PINX1 | GABPA | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| GABPA | ATF1 | 10585419 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| GABPA | HDAC1 | 25348397 | N/A | physical interaction | ComPPI |
| GABPA | APP | 25348397 | N/A | physical interaction | ComPPI |
| GABPA | DIABLO | 25348397 | N/A | physical interaction | ComPPI |
| GABPA | GNE | 25348397 | N/A | physical interaction | ComPPI |
| GABPA | KCTD12 | 25348397 | N/A | physical interaction | ComPPI |
| GABPA | LIMCH1 | 25348397 | N/A | physical interaction | ComPPI |
| GABPA | NCOA7 | 25348397 | N/A | physical interaction | ComPPI |
| GABPA | RAB3GAP1 | 25348397 | N/A | physical interaction | ComPPI |
| GABPA | RAB3GAP2 | 25348397 | N/A | physical interaction | ComPPI |
| GABPA | TSEN34 | 25348397 | N/A | physical interaction | ComPPI |
| GABPA | YEATS4 | 25348397 | N/A | physical interaction | ComPPI |
| GABPA | FOXJ2 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| GABPA | ADGRB2 | 16412436 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| GABPA | ZC2HC1B | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CUTC | GABPA | 25348397 | N/A | physical interaction | ComPPI |
| GABPB2 | GABPA | 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| GABPA | SKP2 | 12907639 27898060 | N/A | N/A | OmniPath |
| CEBPB | GABPA | 15928042 27898060 | N/A | N/A | OmniPath |
| GABPA | TXN | 19114066 27898060 | stimulant | N/A | OmniPath |
| MAPK3 | GABPA | 19114066 27898060 | stimulant | N/A | OmniPath |
| GABPA | TXNRD1 | 19114066 27898060 | stimulant | N/A | OmniPath |
| GABPA | EP300 | 16581781 17304221 27898060 9990060 | N/A | N/A | OmniPath |
| MAPK1 | GABPA | 19114066 27898060 | stimulant | N/A | OmniPath |
| KEAP1 | GABPA | 17439941 19114066 19424503 27898060 | inhibition | N/A | OmniPath |
