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GENE：CDC42EP3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CDC42EP3
FullNmae CDC42 effector protein 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16943
EnsembleID ENSG00000163171
Uniprot Q9UKI2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CDC42EP3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CDC42EP3 GO:0005515,GO:0005519,GO:0005737,GO:0005829,GO:0005856,GO:0005886,GO:0005886,GO:0007165,GO:0007266,GO:0008360,GO:0012505,GO:0015629,GO:0030838,GO:0031267,GO:0031274

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDC42EP3 YAP1 26192618 26711338 27248291 interaction type N/A ACSN
CDC42 CDC42EP3 10753747 10934474 11248548 11340065 11747822 15001467 15003621 15020669 15169870 15882626 16329184 17517963 17785506 18037882 18719708 19741094 21178402 22126964 22821962 26192618 27248291 7761442 9831565 interaction type N/A ACSN
SRPK1 CDC42EP3 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
CDC42EP3 RHOQ 20005715 interaction type N/A PSP
CDC42EP3 CDC42 20005715 20936779 21071413 9535835 interaction type N/A PSP,SignaLink

Source Target Pmid Interactiontype Methods Database
AR CDC42EP3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CDC42EP3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CDC42EP3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 CDC42EP3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 CDC42EP3 21245298 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 CDC42EP3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 CDC42EP3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CDC42EP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CDC42EP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CDC42EP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CDC42EP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CDC42EP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CDC42EP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CDC42EP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CDC42EP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CDC42EP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CDC42EP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR CDC42EP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CDC42EP3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003380CC CDC42EP3 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS000039E1E1 CDC42EP3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000040780F CDC42EP3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00002FF522 CDC42EP3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00005E6F45 CDC42EP3 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDC42EP3 CDC42 25361965 interaction type N/A PTMCode2
CDC42 CDC42EP3 25361965 interaction type N/A PTMCode2
RHOQ CDC42EP3 25361965 interaction type N/A PTMCode2
CDC42EP3 RHOQ 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC42 CDC42EP3 10490598 14525934 20936779 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,two hybrid ComPPI,HPRD,IntAct
RHOQ CDC42EP3 10490598 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
HNRNPL CDC42EP3 25348397 N/A physical interaction ComPPI
SRPK1 CDC42EP3 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
SNCA CDC42EP3 25348397 N/A physical interaction ComPPI
COPE CDC42EP3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SEPTIN7 CDC42EP3 25348397 N/A physical interaction ComPPI
CDC42EP3 UMPS 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CDC42EP3 SEPTIN6 25348397 N/A physical interaction ComPPI
CDC42EP3 LRRK1 24234451 24947832 25348397 N/A protein array ComPPI,IntAct
CDC42EP3 LRRK2 24234451 24947832 25348397 29513927 N/A protein array ComPPI,IntAct
CDC42EP3 DAPK1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
CDC42EP3 MFHAS1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
CDC42EP3 CDC42EP3 10490598 14525934 16189514 24234451 physical association experimental interaction detection,two hybrid pooling approach,two hybrid HPRD,IntAct
CDC42EP3 MBD2 24234451 27593931 association chromatin immunoprecipitation assay IntAct
SKP1 CDC42EP3 11283612 14581449 27898060 9390558 N/A N/A OmniPath
CEBPZ CDC42EP3 10352012 22139014 27898060 8670864 9390558 N/A N/A OmniPath

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