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GENE：NR2C2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NR2C2
FullNmae nuclear receptor subfamily 2 group C member 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7972
EnsembleID ENSG00000177463
Uniprot P49116

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NR2C2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NR2C2 GO:0000122,GO:0000785,GO:0000977,GO:0000978,GO:0000978,GO:0000981,GO:0001228,GO:0003700,GO:0004879,GO:0005515,GO:0005654,GO:0005654,GO:0006355,GO:0007283,GO:0007399,GO:0008270,GO:0030154,GO:0030522,GO:0040019,GO:0043565,GO:0045944,GO:0045944,GO:0048856,GO:1990837

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IFIT5 NR2C2 23180781 26334375 physical association anti tag coimmunoprecipitation InnateDB
NR2C2 HNF4A 12522137 23331499 stimulation N/A SignaLink
NR2C2 AR 10611280 23331499 stimulation N/A SignaLink
NR2C2 ESR1 10611280 11844790 23331499 stimulation N/A SignaLink
NR2C2 ESR2 11844790 23331499 stimulation N/A SignaLink
NRIP1 NR2C2 16887930 23331499 inhibition N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR NR2C2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NR2C2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 NR2C2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NR2C2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NR2C2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NR2C2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 NR2C2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
DR1 NR2C2 21126370 trascriptional regulation,stimulation inferred by curator TFlink
ELK4 NR2C2 21126370 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 NR2C2 15764709 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D NR2C2 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 NR2C2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000003ABC4 NR2C2 24565101 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000008A99 NR2C2 24105952 25416803 28194669 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000042E1F NR2C2 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 NR2C2 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5659 NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001D6605 NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002F5FEE NR2C2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001D69F6 NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000000E601 NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 NR2C2 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 NR2C2 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA NR2C2 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 NR2C2 20371350 21572407 22473208 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000016D2D4 NR2C2 20371350 21572407 23446348 25416803 26821827 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS00004AC389 NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C NR2C2 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 NR2C2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB NR2C2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 NR2C2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 NR2C2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075ABF4 NR2C2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB NR2C2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 NR2C2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 NR2C2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 NR2C2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D NR2C2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C NR2C2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 NR2C2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB NR2C2 25416803 26617776 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
NR2C2 NRIP1 25361965 interaction type N/A PTMCode2
NRIP1 NR2C2 25361965 interaction type N/A PTMCode2
NR2C2 NR2C1 25361965 interaction type N/A PTMCode2
NR2C1 NR2C2 25361965 interaction type N/A PTMCode2
NR2C2 AR 25361965 interaction type N/A PTMCode2
AR NR2C2 25361965 interaction type N/A PTMCode2
HNF4A NR2C2 25361965 interaction type N/A PTMCode2
NR2C2 HNF4A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNW1 NR2C2 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
S100A4 NR2C2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMARCC1 NR2C2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP1 NR2C2 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
TRAF6 NR2C2 25348397 N/A physical interaction ComPPI
HSP90AB1 NR2C2 14525934 14743216 22939624 24234451 25348397 physical association experimental interaction detection,in vitro,luminescence based mammalian interactome mapping ComPPI,HPRD,IntAct
AIM2 NR2C2 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
CBLB NR2C2 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
CD2AP NR2C2 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
AR NR2C2 10611280 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
HDAC3 NR2C2 25348397 N/A physical interaction ComPPI
HDAC4 NR2C2 25348397 N/A physical interaction ComPPI
UBB NR2C2 25348397 N/A physical interaction ComPPI
HSP90AA1 NR2C2 14525934 14743216 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PRPF40A NR2C2 25348397 N/A physical interaction ComPPI
IKBKB NR2C2 12547194 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PEBP1 NR2C2 11585904 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PDLIM7 NR2C2 25348397 N/A physical interaction ComPPI
RBBP4 NR2C2 25348397 N/A physical interaction ComPPI
TRAF2 NR2C2 12547194 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
RXRB NR2C2 14525934 15604093 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
CUL4B NR2C2 25348397 N/A physical interaction ComPPI
CD70 NR2C2 25348397 N/A physical interaction ComPPI
TRIM28 NR2C2 25348397 N/A physical interaction ComPPI
MTA1 NR2C2 25348397 N/A physical interaction ComPPI
CHUK NR2C2 12547194 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
HNF4A NR2C2 12522137 25348397 27898060 N/A physical interaction,in vitro,in vivo ComPPI,OmniPath
EED NR2C2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAB2 NR2C2 14525934 14633987 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PELI2 NR2C2 25348397 N/A physical interaction ComPPI
NR2C2 NR2C1 12093744 14525934 21670149 25348397 27898060 9737983 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
NR2C2 NR2C2AP 12486131 14525934 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,fluorescence microscopy,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
NR2C2 CDC37 14525934 14743216 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
NR2C2 JAZF1 14525934 15302918 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,confocal microscopy,gal4 vp16 complementation,two hybrid ComPPI,HPRD,IntAct
NR2C2 ESR1 11844790 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
NR2C2 ITSN2 25348397 N/A physical interaction ComPPI
NR2C2 DNMT1 25348397 N/A physical interaction ComPPI
NR2C2 HDAC1 25348397 N/A physical interaction ComPPI
NR2C2 CHD4 25348397 N/A physical interaction ComPPI
NR2C2 KDM1A 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NR2C2 TAB1 14525934 14743216 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
NR2C2 RBCK1 25348397 N/A physical interaction ComPPI
NR2C2 HSP90AA2P 25348397 N/A physical interaction ComPPI
NR2C2 DDB1 25348397 N/A physical interaction ComPPI
NR2C2 DCAF1 25348397 N/A physical interaction ComPPI
NR2C2 AFDN 25348397 N/A physical interaction ComPPI
NR2C2 RPP38 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NR2C2 PATZ1 25348397 N/A physical interaction ComPPI
NR2C2 TANC2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NR2C2 RBMX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NR2C2 KLHL7 25348397 N/A physical interaction ComPPI
NR2C2 FOXL1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NR2C2 TRIM25 25348397 N/A physical interaction ComPPI
NR2C2 PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
PELI1 NR2C2 25348397 N/A physical interaction ComPPI
NR2C2 FKBP5 14525934 14743216 N/A experimental interaction detection HPRD
MKI67 NR2C2 24234451 26949251 association anti tag coimmunoprecipitation IntAct
SMAD6 NR2C2 11737269 27898060 inhibition N/A OmniPath
PRKAA1 NR2C2 21478464 27898060 inhibition N/A OmniPath
JAZF1 NR2C2 15302918 27898060 inhibition N/A OmniPath

Visualization










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