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GENE：IGFBP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IGFBP2
FullNmae insulin like growth factor binding protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5471
EnsembleID ENSG00000115457
Uniprot P18065

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IGFBP2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IGFBP2 GO:0005102,GO:0005515,GO:0005576,GO:0005576,GO:0005615,GO:0005615,GO:0007565,GO:0007584,GO:0009410,GO:0009612,GO:0016324,GO:0031994,GO:0031994,GO:0031995,GO:0031995,GO:0032355,GO:0032526,GO:0032870,GO:0042104,GO:0043567,GO:0043567,GO:0043567,GO:0043627,GO:0051384,GO:0070062,GO:0090090

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CTNNB1 IGFBP2 15735679 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 IGFBP2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
NEUROD1 IGFBP2 19679880 trascriptional regulation,stimulation chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
YBX1 IGFBP2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 IGFBP2 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA IGFBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IGFBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 IGFBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 IGFBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS IGFBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 IGFBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A IGFBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 IGFBP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
JUN IGFBP2 N/A trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 IGFBP2 N/A trascriptional regulation,stimulation inferred by curator TFlink
SP1 IGFBP2 N/A trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A IGFBP2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001D69F6 IGFBP2 22170610 rna interference,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS00001D69F6 IGFBP2 22170610 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 IGFBP2 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000029D9F1 IGFBP2 25416803 27487563 mrna cleavage,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001919B0 IGFBP2 24747968 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000812128 IGFBP2 24297251 direct interaction,inhibition high throughput sequencing StarBase

Source Target Pmid Interactiontype Methods Database
INO80B IGFBP2 19095771 24234451 25348397 27898060 colocalization,physical association anti bait coimmunoprecipitation,two hybrid,pull down,physical interaction,confocal microscopy ComPPI,IntAct,OmniPath
EGFR IGFBP2 25348397 N/A physical interaction ComPPI
IGF2 IGFBP2 14525934 1714916 2465304 25348397 8781553 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
DEFA1 IGFBP2 25348397 N/A physical interaction ComPPI
IGFBP2 IGF1 25348397 N/A physical interaction ComPPI
IGFBP2 GSDMB 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KLK2 IGFBP2 11358513 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath
TF IGFBP2 11297622 14525934 N/A experimental interaction detection HPRD

Visualization










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