GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
DFFB |
FullNmae |
DNA fragmentation factor subunit beta |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:2773 |
EnsembleID |
ENSG00000169598 |
Uniprot |
O76075 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
DFFB |
necroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
DFFB |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
DFFB |
autosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
DFFB |
apoptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
DFFB |
GO:0000785,GO:0003677,GO:0004520,GO:0004536,GO:0004536,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005730,GO:0005829,GO:0005829,GO:0006308,GO:0006309,GO:0006309,GO:0019899,GO:0019904,GO:0030263,GO:0032991,GO:0042802,GO:0097718,GO:1902511 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
APP |
DFFB |
21832049
23180781
|
physical association |
protein array |
InnateDB |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
CIDEB |
DFFB |
20005715
|
interaction type |
N/A |
PSP |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
ETS1 |
DFFB |
20019798
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
CTCF |
DFFB |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
DFFB |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
DFFB |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TRIM28 |
DFFB |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TAL1 |
DFFB |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HDAC2 |
DFFB |
14559996
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
MYC |
DFFB |
10931841
17706770
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
SMARCA4 |
DFFB |
14559996
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
ESR1 |
DFFB |
N/A
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
USF1 |
DFFB |
N/A
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
USF2 |
DFFB |
N/A
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00004505E4 |
DFFB |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
URS0000355E82 |
DFFB |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000458AD2 |
DFFB |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000006372A |
DFFB |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000057FDB8 |
DFFB |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00004214BB |
DFFB |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00003FBC84 |
DFFB |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000075B0F6 |
DFFB |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000211070 |
DFFB |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00005586D0 |
DFFB |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000486E0B |
DFFB |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000021202F |
DFFB |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00005CCD18 |
DFFB |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000075CC78 |
DFFB |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000075D814 |
DFFB |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001012BC |
DFFB |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00003AD2AA |
DFFB |
25416803
27292025
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
CUL5 |
DFFB |
25348397
|
N/A |
physical interaction |
ComPPI |
BMI1 |
DFFB |
20601937
24234451
25348397
|
association |
tandem affinity purification |
ComPPI,IntAct |
PRKACB |
DFFB |
25348397
|
N/A |
physical interaction |
ComPPI |
COPS5 |
DFFB |
25348397
|
N/A |
physical interaction |
ComPPI |
PKN2 |
DFFB |
25348397
|
N/A |
physical interaction |
ComPPI |
UBB |
DFFB |
25348397
|
N/A |
physical interaction |
ComPPI |
PARP2 |
DFFB |
21812934
24234451
25348397
|
adp ribosylation reaction |
protein array |
ComPPI,IntAct |
HNRNPL |
DFFB |
25348397
|
N/A |
physical interaction |
ComPPI |
MARCKS |
DFFB |
25348397
|
N/A |
physical interaction |
ComPPI |
NEDD8 |
DFFB |
25348397
|
N/A |
physical interaction |
ComPPI |
CUL2 |
DFFB |
25348397
|
N/A |
physical interaction |
ComPPI |
CUL1 |
DFFB |
25348397
|
N/A |
physical interaction |
ComPPI |
H1-5 |
DFFB |
19882353
24234451
25348397
|
association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
PTPN13 |
DFFB |
25348397
|
N/A |
physical interaction |
ComPPI |
CAND1 |
DFFB |
25348397
|
N/A |
physical interaction |
ComPPI |
NUBP1 |
DFFB |
25348397
|
N/A |
physical interaction |
ComPPI |
DFFA |
DFFB |
10409614
10527860
10527861
10932250
11371636
14525934
17353931
19882353
24234451
25348397
9108473
9422506
|
physical association |
anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,filter binding,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach |
ComPPI,HPRD,IntAct |
DFFB |
CIDEB |
10619428
14525934
25348397
|
N/A |
experimental interaction detection,physical interaction,in vitro,in vivo |
ComPPI,HPRD |
DFFB |
TOP2A |
10959840
14525934
25348397
27898060
|
N/A |
experimental interaction detection,physical interaction,in vitro |
ComPPI,HPRD,OmniPath |
DFFB |
LTB4R2 |
25348397
|
N/A |
physical interaction |
ComPPI |
DFFB |
APP |
25348397
|
N/A |
physical interaction |
ComPPI |
DFFB |
MAGOH |
25348397
|
N/A |
physical interaction |
ComPPI |
DFFB |
LRRC15 |
25348397
|
N/A |
physical interaction |
ComPPI |
DFFB |
NEFH |
25348397
|
N/A |
physical interaction |
ComPPI |
DFFB |
H1-1 |
19882353
24234451
25348397
|
association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
DFFB |
H1-0 |
19882353
24234451
25348397
|
association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
DFFB |
H1-3 |
19882353
24234451
25348397
|
association |
anti bait coimmunoprecipitation |
ComPPI,IntAct |
DFFB |
LRRK2 |
24234451
24947832
25348397
|
N/A |
protein array |
ComPPI,IntAct |
DFFB |
DFFB |
14525934
15149602
|
N/A |
experimental interaction detection |
HPRD |
VIM |
DFFB |
24234451
30021884
|
physical association |
cross-linking study |
IntAct |
DFFA |
DFFB |
10409614
10527860
10527861
10932250
11371636
12655299
15572351
17353931
19882353
26186194
27898060
9108473
9422506
9422513
|
inhibition |
N/A |
OmniPath |
CASP3 |
DFFB |
27898060
9108473
|
stimulant |
N/A |
OmniPath |
Visualization