GENE:CNOT6
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | CNOT6 |
FullNmae | CCR4-NOT transcription complex subunit 6 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:14099 |
EnsembleID | ENSG00000113300 |
Uniprot | Q9ULM6 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
CNOT6 | parthanatos | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
CNOT6 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
CNOT6 | GO:0000289,GO:0000289,GO:0000289,GO:0000289,GO:0003723,GO:0004532,GO:0004535,GO:0004535,GO:0004535,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0008284,GO:0010606,GO:0016020,GO:0030014,GO:0030014,GO:0030014,GO:0030374,GO:0035195,GO:0043928,GO:0045893,GO:0046872,GO:0070966 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
CNOT6 | hsa:57472 | path:hsa03018 | RNA degradation - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | CNOT6 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA3 | CNOT6 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXA1 | CNOT6 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
YBX1 | CNOT6 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXP3 | CNOT6 | 20554955 21036387 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
PRDM14 | CNOT6 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | CNOT6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | CNOT6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | CNOT6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | CNOT6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | CNOT6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | CNOT6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | CNOT6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | CNOT6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOSL2 | CNOT6 | 22493372 | trascriptional regulation,stimulation | inferred by curator | TFlink |
JUND | CNOT6 | 22493372 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TBX21 | CNOT6 | 14500650 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
CNOT2 | CNOT6 | 25361965 | interaction type | N/A | PTMCode2 |
CNOT6 | CNOT2 | 25361965 | interaction type | N/A | PTMCode2 |
CNOT6 | CNOT8 | 25361965 | interaction type | N/A | PTMCode2 |
CNOT8 | CNOT6 | 25361965 | interaction type | N/A | PTMCode2 |
CNOT6 | PABPC1 | 25361965 | interaction type | N/A | PTMCode2 |
PABPC1 | CNOT6 | 25361965 | interaction type | N/A | PTMCode2 |
CNOT6 | CNOT7 | 25361965 | interaction type | N/A | PTMCode2 |
CNOT7 | CNOT6 | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
NANOS2 | CNOT6 | 25348397 | N/A | physical interaction | ComPPI |
MMP7 | CNOT6 | 25348397 | N/A | physical interaction | ComPPI |
TOB1 | CNOT6 | 25348397 | N/A | physical interaction | ComPPI |
GADD45B | CNOT6 | 25348397 | N/A | physical interaction | ComPPI |
HSP90AA1 | CNOT6 | 19875381 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
CHAF1A | CNOT6 | 25348397 | N/A | physical interaction | ComPPI |
ZFP36 | CNOT6 | 25348397 | N/A | physical interaction | ComPPI |
PABPC1 | CNOT6 | 25348397 | N/A | physical interaction | ComPPI |
ATXN3 | CNOT6 | 25348397 | N/A | anti tag coimmunoprecipitation,physical interaction | ComPPI |
NFKB1 | CNOT6 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
ELAVL1 | CNOT6 | 25348397 | N/A | physical interaction | ComPPI |
CNOT7 | CNOT6 | 11747467 24234451 25348397 | physical association | two hybrid,far western blotting,physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
CNOT8 | CNOT6 | 11747467 17452450 24234451 25348397 | physical association | anti tag coimmunoprecipitation,two hybrid | ComPPI,IntAct |
TNKS1BP1 | CNOT6 | 17452450 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
CNOT1 | CNOT6 | 17452450 22977175 24234451 25348397 26496610 | association,physical association | anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
CNOT2 | CNOT6 | 17452450 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring | ComPPI,IntAct |
CNOT3 | CNOT6 | 17452450 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CNOT6 | HSP90AA2P | 25348397 | N/A | physical interaction | ComPPI |
CNOT6 | CNOT9 | 17452450 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CNOT6 | CNOT10 | 17452450 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
CNOT6 | TNRC6C | 21981923 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CNOT6 | ZMAT3 | 25348397 | N/A | physical interaction | ComPPI |
CNOT6 | CAPZA2 | 25348397 | N/A | physical interaction | ComPPI |
CNOT6 | TNRC6A | 21981923 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CNOT6 | TNRC6B | 21981923 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CNOT6 | AGO2 | 21981923 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CNOT6 | ZFP36L1 | 25348397 | N/A | physical interaction | ComPPI |
CNOT6 | CNOT11 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
CNOT6 | RIBC1 | 25348397 | N/A | physical interaction | ComPPI |
CNOT6 | IZUMO1 | 25348397 | N/A | physical interaction | ComPPI |
CNOT6 | CNOT6L | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
CNOT6 | GLA | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
TEX13A | CNOT6 | 25348397 | N/A | physical interaction | ComPPI |