Gene Information gene info

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GENE：GEM

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GEM
FullNmae GTP binding protein overexpressed in skeletal muscle
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4234
EnsembleID ENSG00000164949
Uniprot P55040

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GEM mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GEM immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GEM autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GEM GO:0000278,GO:0000287,GO:0003924,GO:0005246,GO:0005515,GO:0005516,GO:0005525,GO:0005525,GO:0005634,GO:0005886,GO:0006955,GO:0007165,GO:0007166,GO:0009898,GO:0019003,GO:0030496,GO:0051233,GO:0051276,GO:0051310,GO:0072686

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 GEM 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 GEM 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 GEM 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GEM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GEM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GEM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GEM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GEM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GEM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 GEM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GEM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 GEM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GEM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GEM 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 GEM 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 GEM 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000D0BB4 GEM 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 GEM 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000052EA98 GEM 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004F4657 GEM 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000166778 GEM 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002D349B GEM 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005651EE GEM 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKCZ GEM 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
GEM GOLGA2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM KRTAP10-7 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM KRT31 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM KRT40 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM KCTD9 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM PNMA1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM COG8 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM LZTS2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM GMIP 12093360 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
GEM TRIM23 14525934 16189514 19060904 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
GEM PDLIM7 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
GEM YWHAB 14525934 14701738 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,pull down,in vivo ComPPI,HPRD,IntAct
GEM VTN 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GEM BMP1 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GEM YBEY 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GEM APOH 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GEM RNF7 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GEM CLEC4G 25348397 N/A physical interaction ComPPI
GEM CTSL 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GEM SDHB 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GEM A2M 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GEM NDUFS8 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GEM NDUFAF3 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GEM CLDN15 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GEM TRIM27 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM TCF4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM TRAF1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM BLZF1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM AHCYL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM RUNDC3A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM IKZF3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM TFIP11 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM TRIM54 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM CCDC102B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM SSX2IP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM KLC3 25348397 N/A physical interaction ComPPI
GEM DEUP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM INO80E 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM KRTAP10-3 25348397 N/A physical interaction ComPPI
GEM NOTCH2NLA 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEM HECTD1 25348397 N/A physical interaction ComPPI
GEM SCARB2 25348397 N/A physical interaction ComPPI
GEM CALM1 25348397 N/A physical interaction ComPPI
GEM TFAP4 16924111 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GEM NCOR2 16924111 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GEM HDAC3 16924111 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GEM CACNB1 17052716 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
GEM SPAG5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM ZC4H2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM KRT6A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM PIH1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM ZSCAN9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM MESD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM MCRS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM PLEKHF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM ZNF688 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM CDR2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM BEGAIN 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM USHBP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM TRAF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM MORN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM MIPOL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM MYOG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM VPS52 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM KATNBL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM EXOSC8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM MKRN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM KRT34 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM CYSRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM PRDM14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM BLOC1S2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM ZNF774 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM GADD45GIP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM USH1G 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM PBX4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM ZNF20 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM SORBS3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM KRT83 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM INCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM KRTAP10-8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM LRP2BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM CCDC88B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM MSS51 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM CEP70 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM ZBTB42 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM COG6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM GAS8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM NDUFB7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM PLAGL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM ZRANB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM INSC 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM CCDC125 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM TBC1D3G 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM ASB15 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM HSF2BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM ZNF552 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM PRDM6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM EFHC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM IHO1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM ISCA2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM OIP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM ZMAT5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM VIM 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM ECSIT 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM TRIM32 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM ZNF655 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM TGM7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM GOLGA6L9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM BHLHB9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM CACNB3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPIB GEM 24234451 30021884 physical association cross-linking study IntAct
ATM GEM 14701738 27898060 N/A N/A OmniPath
PRKCZ GEM 14701738 17605761 27898060 N/A N/A OmniPath

Visualization










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