GENE:CCN1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CCN1 |
| FullNmae | cellular communication network factor 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:2654 |
| EnsembleID | ENSG00000142871 |
| Uniprot | O00622 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CCN1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CCN1 | GO:0001649,GO:0001934,GO:0002041,GO:0003181,GO:0003278,GO:0003281,GO:0005178,GO:0005201,GO:0005515,GO:0005576,GO:0005788,GO:0006935,GO:0007165,GO:0008201,GO:0010811,GO:0019838,GO:0030198,GO:0030335,GO:0030501,GO:0030513,GO:0033690,GO:0043065,GO:0043066,GO:0044319,GO:0045669,GO:0045860,GO:0045944,GO:0050840,GO:0060413,GO:0060591,GO:0060710,GO:0060716,GO:0061036,GO:0062023,GO:0070372,GO:0072593,GO:2000304 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | CCN1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | CCN1 | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| YBX1 | CCN1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| RELA | CCN1 | 20018891 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CCN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CCN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CCN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CCN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | CCN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CCN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | CCN1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GLI1 | CCN1 | 22056874 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| STAT3 | CCN1 | 22401280 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CREB1 | CCN1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | CCN1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000338542 | CCN1 | 20452491 | rna interference,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
| URS0000016914 | CCN1 | 23056551 | rna interference,inhibition | western blot | miRSponge |
| URS0000065D58 | CCN1 | N/A 16239240 | rna interference,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
| URS0000065D58 | CCN1 | 16239240 25416803 | mrna cleavage,inhibition | western blot,western blot,quantitative reverse transcription pcr,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS0000338542 | CCN1 | 18668040 20452491 24705102 25416803 | mrna cleavage,inhibition | array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS0000016914 | CCN1 | 23056551 25416803 | mrna cleavage,inhibition | western blot | TarBase |
| URS000003ABC4 | CCN1 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000096022 | CCN1 | 24449575 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS00001A405B | CCN1 | 24317814 25416803 | mrna cleavage,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS000032FC1A | CCN1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | CCN1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000070CD2 | CCN1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000076995 | CCN1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003B59DF | CCN1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000472A9B | CCN1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001E0AEA | CCN1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | CCN1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000260A3A | CCN1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ITGB5 | CCN1 | 11287419 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| ITGAV | CCN1 | 10821835 11287419 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| APOD | CCN1 | 25348397 | N/A | physical interaction | ComPPI |
| MYC | CCN1 | 17314511 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| UBQLN2 | CCN1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| SOX2 | CCN1 | 25348397 | N/A | physical interaction | ComPPI |
| SFN | CCN1 | 25348397 | N/A | physical interaction | ComPPI |
| CCN1 | ZWINT | 20360068 24234451 25348397 | physical association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| CCN1 | CUL7 | 25348397 | N/A | physical interaction | ComPPI |
| CCN1 | CNTROB | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CCN1 | BCAR1 | 24234451 25348397 28007913 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
