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GENE：SPINT2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SPINT2
FullNmae serine peptidase inhibitor, Kunitz type 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11247
EnsembleID ENSG00000167642
Uniprot O43291

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SPINT2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SPINT2 GO:0001843,GO:0004866,GO:0004867,GO:0004867,GO:0005576,GO:0005737,GO:0005886,GO:0007163,GO:0016020,GO:0022408,GO:0060672,GO:0071711,GO:0071773,GO:2000146,GO:2000178

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SPINT2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 SPINT2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SPINT2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SPINT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SPINT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SPINT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SPINT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000039607D SPINT2 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002FAA8C SPINT2 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000032BDF4 SPINT2 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004505E4 SPINT2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000017EA6A SPINT2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RPS7 SPINT2 25348397 N/A physical interaction ComPPI
BAG3 SPINT2 25348397 N/A physical interaction ComPPI
TAF6L SPINT2 25348397 N/A physical interaction ComPPI
CNTNAP1 SPINT2 25348397 N/A physical interaction ComPPI
CTSB SPINT2 14525934 16364318 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
TUBG1 SPINT2 25348397 N/A physical interaction ComPPI
ILK SPINT2 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LEMD3 SPINT2 25348397 N/A physical interaction ComPPI
SREBF2 SPINT2 25348397 N/A physical interaction ComPPI
LRP12 SPINT2 25348397 N/A physical interaction ComPPI
TSC2 SPINT2 25348397 N/A physical interaction ComPPI
ELF2 SPINT2 25348397 N/A physical interaction ComPPI
ARFGEF1 SPINT2 25348397 N/A physical interaction ComPPI
CDC20 SPINT2 25348397 N/A physical interaction ComPPI
ACVR1B SPINT2 25348397 N/A physical interaction ComPPI
OCRL SPINT2 25348397 N/A physical interaction ComPPI
CUL7 SPINT2 25348397 N/A physical interaction ComPPI
VANGL2 SPINT2 25348397 N/A physical interaction ComPPI
PKMYT1 SPINT2 25348397 N/A physical interaction ComPPI
PI4K2B SPINT2 25348397 N/A physical interaction ComPPI
DIP2A SPINT2 25348397 N/A physical interaction ComPPI
CKAP5 SPINT2 25348397 N/A physical interaction ComPPI
IQCB1 SPINT2 25348397 N/A physical interaction ComPPI
DPH1 SPINT2 25348397 N/A physical interaction ComPPI
SPINT2 ITIH3 14525934 25348397 27898060 9359851 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
SPINT2 ITIH2 25348397 N/A physical interaction ComPPI
SPINT2 APP 25348397 N/A physical interaction ComPPI
SPINT2 MOV10 25348397 N/A physical interaction ComPPI
SPINT2 TUBGCP2 25348397 N/A physical interaction ComPPI
SPINT2 FNDC3A 25348397 N/A physical interaction ComPPI
SPINT2 TBL2 25348397 N/A physical interaction ComPPI
SPINT2 SACM1L 25348397 N/A physical interaction ComPPI
SPINT2 ZDHHC13 25348397 N/A physical interaction ComPPI
SPINT2 DHRS7 25348397 N/A physical interaction ComPPI
SPINT2 CYP51A1 25348397 N/A physical interaction ComPPI
SPINT2 PRR14 25348397 N/A physical interaction ComPPI
SPINT2 SMC2 25348397 N/A physical interaction ComPPI
SPINT2 EPHX1 25348397 N/A physical interaction ComPPI
SPINT2 POLE2 25348397 N/A physical interaction ComPPI
SPINT2 HMGCR 25348397 N/A physical interaction ComPPI
SPINT2 VRK2 25348397 N/A physical interaction ComPPI
SPINT2 SLC39A10 25348397 N/A physical interaction ComPPI
SPINT2 FAM189B 25348397 N/A physical interaction ComPPI
SPINT2 CHD8 25348397 N/A physical interaction ComPPI
SPINT2 SLC27A3 25348397 N/A physical interaction ComPPI
SPINT2 KLHL26 25348397 N/A physical interaction ComPPI
SPINT2 ASPHD2 25348397 N/A physical interaction ComPPI
SPINT2 GPN3 25348397 N/A physical interaction ComPPI
THAP11 SPINT2 25348397 N/A physical interaction ComPPI

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