GENE：TGFBI
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TGFBI |
| FullNmae | transforming growth factor beta induced |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:11771 |
| EnsembleID | ENSG00000120708 |
| Uniprot | Q15582 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TGFBI | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TGFBI | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TGFBI | GO:0001525,GO:0002062,GO:0005178,GO:0005201,GO:0005201,GO:0005515,GO:0005518,GO:0005576,GO:0005576,GO:0005604,GO:0005615,GO:0005615,GO:0005802,GO:0005886,GO:0007155,GO:0007162,GO:0007601,GO:0008283,GO:0030198,GO:0031012,GO:0042802,GO:0050839,GO:0050840,GO:0050896,GO:0051179,GO:0051179,GO:0062023,GO:0062023,GO:0070062 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | TGFBI | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | TGFBI | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | TGFBI | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | TGFBI | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | TGFBI | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | TGFBI | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | TGFBI | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TGFBI | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | TGFBI | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TGFBI | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | TGFBI | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TGFBI | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | TGFBI | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | TGFBI | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | TGFBI | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RB1 | TGFBI | 7680889 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SMAD1 | TGFBI | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000009262D | TGFBI | 19136465 | rna interference,inhibition | western blot,miRNA interference luciferase reporter assay | miRSponge |
| URS000009262D | TGFBI | 18591254 19136465 25416803 | mrna cleavage,inhibition | array technology,western blot,miRNA interference luciferase reporter assay | TarBase |
| URS0000065D58 | TGFBI | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS000003ABC4 | TGFBI | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000027464B | TGFBI | 24988946 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS00004F4657 | TGFBI | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EBD4B | TGFBI | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F3336 | TGFBI | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001012BC | TGFBI | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| COL1A2 | TGFBI | 11867580 12034705 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| S100P | TGFBI | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TGFBI | COL4A3 | 11867580 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| TGFBI | COL4A2 | 11867580 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| TGFBI | COL4A1 | 25348397 | N/A | in vitro | ComPPI |
| TGFBI | COL4A4 | 11867580 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| TGFBI | COL2A1 | 14525934 25348397 27898060 9061001 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| TGFBI | COL1A1 | 11867580 12034705 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| TGFBI | A2M | 10681572 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| TGFBI | FBN1 | 25348397 | N/A | pull down | ComPPI |
| TGFBI | FN1 | 11867580 12034705 14525934 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| TGFBI | FAM9B | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |