GENE:FABP4
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | FABP4 |
| FullNmae | fatty acid binding protein 4 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:3559 |
| EnsembleID | ENSG00000170323 |
| Uniprot | P15090 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| FABP4 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| FABP4 | GO:0005324,GO:0005504,GO:0005634,GO:0005634,GO:0005737,GO:0005737,GO:0005811,GO:0005829,GO:0005829,GO:0009617,GO:0015908,GO:0015909,GO:0036041,GO:0042632,GO:0045892,GO:0050729,GO:0050872,GO:0050873,GO:0051427,GO:0070062,GO:0071285,GO:0071356,GO:0120162 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| FABP4 | hsa:2167 | path:hsa03320 | PPAR signaling pathway - Homo sapiens (human) |
| FABP4 | hsa:2167 | path:hsa04923 | Regulation of lipolysis in adipocytes - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | FABP4 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA2 | FABP4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | FABP4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | FABP4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ASXL1 | FABP4 | 21047783 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXO1 | FABP4 | 20102700 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PPARA | FABP4 | 19717768 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PPARG | FABP4 | 11574398 17322100 21047783 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00002A71AD | FABP4 | 21136442 | rna interference,inhibition | experimental interaction detection,miRNA interference luciferase reporter assay | miRSponge |
| URS00002A71AD | FABP4 | 21660946 25416803 | mrna cleavage,inhibition | experimental interaction detection,miRNA interference luciferase reporter assay | TarBase |
| URS0000237AF9 | FABP4 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ZBED1 | FABP4 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| VIM | FABP4 | 14525934 16169070 21900206 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| ACTB | FABP4 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PRKCI | FABP4 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| TNK2 | FABP4 | 25348397 | N/A | physical interaction | ComPPI |
| TFAP2C | FABP4 | 24234451 24835590 25348397 | physical association | two hybrid | ComPPI,IntAct |
| OSTF1 | FABP4 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| INSR | FABP4 | 14525934 1648089 25348397 8463311 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| FABP4 | LIPE | 10318917 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| FABP4 | SNCG | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| FABP4 | EXT2 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| FABP4 | USP15 | 19615732 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| FABP4 | CHD3 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| FABP4 | GDF5 | 25348397 | N/A | physical interaction | ComPPI |
| FABP4 | OAZ3 | 25348397 | N/A | physical interaction | ComPPI |
| ZNF16 | FABP4 | 21874239 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| ACP1 | FABP4 | 1304913 14525934 | N/A | experimental interaction detection | HPRD |
| PLK1 | FABP4 | 1648089 27898060 | N/A | N/A | OmniPath |
| INSR | FABP4 | 1648089 27898060 8463311 | N/A | N/A | OmniPath |
| ACP1 | FABP4 | 1304913 27898060 | N/A | N/A | OmniPath |
