Gene Information gene info

GENE:PSMD12

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSMD12
FullNmae proteasome 26S subunit, non-ATPase 12
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9557
EnsembleID ENSG00000197170
Uniprot O00232

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSMD12 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMD12 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMD12 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMD12 apoptosis 37037907 PSMD12 knockdown promoted cell apoptosis. retulator signature

Go Annotation:

GeneSymbol Go id
PSMD12 GO:0000502,GO:0000502,GO:0005515,GO:0005576,GO:0005654,GO:0005737,GO:0005829,GO:0005838,GO:0008541,GO:0016020,GO:0022624,GO:0034774,GO:0043161,GO:0070062,GO:1904813

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSMD12 hsa:5718 path:hsa03050 Proteasome - Homo sapiens (human)
PSMD12 hsa:5718 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PSMD12 hsa:5718 path:hsa05012 Parkinson disease - Homo sapiens (human)
PSMD12 hsa:5718 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PSMD12 hsa:5718 path:hsa05016 Huntington disease - Homo sapiens (human)
PSMD12 hsa:5718 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
PSMD12 hsa:5718 path:hsa05020 Prion disease - Homo sapiens (human)
PSMD12 hsa:5718 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
PSMD12 hsa:5718 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TRAF6 PSMD12 14743216 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR PSMD12 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 PSMD12 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 PSMD12 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PSMD12 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PSMD12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PSMD12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PSMD12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PSMD12 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001E0AEA PSMD12 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS0000028BB8 PSMD12 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00004977C5 PSMD12 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 PSMD12 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SNW1 PSMD12 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L PSMD12 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
USP20 PSMD12 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3H PSMD12 25348397 N/A physical interaction ComPPI
SGTA PSMD12 25348397 N/A physical interaction ComPPI
BAG3 PSMD12 25348397 N/A physical interaction ComPPI
NPM1 PSMD12 25348397 N/A physical interaction ComPPI
PSMC3 PSMD12 25348397 N/A physical interaction ComPPI
PSMC6 PSMD12 20890303 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD14 PSMD12 19615732 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRAF6 PSMD12 14525934 14743216 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
PSMD7 PSMD12 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CALM1 PSMD12 25348397 N/A physical interaction ComPPI
PSMB2 PSMD12 25348397 N/A physical interaction ComPPI
EIF3E PSMD12 20890303 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
INSIG2 PSMD12 25348397 N/A physical interaction ComPPI
ABRAXAS2 PSMD12 19214193 24234451 25348397 association biochemical ComPPI,IntAct
JUN PSMD12 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
FLNC PSMD12 25348397 N/A physical interaction ComPPI
PSMA3 PSMD12 25348397 N/A physical interaction ComPPI
PSMD11 PSMD12 25348397 N/A physical interaction ComPPI
ITGAV PSMD12 25348397 N/A physical interaction ComPPI
UBC PSMD12 25348397 N/A physical interaction ComPPI
PSMA1 PSMD12 25348397 N/A physical interaction ComPPI
PSMA6 PSMD12 25348397 N/A physical interaction ComPPI
PSMA5 PSMD12 25348397 N/A physical interaction ComPPI
PSMB9 PSMD12 25348397 N/A physical interaction ComPPI
HDLBP PSMD12 25348397 N/A physical interaction ComPPI
HMGB2 PSMD12 25348397 N/A physical interaction ComPPI
CAD PSMD12 25348397 N/A physical interaction ComPPI
CFTR PSMD12 25348397 N/A physical interaction ComPPI
MAPK6 PSMD12 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
PSMD8 PSMD12 25348397 N/A physical interaction ComPPI
SQSTM1 PSMD12 25348397 N/A physical interaction ComPPI
PSMB8 PSMD12 25348397 N/A physical interaction ComPPI
PSMD1 PSMD12 25348397 N/A physical interaction ComPPI
EIF3C PSMD12 25348397 N/A physical interaction ComPPI
PSMC5 PSMD12 25348397 N/A physical interaction ComPPI
HUWE1 PSMD12 25348397 N/A physical interaction ComPPI
RAD23A PSMD12 25348397 N/A physical interaction ComPPI
CUL1 PSMD12 25348397 N/A physical interaction ComPPI
PSMC4 PSMD12 25348397 N/A physical interaction ComPPI
RNF2 PSMD12 25348397 N/A physical interaction ComPPI
NOS2 PSMD12 25348397 N/A physical interaction ComPPI
COPS7A PSMD12 25348397 N/A physical interaction ComPPI
PSMD2 PSMD12 25348397 N/A physical interaction ComPPI
VCAM1 PSMD12 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
FLNB PSMD12 25348397 N/A physical interaction ComPPI
RAD23B PSMD12 20890303 24234451 25348397 physical association pull down ComPPI,IntAct
PRKN PSMD12 25348397 N/A physical interaction ComPPI
PSMD10 PSMD12 17353931 19490896 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD4 PSMD12 16990800 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FKBP8 PSMD12 25348397 N/A physical interaction ComPPI
SEM1 PSMD12 25348397 N/A physical interaction ComPPI
PSMB5 PSMD12 25348397 N/A physical interaction ComPPI
PSME3 PSMD12 25348397 N/A physical interaction ComPPI
PSME1 PSMD12 25348397 N/A physical interaction ComPPI
ELP1 PSMD12 25348397 N/A physical interaction ComPPI
COPE PSMD12 25348397 N/A physical interaction ComPPI
PSMC1 PSMD12 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ESR2 PSMD12 21182203 24234451 25348397 association cosedimentation through density gradient ComPPI,IntAct
BRCA1 PSMD12 25348397 N/A physical interaction ComPPI
MCFD2 PSMD12 25348397 N/A physical interaction ComPPI
PSMB4 PSMD12 25348397 N/A physical interaction ComPPI
EIF3D PSMD12 20890303 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB1 PSMD12 25348397 N/A physical interaction ComPPI
PSMB3 PSMD12 25348397 N/A physical interaction ComPPI
PSMB7 PSMD12 25348397 N/A physical interaction ComPPI
PSMA7 PSMD12 25348397 N/A physical interaction ComPPI
PSMA4 PSMD12 25348397 N/A physical interaction ComPPI
EIF3L PSMD12 25348397 N/A physical interaction ComPPI
RNF11 PSMD12 25348397 N/A physical interaction ComPPI
PSMD5 PSMD12 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IKBKE PSMD12 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TRIM11 PSMD12 25348397 N/A physical interaction ComPPI
PPID PSMD12 25348397 N/A physical interaction ComPPI
CAT PSMD12 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
UGGT1 PSMD12 25348397 N/A physical interaction ComPPI
EIF3M PSMD12 25348397 N/A physical interaction ComPPI
UCHL5 PSMD12 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPA0 PSMD12 25348397 N/A physical interaction ComPPI
MCM7 PSMD12 25348397 N/A physical interaction ComPPI
NAA16 PSMD12 25348397 N/A physical interaction ComPPI
FUS PSMD12 25348397 N/A physical interaction ComPPI
HSD17B10 PSMD12 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NME2 PSMD12 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ADRM1 PSMD12 24234451 24811749 25348397 association physical interaction,blue native page ComPPI,IntAct
PSMD13 PSMD12 14525934 16501559 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
PSMD12 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD12 PAAF1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD12 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD12 RNF185 25348397 N/A physical interaction ComPPI
PSMD12 SEM1 25348397 N/A physical interaction ComPPI
PSMD12 PCK1 25348397 N/A physical interaction ComPPI
PSMD12 PSMD3 25348397 N/A physical interaction ComPPI
PSMD12 SIRT7 25348397 N/A physical interaction ComPPI
PSMD12 PSMA2 25348397 N/A physical interaction ComPPI
PSMD12 PSMC2 25348397 N/A physical interaction ComPPI
PSMD12 PSMB6 25348397 N/A physical interaction ComPPI
PSMD12 KCMF1 25348397 N/A physical interaction ComPPI
PSMD12 TXNL1 25348397 N/A physical interaction ComPPI
PSMD12 CCDC74B 25348397 N/A physical interaction ComPPI
PSMD12 CCDC92 25348397 N/A physical interaction ComPPI
PSMD12 AMBRA1 25348397 N/A physical interaction ComPPI
PSMD12 NAA15 25348397 N/A physical interaction ComPPI
PSMD12 AHCYL1 25348397 N/A physical interaction ComPPI
PSMD12 NLRP9 25348397 N/A physical interaction ComPPI
PSMD12 PSMD9 25348397 N/A physical interaction ComPPI
PSMD12 ENPP1 25348397 N/A physical interaction ComPPI
PSMD12 STKLD1 25348397 N/A physical interaction ComPPI
PSMD12 KDELR1 25348397 N/A physical interaction ComPPI
PSMD12 INTU 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PSMD12 CCND2 25348397 N/A physical interaction ComPPI
PSMD12 FTSJ1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
UBLCP1 PSMD12 25348397 N/A physical interaction ComPPI
GH1 PSMD12 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ECPAS PSMD12 25348397 N/A physical interaction ComPPI
DNAJC5 PSMD12 24234451 29997244 physical association bioluminescence resonance energy transfer IntAct
PSMD12 TRAF6 14743216 17353931 27898060 N/A N/A OmniPath

Visualization