Gene Information gene info

  1. Home

GENE：ARHGEF7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ARHGEF7
FullNmae Rho guanine nucleotide exchange factor 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15607
EnsembleID ENSG00000102606
Uniprot Q14155

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ARHGEF7 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ARHGEF7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ARHGEF7 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ARHGEF7 GO:0001726,GO:0005085,GO:0005085,GO:0005085,GO:0005515,GO:0005737,GO:0005813,GO:0005829,GO:0005925,GO:0005938,GO:0007030,GO:0007165,GO:0007399,GO:0010763,GO:0019901,GO:0030027,GO:0030027,GO:0030032,GO:0030032,GO:0032991,GO:0035556,GO:0043005,GO:0043015,GO:0043025,GO:0043065,GO:0043547,GO:0043547,GO:0048013,GO:0048041,GO:0097431,GO:0098794,GO:1900026,GO:1904424,GO:1905833,GO:2000394

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ARHGEF7 hsa:8874 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
ARHGEF7 hsa:8874 path:hsa05135 Yersinia infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ARHGEF7 PAK1 17392278 23180781 phosphorylation reaction anti tag coimmunoprecipitation,protein kinase assay InnateDB
ERBIN ARHGEF7 15123239 23180781 physical association peptide array InnateDB
ARHGEF7 SHC1 18385518 23180781 physical association anti tag coimmunoprecipitation InnateDB
RAC1 ARHGEF7 18684957 23180781 physical association anti tag coimmunoprecipitation InnateDB
NOD2 ARHGEF7 18684957 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
CDC42 ARHGEF7 14505571 15649357 16983070 18988627 20542890 inhibition N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR ARHGEF7 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ARHGEF7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 ARHGEF7 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
TP53 ARHGEF7 15843459 trascriptional regulation,stimulation inferred by curator TFlink
SMARCA4 ARHGEF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ARHGEF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ARHGEF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ARHGEF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ARHGEF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ARHGEF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ARHGEF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 ARHGEF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ARHGEF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ARHGEF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 ARHGEF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ARHGEF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ARHGEF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000035CC3E ARHGEF7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F ARHGEF7 22473208 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00002075FA ARHGEF7 22473208 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS0000076E54 ARHGEF7 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 ARHGEF7 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000098B3B ARHGEF7 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 ARHGEF7 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 ARHGEF7 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 ARHGEF7 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKCG ARHGEF7 22135298 phosphorylation N/A PhosphoSite
NCK1 ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 NCK1 25361965 interaction type N/A PTMCode2
CBLB ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 CBLB 25361965 interaction type N/A PTMCode2
CBL ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 CBL 25361965 interaction type N/A PTMCode2
AXL ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 AXL 25361965 interaction type N/A PTMCode2
GAB1 ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 GAB1 25361965 interaction type N/A PTMCode2
RAC1 ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 RAC1 25361965 interaction type N/A PTMCode2
EZR ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 EZR 25361965 interaction type N/A PTMCode2
SCRIB ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 SCRIB 25361965 interaction type N/A PTMCode2
ARHGEF7 RELA 25361965 interaction type N/A PTMCode2
RELA ARHGEF7 25361965 interaction type N/A PTMCode2
ERBB3 ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 ERBB3 25361965 interaction type N/A PTMCode2
LTK ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 LTK 25361965 interaction type N/A PTMCode2
PIK3R1 ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 PIK3R1 25361965 interaction type N/A PTMCode2
REL ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 REL 25361965 interaction type N/A PTMCode2
NFKB1 ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 NFKB1 25361965 interaction type N/A PTMCode2
SHANK1 ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 SHANK1 25361965 interaction type N/A PTMCode2
CDC42 ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 CDC42 25361965 interaction type N/A PTMCode2
ERBB4 ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 ERBB4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NCK2 ARHGEF7 25348397 N/A physical interaction ComPPI
CDC42 ARHGEF7 14525934 15649357 16983070 25348397 N/A anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD
PAK2 ARHGEF7 12226077 14525934 16374509 16787945 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,filter binding,phage display,physical interaction,competition binding,in vitro,in vivo ComPPI,HPRD,IntAct
PPP2R1A ARHGEF7 24234451 25150978 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WAS ARHGEF7 14525934 14559906 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MEOX2 ARHGEF7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
YWHAG ARHGEF7 14525934 15324660 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
CALM1 ARHGEF7 25348397 N/A physical interaction ComPPI
SKP1 ARHGEF7 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
RAC1 ARHGEF7 14525934 14557270 16492808 24234451 24792722 25348397 physical association experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
PAK1 ARHGEF7 16101281 16407834 16492808 16628223 20936779 23455922 24234451 25348397 29997244 association,physical association anti bait coimmunoprecipitation,bioluminescence resonance energy transfer,classical fluorescence spectroscopy,nuclear magnetic resonance,pull down,physical interaction,two hybrid pooling approach,in vitro,in vivo,tandem affinity purification,luminescence based mammalian interactome mapping ComPPI,IntAct
ERBIN ARHGEF7 25348397 N/A physical interaction ComPPI
CBL ARHGEF7 16407834 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
TGFBR2 ARHGEF7 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CBLB ARHGEF7 12935897 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
NCK1 ARHGEF7 10330411 14525934 14559906 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
GRB2 ARHGEF7 25348397 N/A physical interaction ComPPI
SMAD3 ARHGEF7 25348397 N/A tandem affinity purification ComPPI
SRGAP1 ARHGEF7 24234451 25150978 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 ARHGEF7 25348397 N/A physical interaction ComPPI
GIT1 ARHGEF7 10896954 14525934 16628223 16787945 21295525 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PXN ARHGEF7 25348397 N/A in vitro ComPPI
CASK ARHGEF7 15975580 24234451 25348397 physical association pull down ComPPI,IntAct
EXOC1 ARHGEF7 25348397 N/A physical interaction ComPPI
SHANK1 ARHGEF7 12626503 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
NAA10 ARHGEF7 21295525 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
EGFR ARHGEF7 24234451 24658140 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
SH2D1A ARHGEF7 14525934 16983070 24234451 25348397 25416956 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,mammalian protein protein interaction trap,in vivo,two hybrid ComPPI,HPRD,IntAct
ADAM15 ARHGEF7 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,physical interaction,in vitro ComPPI,HPRD,IntAct
HSPB1 ARHGEF7 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
ITCH ARHGEF7 17652093 25348397 26613292 27898060 N/A physical interaction ComPPI,OmniPath
NCKIPSD ARHGEF7 14525934 14559906 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
LPXN ARHGEF7 25348397 N/A physical interaction ComPPI
CERS2 ARHGEF7 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
PAK3 ARHGEF7 14525934 25348397 9726964 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ARHGEF6 ARHGEF7 12499396 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
ARHGEF7 GIT2 10428811 10896954 14525934 16628223 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
ARHGEF7 PPM1F 11864573 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ARHGEF7 TUBB3 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
ARHGEF7 SCRIB 15182672 15975580 19041750 19555689 21132015 24234451 24550280 25348397 27898060 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,phage display,pull down,physical interaction,fluorescence microscopy,in vitro,in vivo ComPPI,IntAct,OmniPath
ARHGEF7 CD244 14525934 16983070 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
ARHGEF7 SHANK2 12626503 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
ARHGEF7 SHANK3 25348397 N/A physical interaction ComPPI
ARHGEF7 MC1R 25348397 N/A physical interaction ComPPI
ARHGEF7 PPM1E 25348397 N/A physical interaction ComPPI
ARHGEF7 LRRK2 21048939 24234451 25348397 25500533 phosphorylation reaction,colocalization,gtpase reaction,association,physical association anti tag coimmunoprecipitation,physical interaction,gtpase assay,protein kinase assay,confocal microscopy ComPPI,IntAct
ARHGEF7 KDM2A 25348397 N/A physical interaction ComPPI
ARHGEF7 MED4 25348397 N/A physical interaction ComPPI
ARHGEF7 SLC33A1 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
ARHGEF7 FBXO28 25348397 N/A physical interaction ComPPI
ARHGEF7 ICAM1 25348397 N/A physical interaction ComPPI
ARHGEF7 KLHL2 25348397 N/A physical interaction ComPPI
ARHGEF7 CAMK4 25348397 N/A physical interaction ComPPI
ARHGEF7 SYNC 25348397 N/A physical interaction ComPPI
ARHGEF7 INAVA 25348397 N/A physical interaction ComPPI
ARHGEF7 POTEB3 25348397 N/A physical interaction ComPPI
ARHGEF7 TUBB4A 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ARHGEF7 MCM7 23764002 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
NOD2 ARHGEF7 18684957 27898060 N/A N/A OmniPath
PRKCG ARHGEF7 25009260 27898060 stimulant N/A OmniPath
RAC1 ARHGEF7 14557270 15306850 16492808 18684957 19961560 24792722 27898060 N/A N/A OmniPath
ARHGEF7 RAC1 14557270 15306850 16492808 18684957 19961560 24792722 27898060 9659915 stimulant N/A OmniPath
ARHGEF7 SHC1 18385518 27898060 N/A N/A OmniPath
PAK1 ARHGEF7 10330411 11096073 11157752 16101281 16407834 16492808 16628223 17392278 20936779 23455922 27898060 9659915 9726964 stimulant N/A OmniPath
ARHGEF7 PAK1 10330411 11157752 16101281 16407834 16492808 16628223 17392278 20936779 23455922 27898060 N/A N/A OmniPath
ARHGEF7 CDC42 14505571 15649357 16983070 27898060 9659915 stimulant N/A OmniPath
ARHGEF7 CBLC 14505571 27898060 inhibition N/A OmniPath
ERBIN ARHGEF7 15123239 27898060 N/A N/A OmniPath
ILK ARHGEF7 15513924 27898060 N/A N/A OmniPath
ARHGEF7 ARHGAP1 27898060 9659915 stimulant N/A OmniPath
SHANK1 ARHGEF7 12626503 27898060 stimulant N/A OmniPath
CAMK1 ARHGEF7 18184567 18669648 27898060 N/A N/A OmniPath
ARHGEF7 LRRK2 21048939 27898060 stimulant N/A OmniPath
LRRK2 ARHGEF7 21048939 27898060 stimulant N/A OmniPath

Visualization










  Return