Gene Information gene info

GENE:GABPA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GABPA
FullNmae GA binding protein transcription factor subunit alpha
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4071
EnsembleID ENSG00000154727
Uniprot Q06546

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GABPA autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GABPA GO:0000122,GO:0000785,GO:0000785,GO:0000976,GO:0000978,GO:0000981,GO:0000981,GO:0001228,GO:0001825,GO:0003682,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0006357,GO:0030154,GO:0045653,GO:0045944,GO:1990837

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GABPA IL16 18097041 23180781 9990060 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
GABPA EP300 23180781 9990060 physical association pull down InnateDB
IL16 GABPA 18097041 23180781 physical association anti tag coimmunoprecipitation InnateDB
SKP2 GABPA 18097041 23180781 physical association electrophoretic mobility supershift assay InnateDB
GABPA GABPB1 18097041 23180781 physical association anti tag coimmunoprecipitation InnateDB
GABPA SKP2 12907639 18097041 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
GABPA HDAC3 18097041 23180781 physical association anti tag coimmunoprecipitation InnateDB
GABPA ITGAX 23180781 9295016 physical association electrophoretic mobility supershift assay InnateDB
GABPA EGR1 19374776 23180781 physical association anti tag coimmunoprecipitation InnateDB
GABPA KIR3DL1 16818466 23180781 physical association electrophoretic mobility supershift assay InnateDB
GABPA CEBPB 15928042 23180781 physical association pull down InnateDB
GABPA FCER1G 18378679 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
GABPA GABPA 15928042 23180781 physical association pull down InnateDB
APP GABPA 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 GABPA 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 GABPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GABPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GABPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GABPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 GABPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 GABPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 GABPA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ATF1 GABPA 10585419 trascriptional regulation,stimulation inferred by curator TFlink
CREB1 GABPA 10585419 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000035CC3E GABPA 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000171CD1 GABPA 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C GABPA 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D GABPA 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 GABPA 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A GABPA 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 GABPA 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA GABPA 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HCFC1 GABPA 25361965 interaction type N/A PTMCode2
GABPA HCFC1 25361965 interaction type N/A PTMCode2
GABPA GABPB2 25361965 interaction type N/A PTMCode2
GABPB2 GABPA 25361965 interaction type N/A PTMCode2
GABPA GABPB1 25361965 interaction type N/A PTMCode2
GABPB1 GABPA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
STK16 GABPA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TPD52L2 GABPA 25348397 N/A physical interaction ComPPI
KPNA1 GABPA 25348397 N/A physical interaction ComPPI
GABPB1 GABPA 11953439 14525934 22939629 24234451 25348397 26186194 26344197 27898060 8441384 9016666 9461436 9792629 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct,OmniPath
KEAP1 GABPA 25348397 N/A physical interaction ComPPI
SP1 GABPA 11237613 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
HCFC1 GABPA 10675337 14525934 24234451 25348397 association,physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
CREBBP GABPA 14525934 25348397 9990060 N/A experimental interaction detection,in vitro ComPPI,HPRD
EP300 GABPA 14525934 25348397 9990060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
FHL2 GABPA 16624878 24234451 25348397 N/A pull down,physical interaction ComPPI,IntAct
MED1 GABPA 16574658 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SP3 GABPA 11237613 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
YY1 GABPA 25348397 N/A physical interaction ComPPI
PINX1 GABPA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GABPA ATF1 10585419 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GABPA HDAC1 25348397 N/A physical interaction ComPPI
GABPA APP 25348397 N/A physical interaction ComPPI
GABPA DIABLO 25348397 N/A physical interaction ComPPI
GABPA GNE 25348397 N/A physical interaction ComPPI
GABPA KCTD12 25348397 N/A physical interaction ComPPI
GABPA LIMCH1 25348397 N/A physical interaction ComPPI
GABPA NCOA7 25348397 N/A physical interaction ComPPI
GABPA RAB3GAP1 25348397 N/A physical interaction ComPPI
GABPA RAB3GAP2 25348397 N/A physical interaction ComPPI
GABPA TSEN34 25348397 N/A physical interaction ComPPI
GABPA YEATS4 25348397 N/A physical interaction ComPPI
GABPA FOXJ2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
GABPA ADGRB2 16412436 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GABPA ZC2HC1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CUTC GABPA 25348397 N/A physical interaction ComPPI
GABPB2 GABPA 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GABPA SKP2 12907639 27898060 N/A N/A OmniPath
CEBPB GABPA 15928042 27898060 N/A N/A OmniPath
GABPA TXN 19114066 27898060 stimulant N/A OmniPath
MAPK3 GABPA 19114066 27898060 stimulant N/A OmniPath
GABPA TXNRD1 19114066 27898060 stimulant N/A OmniPath
GABPA EP300 16581781 17304221 27898060 9990060 N/A N/A OmniPath
MAPK1 GABPA 19114066 27898060 stimulant N/A OmniPath
KEAP1 GABPA 17439941 19114066 19424503 27898060 inhibition N/A OmniPath

Visualization