Gene Information gene info

GENE:PPL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PPL
FullNmae periplakin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9273
EnsembleID ENSG00000118898
Uniprot O60437

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PPL autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PPL GO:0001533,GO:0005198,GO:0005200,GO:0005515,GO:0005737,GO:0005737,GO:0005829,GO:0005856,GO:0005882,GO:0005886,GO:0009612,GO:0016020,GO:0030057,GO:0031424,GO:0042060,GO:0045104,GO:0045296,GO:0070062

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ALAS1 PPL 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 PPL 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 PPL 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 PPL 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PPL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 PPL 19583808 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 PPL 19583808 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A PPL N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 PPL N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 PPL 18668040 22815788 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr TarBase
URS0000237AF9 PPL 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000021D7C8 PPL 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000321A1A PPL 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000007340 PPL 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B PPL 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 PPL 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD PPL 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5E03 PPL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000060B2B PPL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E177F PPL 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000033EBB8 PPL 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EVPL PPL 25361965 interaction type N/A PTMCode2
PPL EVPL 25361965 interaction type N/A PTMCode2
PPHLN1 PPL 25361965 interaction type N/A PTMCode2
PPL PPHLN1 25361965 interaction type N/A PTMCode2
KRT8 PPL 25361965 interaction type N/A PTMCode2
PPL KRT8 25361965 interaction type N/A PTMCode2
CASP6 PPL 25361965 interaction type N/A PTMCode2
PPL CASP6 25361965 interaction type N/A PTMCode2
EZR PPL 25361965 interaction type N/A PTMCode2
PPL EZR 25361965 interaction type N/A PTMCode2
AKT1 PPL 25361965 interaction type N/A PTMCode2
PPL AKT1 25361965 interaction type N/A PTMCode2
PPL COL17A1 25361965 interaction type N/A PTMCode2
COL17A1 PPL 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ZNF165 PPL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TBC1D22B PPL 25348397 N/A physical interaction ComPPI
PDE4DIP PPL 25348397 N/A physical interaction ComPPI
PPL VIM 12366696 14525934 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
PPL RALBP1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPL CASP6 14525934 15654952 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PPL EVPL 11062259 12432088 14525934 25348397 27898060 9412476 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
PPL COL17A1 14525934 25348397 27898060 9521878 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD,OmniPath
PPL PPHLN1 12853457 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
PPL KAZN 15337775 25348397 27898060 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI,OmniPath
PPL USP7 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PPL OPRM1 12810704 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
PPL SKIL 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PPL AKT1 12176997 12244133 14525934 18624398 24234451 25348397 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PPL EZR 25348397 N/A physical interaction ComPPI
PPL KRT8 22841549 24234451 25348397 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct
PPL ITSN1 25348397 N/A physical interaction ComPPI
PPL CUL1 25348397 N/A physical interaction ComPPI
PPL UBC 25348397 N/A physical interaction ComPPI
PPL ALAS1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPL TRIM27 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPL TRAF2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPL AHCYL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPL TSC22D4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPL RAB3IP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPL ZSCAN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPL CEP57L1 25348397 N/A physical interaction ComPPI
PPL SUSD3 25348397 N/A physical interaction ComPPI
PPL DDX19B 25348397 N/A physical interaction ComPPI
PPL KIR3DS1 25348397 N/A physical interaction ComPPI
PPL UGT1A10 25348397 N/A physical interaction ComPPI
PPL ZSCAN20 25348397 N/A physical interaction ComPPI
PPL RBM24 25348397 N/A physical interaction ComPPI
PPL HNRNPA1 25348397 N/A physical interaction ComPPI
PPL DROSHA 25348397 N/A physical interaction ComPPI
PPL P4HA2 25348397 N/A physical interaction ComPPI
PPL PSMA1 25348397 N/A physical interaction ComPPI
PPL PSMA5 25348397 N/A physical interaction ComPPI
PPL PSMB4 25348397 N/A physical interaction ComPPI
PPL PSMB6 25348397 N/A physical interaction ComPPI
PPL PTEN 25348397 N/A physical interaction ComPPI
PPL RBM4 25348397 N/A physical interaction ComPPI
PPL SYNPO 25348397 N/A physical interaction ComPPI
PPL FYCO1 25348397 N/A physical interaction ComPPI
PPL INTS14 25348397 N/A physical interaction ComPPI
PPL CDH1 25348397 N/A physical interaction ComPPI
PPL FCF1 25348397 N/A physical interaction ComPPI
PPL CDK15 25348397 N/A physical interaction ComPPI
PPL FRMD1 25348397 N/A physical interaction ComPPI
PPL CCNYL1 25348397 N/A physical interaction ComPPI
PPL FTH1 25348397 N/A physical interaction ComPPI
PPL ACAD9 25348397 N/A physical interaction ComPPI
PPL TNFRSF19 25348397 N/A physical interaction ComPPI
PPL WRAP73 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PPL ANXA9 22841549 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,fluorescence microscopy ComPPI,IntAct
PPL HTT 17500595 24234451 25348397 physical association two hybrid ComPPI,IntAct
PPL MRPL28 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL ZSCAN16 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL ZNF263 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL ZNF213 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL UPRT 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL ZBTB26 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL ACTR5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL C6ORF141 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL DES 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL PBX4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL SDCBP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL HECTD3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL KNSTRN 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL KCTD21 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL ZNF474 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL PICK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL KRT25 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL KRT39 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPL BTN3A1 24234451 25348397 25637025 physical association anti tag coimmunoprecipitation,two hybrid,isothermal titration calorimetry,pull down ComPPI,IntAct
PPL BTN1A1 24234451 25348397 25637025 physical association anti tag coimmunoprecipitation ComPPI,IntAct
PPL PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
LETM1 PPL 24234451 30021884 physical association cross-linking study IntAct
HNRNPM PPL 24234451 30021884 physical association cross-linking study IntAct

Visualization