Gene Information gene info

GENE:CNOT6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CNOT6
FullNmae CCR4-NOT transcription complex subunit 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14099
EnsembleID ENSG00000113300
Uniprot Q9ULM6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CNOT6 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CNOT6 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CNOT6 GO:0000289,GO:0000289,GO:0000289,GO:0000289,GO:0003723,GO:0004532,GO:0004535,GO:0004535,GO:0004535,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0008284,GO:0010606,GO:0016020,GO:0030014,GO:0030014,GO:0030014,GO:0030374,GO:0035195,GO:0043928,GO:0045893,GO:0046872,GO:0070966

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CNOT6 hsa:57472 path:hsa03018 RNA degradation - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 CNOT6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 CNOT6 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 CNOT6 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 CNOT6 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 CNOT6 20554955 21036387 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
PRDM14 CNOT6 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CNOT6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CNOT6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CNOT6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CNOT6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CNOT6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CNOT6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 CNOT6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CNOT6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOSL2 CNOT6 22493372 trascriptional regulation,stimulation inferred by curator TFlink
JUND CNOT6 22493372 trascriptional regulation,stimulation inferred by curator TFlink
TBX21 CNOT6 14500650 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CNOT2 CNOT6 25361965 interaction type N/A PTMCode2
CNOT6 CNOT2 25361965 interaction type N/A PTMCode2
CNOT6 CNOT8 25361965 interaction type N/A PTMCode2
CNOT8 CNOT6 25361965 interaction type N/A PTMCode2
CNOT6 PABPC1 25361965 interaction type N/A PTMCode2
PABPC1 CNOT6 25361965 interaction type N/A PTMCode2
CNOT6 CNOT7 25361965 interaction type N/A PTMCode2
CNOT7 CNOT6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NANOS2 CNOT6 25348397 N/A physical interaction ComPPI
MMP7 CNOT6 25348397 N/A physical interaction ComPPI
TOB1 CNOT6 25348397 N/A physical interaction ComPPI
GADD45B CNOT6 25348397 N/A physical interaction ComPPI
HSP90AA1 CNOT6 19875381 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CHAF1A CNOT6 25348397 N/A physical interaction ComPPI
ZFP36 CNOT6 25348397 N/A physical interaction ComPPI
PABPC1 CNOT6 25348397 N/A physical interaction ComPPI
ATXN3 CNOT6 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
NFKB1 CNOT6 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ELAVL1 CNOT6 25348397 N/A physical interaction ComPPI
CNOT7 CNOT6 11747467 24234451 25348397 physical association two hybrid,far western blotting,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CNOT8 CNOT6 11747467 17452450 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid ComPPI,IntAct
TNKS1BP1 CNOT6 17452450 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CNOT1 CNOT6 17452450 22977175 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CNOT2 CNOT6 17452450 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
CNOT3 CNOT6 17452450 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT6 HSP90AA2P 25348397 N/A physical interaction ComPPI
CNOT6 CNOT9 17452450 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT6 CNOT10 17452450 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CNOT6 TNRC6C 21981923 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT6 ZMAT3 25348397 N/A physical interaction ComPPI
CNOT6 CAPZA2 25348397 N/A physical interaction ComPPI
CNOT6 TNRC6A 21981923 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT6 TNRC6B 21981923 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT6 AGO2 21981923 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CNOT6 ZFP36L1 25348397 N/A physical interaction ComPPI
CNOT6 CNOT11 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CNOT6 RIBC1 25348397 N/A physical interaction ComPPI
CNOT6 IZUMO1 25348397 N/A physical interaction ComPPI
CNOT6 CNOT6L 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
CNOT6 GLA 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TEX13A CNOT6 25348397 N/A physical interaction ComPPI

Visualization