GENE:ZHX2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ZHX2 |
| FullNmae | zinc fingers and homeoboxes 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:18513 |
| EnsembleID | ENSG00000178764 |
| Uniprot | Q9Y6X8 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ZHX2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ZHX2 | GO:0000122,GO:0000785,GO:0000981,GO:0000981,GO:0003677,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005829,GO:0006357,GO:0006402,GO:0035019,GO:0042802,GO:0042803,GO:0045665,GO:0045892,GO:0046872,GO:0046982,GO:0060040 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | ZHX2 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | ZHX2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | ZHX2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ZHX2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | ZHX2 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | ZHX2 | 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| FOXA1 | ZHX2 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TFAP2C | ZHX2 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | ZHX2 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ZHX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ZHX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ZHX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | ZHX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | ZHX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ZHX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ZHX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | ZHX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | ZHX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | ZHX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MSX1 | ZHX2 | 22078940 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| XBP1 | ZHX2 | 22078940 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HRAS | ZHX2 | 25361965 | interaction type | N/A | PTMCode2 |
| ZHX2 | HRAS | 25361965 | interaction type | N/A | PTMCode2 |
| ZHX2 | NFYA | 25361965 | interaction type | N/A | PTMCode2 |
| NFYA | ZHX2 | 25361965 | interaction type | N/A | PTMCode2 |
| ZHX2 | RAP1A | 25361965 | interaction type | N/A | PTMCode2 |
| RAP1A | ZHX2 | 25361965 | interaction type | N/A | PTMCode2 |
| RAF1 | ZHX2 | 25361965 | interaction type | N/A | PTMCode2 |
| ZHX2 | RAF1 | 25361965 | interaction type | N/A | PTMCode2 |
| RRAS | ZHX2 | 25361965 | interaction type | N/A | PTMCode2 |
| ZHX2 | RRAS | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LAT | ZHX2 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| TP53BP1 | ZHX2 | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| ATXN1 | ZHX2 | 14525934 16713569 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| HRAS | ZHX2 | 25348397 | N/A | physical interaction | ComPPI |
| RRAS | ZHX2 | 25348397 | N/A | physical interaction | ComPPI |
| NFYA | ZHX2 | 12741956 14525934 24234451 25348397 | physical association | anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| YWHAZ | ZHX2 | 25348397 | N/A | physical interaction | ComPPI |
| PARP2 | ZHX2 | 21812934 24234451 25348397 | adp ribosylation reaction | protein array | ComPPI,IntAct |
| HNRNPL | ZHX2 | 25348397 | N/A | physical interaction | ComPPI |
| YWHAQ | ZHX2 | 25348397 | N/A | physical interaction | ComPPI |
| ZHX1 | ZHX2 | 12741956 14525934 24234451 25348397 26496610 | physical association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid | ComPPI,HPRD,IntAct |
| ZHX3 | ZHX2 | 14525934 14659886 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| ZHX2 | APP | 25348397 | N/A | physical interaction | ComPPI |
| ZHX2 | DHRS2 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| ZHX2 | NAGPA | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| ZHX2 | DOCK5 | 25348397 | N/A | physical interaction | ComPPI |
| ABITRAM | ZHX2 | 25348397 | N/A | physical interaction | ComPPI |
| ZHX2 | ZHX2 | 12741956 14525934 24234451 | physical association | two hybrid,experimental interaction detection,pull down,two hybrid | HPRD,IntAct |
| AIFM1 | ZHX2 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| CDC123 | ZHX2 | 10790383 27898060 7823940 9201710 | N/A | N/A | OmniPath |
