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GENE：MXI1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MXI1
FullNmae MAX interactor 1, dimerization protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7534
EnsembleID ENSG00000119950
Uniprot P50539

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MXI1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MXI1 GO:0000122,GO:0000785,GO:0000977,GO:0000978,GO:0000981,GO:0000981,GO:0001227,GO:0005515,GO:0005634,GO:0005654,GO:0005730,GO:0005829,GO:0006357,GO:0046983,GO:0090575

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP MXI1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
AR MXI1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MXI1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 MXI1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MXI1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MXI1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MXI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MXI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MXI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MXI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MXI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MXI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MXI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MXI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MXI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MXI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MXI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MXI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MXI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYCN MXI1 24403858 trascriptional regulation,stimulation inferred by curator TFlink
E2F2 MXI1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 MXI1 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000237AF9 MXI1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000600E6 MXI1 17242205 22473208 23622248 25416803 mrna cleavage,inhibition array technology,clip,clash TarBase
URS00000F31F4 MXI1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 MXI1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 MXI1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00004E008F MXI1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 MXI1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001B341F MXI1 23254855 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000338542 MXI1 24376632 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000042E1F MXI1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 MXI1 22100165 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C MXI1 22100165 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004407DC MXI1 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 MXI1 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 MXI1 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 MXI1 22100165 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 MXI1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 MXI1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 MXI1 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000272039 MXI1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 MXI1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 MXI1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 MXI1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA MXI1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED MXI1 25416803 26943585 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
MXI1 MAX 25361965 interaction type N/A PTMCode2
MAX MXI1 25361965 interaction type N/A PTMCode2
MXI1 MYC 25361965 interaction type N/A PTMCode2
MYC MXI1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KRTAP10-8 MXI1 25348397 N/A physical interaction ComPPI
KRTAP10-7 MXI1 25348397 N/A physical interaction ComPPI
KRT40 MXI1 25348397 N/A physical interaction ComPPI
BTRC MXI1 25348397 N/A physical interaction ComPPI
SIN3A MXI1 14525934 15467743 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MYC MXI1 14525934 25348397 7565735 N/A two hybrid,two hybrid ComPPI,HPRD
SMARCB1 MXI1 25348397 N/A physical interaction ComPPI
CDC20 MXI1 25348397 N/A physical interaction ComPPI
SMC3 MXI1 14525934 25348397 9528857 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MXI1 SIN3B 14525934 15467743 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MXI1 MAX 14525934 15121849 15809730 16189514 24234451 25348397 25416956 25609649 27705803 association,physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
MXI1 BUB1B 25348397 N/A physical interaction ComPPI
MXI1 APP 25348397 N/A physical interaction ComPPI
MXI1 CALCOCO2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MXI1 KRTAP10-9 25348397 N/A physical interaction ComPPI
MXI1 KRTAP10-3 25348397 N/A physical interaction ComPPI
MXI1 NOTCH2NLA 25348397 N/A physical interaction ComPPI
MXI1 FBXW11 25348397 N/A physical interaction ComPPI
MXI1 MXD3 25348397 N/A physical interaction ComPPI
ENTPD5 MXI1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAX MXI1 10229200 10593926 15121849 15467743 15548375 15809730 16189514 20946988 25416956 25609649 27898060 7954804 9184233 9528857 stimulant N/A OmniPath

Visualization










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