Gene Information gene info

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GENE：MOAP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MOAP1
FullNmae modulator of apoptosis 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16658
EnsembleID ENSG00000165943
Uniprot Q96BY2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MOAP1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MOAP1 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MOAP1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MOAP1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
MOAP1 GO:0001844,GO:0005515,GO:0005737,GO:0005739,GO:0005741,GO:0005829,GO:0006914,GO:0008625,GO:0008630,GO:0031625,GO:0042981,GO:0043065,GO:0090200,GO:0097190,GO:0097192,GO:2000786

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MOAP1 EGR1 20690147 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 MOAP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXA1 MOAP1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MOAP1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA MOAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MOAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MOAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MOAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000100748 MOAP1 22434376 rna interference,inhibition western blot,quantitative reverse transcription pcr miRSponge
URS0000100748 MOAP1 22434376 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS00000F31F4 MOAP1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 MOAP1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D MOAP1 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS0000527B00 MOAP1 20371350 22012620 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001A7F58 MOAP1 20371350 22012620 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000B989F MOAP1 20371350 22012620 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 MOAP1 20371350 22012620 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C85B2 MOAP1 20371350 22012620 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003808EC MOAP1 20371350 22012620 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AEA5 MOAP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003758F0 MOAP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001F5B39 MOAP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C7B2B MOAP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000EED18 MOAP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 MOAP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001925C1 MOAP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB35 MOAP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 MOAP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000184017 MOAP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000052EA98 MOAP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000246356 MOAP1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MOAP1 BCL2 25361965 interaction type N/A PTMCode2
BCL2 MOAP1 25361965 interaction type N/A PTMCode2
MOAP1 RASSF1 25361965 interaction type N/A PTMCode2
RASSF1 MOAP1 25361965 interaction type N/A PTMCode2
MOAP1 TRIM39 25361965 interaction type N/A PTMCode2
TRIM39 MOAP1 25361965 interaction type N/A PTMCode2
BAX MOAP1 25361965 interaction type N/A PTMCode2
MOAP1 BAX 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PNMA5 MOAP1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAGEH1 MOAP1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
BCL2L1 MOAP1 11060313 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MOAP1 BAX 11060313 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MOAP1 RASSF1 14525934 15949439 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MOAP1 TNFRSF10A 14525934 15949439 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MOAP1 TNFRSF1A 14525934 15949439 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MOAP1 DPPA2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MOAP1 CCDC85B 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MOAP1 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
MOAP1 BCL2 11060313 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MOAP1 TRIM39 19100260 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MOAP1 CACNA1A 21078624 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MOAP1 RASSF6 25348397 N/A physical interaction ComPPI
MOAP1 FZR1 25348397 N/A physical interaction ComPPI
MOAP1 CAMK2D 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MOAP1 LATS1 25348397 N/A physical interaction ComPPI
MOAP1 THOC1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MOAP1 MBIP 25348397 N/A physical interaction ComPPI
MOAP1 UBR5 25348397 N/A physical interaction ComPPI
MOAP1 DDB1 25348397 N/A physical interaction ComPPI
MOAP1 DYRK2 25348397 N/A physical interaction ComPPI
MOAP1 DCAF1 25348397 N/A physical interaction ComPPI
MOAP1 PNMA1 25348397 N/A physical interaction ComPPI
MOAP1 PNMA8A 25348397 N/A physical interaction ComPPI
MOAP1 MYO5C 25348397 N/A physical interaction ComPPI
MOAP1 SIRT2 25348397 N/A physical interaction ComPPI
MOAP1 PNMA2 25348397 N/A physical interaction ComPPI
MOAP1 ASPM 25348397 N/A physical interaction ComPPI
MOAP1 MYO9B 25348397 N/A physical interaction ComPPI
MOAP1 UBC 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI
MOAP1 UBA52 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI
MOAP1 UBQLN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MOAP1 ZMYND12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MOAP1 PPP2R3C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MOAP1 RUSC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DDIT4L MOAP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBB MOAP1 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI
RPS27A MOAP1 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI
MOAP1 MOAP1 11060313 14525934 N/A experimental interaction detection HPRD
PLEC MOAP1 24234451 30021884 physical association cross-linking study IntAct

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