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GENE：IGFBP5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IGFBP5
FullNmae insulin like growth factor binding protein 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5474
EnsembleID ENSG00000115461
Uniprot P24593

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IGFBP5 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IGFBP5 GO:0001558,GO:0001649,GO:0001968,GO:0005515,GO:0005576,GO:0005576,GO:0005615,GO:0005788,GO:0007165,GO:0007565,GO:0014912,GO:0016942,GO:0017148,GO:0030336,GO:0031069,GO:0031994,GO:0031994,GO:0031995,GO:0035556,GO:0042567,GO:0042593,GO:0043567,GO:0043568,GO:0043569,GO:0044342,GO:0045668,GO:0045926,GO:0048009,GO:0048286,GO:0048662,GO:0051146,GO:0051897,GO:0060056,GO:0060416,GO:0071320,GO:0071407,GO:1901862,GO:1904205,GO:1904707,GO:1904754

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR IGFBP5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
GATA2 IGFBP5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 IGFBP5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
RELA IGFBP5 18226221 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2A IGFBP5 7559606 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
TFAP2C IGFBP5 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 IGFBP5 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 IGFBP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA IGFBP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IGFBP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 IGFBP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 IGFBP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 IGFBP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 IGFBP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 IGFBP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETV6 IGFBP5 17242174 trascriptional regulation,stimulation inferred by curator TFlink
MYB IGFBP5 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000821E0 IGFBP5 19948051 25416803 25983620 mrna cleavage,inhibition quantitative reverse transcription pcr,immunohistochemistry TarBase
URS00001597DC IGFBP5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA IGFBP5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000044FD7 IGFBP5 20371350 24039954 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000148B91 IGFBP5 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000011A030 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 IGFBP5 20371350 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000035CC3E IGFBP5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000005481D IGFBP5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE IGFBP5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E IGFBP5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E0524 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000458AD2 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002CAE0C IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005DEC41 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000BF7F9 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000057FDB8 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004F4657 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000006BE7D IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001EE123 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000000C73C IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000521626 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003BBF48 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000023F8DA IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004E008F IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004AAAFF IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001FA076 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000C36BD IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000367985 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000AA464 IGFBP5 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 IGFBP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 IGFBP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F IGFBP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 IGFBP5 23824327 25416803 25990270 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00002E1509 IGFBP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002971AB IGFBP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 IGFBP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018CD09 IGFBP5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003538C1 IGFBP5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D IGFBP5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000017EE98 IGFBP5 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SERPINE1 IGFBP5 25361965 interaction type N/A PTMCode2
IGFBP5 SERPINE1 25361965 interaction type N/A PTMCode2
VTN IGFBP5 25361965 interaction type N/A PTMCode2
IGFBP5 VTN 25361965 interaction type N/A PTMCode2
IGFBP5 THBS1 25361965 interaction type N/A PTMCode2
THBS1 IGFBP5 25361965 interaction type N/A PTMCode2
IGFBP5 SPP1 25361965 interaction type N/A PTMCode2
SPP1 IGFBP5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LMNA IGFBP5 25348397 N/A physical interaction ComPPI
CLDN2 IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLC41A2 IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AQP9 IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BSND IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLC38A1 IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ADAM12 IGFBP5 11095942 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
FHL2 IGFBP5 11821401 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
SPP1 IGFBP5 10698186 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
KPNB1 IGFBP5 10811646 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
F2 IGFBP5 14525934 25348397 27898060 9528953 9883900 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
SERPINE1 IGFBP5 14525934 25348397 27898060 9202242 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
THBS1 IGFBP5 10698186 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
VTN IGFBP5 11751588 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
BAG6 IGFBP5 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SPAG4 IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RASSF1 IGFBP5 14525934 16007340 25348397 27898060 N/A two hybrid,two hybrid ComPPI,HPRD,OmniPath
CREB3 IGFBP5 25348397 N/A two hybrid bait and prey pooling approach ComPPI
FHL1 IGFBP5 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
FBN1 IGFBP5 25348397 N/A pull down ComPPI
APH1A IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GJA8 IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CLDN7 IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CLDN6 IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GJA5 IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PDZK1IP1 IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMIGO1 IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGF2 IGFBP5 14525934 25348397 9497324 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
IGFBP5 PAPPA2 11264294 14525934 25348397 9883900 N/A experimental interaction detection,in vitro ComPPI,HPRD
IGFBP5 PNO1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
IGFBP5 IGF1 15642270 24234451 25348397 N/A isothermal titration calorimetry,physical interaction ComPPI,IntAct
IGFBP5 GJB5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 MFSD5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 MRPS18B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 MS4A3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 ERGIC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 CERS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 TMEM106A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 ABHD4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 THAP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 CXCR1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 KCNK5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 GPR37L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 CD53 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 ASGR1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 MS4A7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 GPX8 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 RHCG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 TMEM179B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 ELOVL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 FNDC9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 SLC10A6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 GPRC5D 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 TMEM52B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 SLC13A4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 TLCD4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 GPR152 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 LDLRAD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 LHFPL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 TSPO2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 CLEC17A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 FAM209A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 PROKR2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 CHODL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 GPR151 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 KIAA2013 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 TMEM106C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 SLC41A3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 GOLM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 FAM20C 24234451 25348397 26091039 phosphorylation reaction protein kinase assay ComPPI,IntAct
LTBP1 IGFBP5 25348397 N/A physical interaction ComPPI
AQP2 IGFBP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FN1 IGFBP5 14525934 14645245 27898060 N/A experimental interaction detection,two hybrid HPRD,OmniPath
TF IGFBP5 11297622 14525934 N/A experimental interaction detection HPRD
IGFALS IGFBP5 14525934 9497324 9786878 N/A experimental interaction detection HPRD
PDIA6 IGFBP5 24234451 30021884 physical association cross-linking study IntAct
CDK5 IGFBP5 17496250 27898060 N/A N/A OmniPath

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