Gene Information gene info

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GENE：EFEMP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EFEMP1
FullNmae EGF containing fibulin extracellular matrix protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3218
EnsembleID ENSG00000115380
Uniprot Q12805

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EFEMP1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EFEMP1 GO:0005006,GO:0005154,GO:0005201,GO:0005509,GO:0005515,GO:0005576,GO:0005576,GO:0005615,GO:0005615,GO:0006355,GO:0007173,GO:0007601,GO:0008083,GO:0018108,GO:0031012,GO:0032331,GO:0043010,GO:0048048,GO:0048050,GO:0062023,GO:0070062

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR EFEMP1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 EFEMP1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA3 EFEMP1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 EFEMP1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA EFEMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EFEMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EFEMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 EFEMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EFEMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 EFEMP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 EFEMP1 N/A trascriptional regulation,stimulation inferred by curator TFlink
TP53 EFEMP1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000254A6 EFEMP1 25416803 28292024 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
TIMP3 EFEMP1 25361965 interaction type N/A PTMCode2
EFEMP1 TIMP3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ZNF408 EFEMP1 25348397 N/A physical interaction ComPPI
NOS3 EFEMP1 21163940 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FAM110A EFEMP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HOXA1 EFEMP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SGTA EFEMP1 16189514 24234451 25348397 25416956 25910212 26871637 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
SLPI EFEMP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MEOX2 EFEMP1 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
ZBTB9 EFEMP1 25348397 N/A physical interaction ComPPI
ZSCAN21 EFEMP1 25348397 N/A physical interaction ComPPI
MKRN3 EFEMP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
POLR3C EFEMP1 25348397 N/A physical interaction ComPPI
TNIP1 EFEMP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ZNF136 EFEMP1 25348397 N/A physical interaction ComPPI
ERRFI1 EFEMP1 25348397 N/A physical interaction ComPPI
OCLN EFEMP1 25348397 N/A physical interaction ComPPI
ARAF EFEMP1 12620389 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KHDRBS1 EFEMP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDIA3 EFEMP1 17170699 24234451 25348397 disulfide bond anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ENO1 EFEMP1 25348397 N/A physical interaction ComPPI
BAG6 EFEMP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
APOD EFEMP1 25348397 N/A physical interaction ComPPI
E4F1 EFEMP1 25348397 N/A physical interaction ComPPI
HSPA5 EFEMP1 25348397 N/A physical interaction ComPPI
ANG EFEMP1 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
TRAF2 EFEMP1 24234451 25348397 25416956 25910212 26871637 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
UBQLN2 EFEMP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GFI1B EFEMP1 16713569 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TIMP3 EFEMP1 15123717 25348397 27898060 N/A two hybrid,in vitro,in vivo ComPPI,OmniPath
CACNA1A EFEMP1 21078624 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RAF1 EFEMP1 12620389 24234451 25348397 physical association two hybrid ComPPI,IntAct
BAG4 EFEMP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AZGP1 EFEMP1 25348397 N/A physical interaction ComPPI
FBLN1 EFEMP1 25348397 N/A physical interaction ComPPI
EFEMP1 RERE 16713569 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EFEMP1 ECM1 25348397 N/A two hybrid ComPPI
EFEMP1 ATXN7 21078624 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EFEMP1 ATN1 16713569 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EFEMP1 SOCS6 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EFEMP1 RIC8A 25348397 N/A physical interaction ComPPI
EFEMP1 TXNDC5 25348397 N/A physical interaction ComPPI
EFEMP1 SHMT2 25348397 N/A physical interaction ComPPI
EFEMP1 MOV10 25348397 N/A physical interaction ComPPI
EFEMP1 NXF1 25348397 N/A physical interaction ComPPI
EFEMP1 ZNF747 25348397 N/A physical interaction ComPPI
EFEMP1 ZNF628 25348397 N/A physical interaction ComPPI
EFEMP1 ZNF398 25348397 N/A physical interaction ComPPI
EFEMP1 ZNF358 25348397 N/A physical interaction ComPPI
EFEMP1 ZNF444 25348397 N/A physical interaction ComPPI
EFEMP1 ZNF316 25348397 N/A physical interaction ComPPI
EFEMP1 ZNF460 25348397 N/A physical interaction ComPPI
EFEMP1 ZNF669 25348397 N/A physical interaction ComPPI
EFEMP1 ZNF324 25348397 N/A physical interaction ComPPI
EFEMP1 ZNF696 25348397 N/A physical interaction ComPPI
EFEMP1 LTBP1 25348397 N/A physical interaction ComPPI
EFEMP1 POLR3G 25348397 N/A physical interaction ComPPI
EFEMP1 BIN2 25348397 N/A physical interaction ComPPI
EFEMP1 ZNF791 25348397 N/A physical interaction ComPPI
EFEMP1 ZNF646 25348397 N/A physical interaction ComPPI
EFEMP1 ZNF768 25348397 N/A physical interaction ComPPI
EFEMP1 EGFL7 25348397 N/A physical interaction ComPPI
EFEMP1 CRTAC1 25348397 N/A physical interaction ComPPI
EFEMP1 TRIM25 25348397 N/A physical interaction ComPPI
EFEMP1 PROP1 23732115 24234451 25348397 physical association two hybrid ComPPI,IntAct
EFEMP1 TFAP2C 24234451 24835590 25348397 physical association two hybrid ComPPI,IntAct
EFEMP1 IGFBP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP1 LCE3D 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP1 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP1 BAG5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP1 CYSRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP1 KRTAP21-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP1 CLPP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP1 KRTAP19-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP1 LCE1C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP1 LCE3A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP1 LCE2C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP1 NR4A3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP1 KRTAP6-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRYBA4 EFEMP1 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
ZNF627 EFEMP1 25348397 N/A physical interaction ComPPI
EFEMP1 EGFR 19804359 27898060 N/A N/A OmniPath

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