Gene Information gene info

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GENE：HPGD

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HPGD
FullNmae 15-hydroxyprostaglandin dehydrogenase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5154
EnsembleID ENSG00000164120
Uniprot P15428

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HPGD autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HPGD GO:0001822,GO:0004957,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0005829,GO:0006693,GO:0006693,GO:0007179,GO:0007565,GO:0007565,GO:0007567,GO:0016323,GO:0016404,GO:0016404,GO:0016404,GO:0016404,GO:0016616,GO:0019372,GO:0030728,GO:0032355,GO:0032496,GO:0042802,GO:0043065,GO:0045471,GO:0045786,GO:0051287,GO:0070062,GO:0070403,GO:0070493,GO:0097070,GO:1904707,GO:1905828

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HPGD hsa:3248 path:hsa00590 Arachidonic acid metabolism - Homo sapiens (human)
HPGD hsa:3248 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA1 HPGD 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 HPGD 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 HPGD 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 HPGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 HPGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HPGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HPGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HPGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HPGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HPGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 HPGD 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CREB1 HPGD 10650939 trascriptional regulation,stimulation inferred by curator TFlink
ERG HPGD 21178489 trascriptional regulation,stimulation inferred by curator TFlink
KCNH2 HPGD 21178489 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 HPGD 10650939 trascriptional regulation,stimulation inferred by curator TFlink
NFIL3 HPGD 1620116 trascriptional regulation,stimulation inferred by curator TFlink
SNAI2 HPGD 17575121 trascriptional regulation,stimulation inferred by curator TFlink
ATF4 HPGD N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F4 HPGD N/A trascriptional regulation,stimulation inferred by curator TFlink
ETV4 HPGD N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D HPGD 24699315 25416803 27561985 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000C48FA HPGD 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000259AE4 HPGD 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
APP HPGD 25348397 N/A physical interaction ComPPI

Visualization










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