Gene Information gene info

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GENE：GMNN

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GMNN
FullNmae geminin DNA replication inhibitor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17493
EnsembleID ENSG00000112312
Uniprot O75496

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GMNN mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GMNN immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GMNN autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GMNN GO:0003682,GO:0003714,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0006275,GO:0007346,GO:0008156,GO:0008156,GO:0009887,GO:0017053,GO:0017053,GO:0030174,GO:0035563,GO:0042826,GO:0045786,GO:0045786,GO:0045786,GO:0045892,GO:0071163,GO:0140297,GO:2000104

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR GMNN 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 GMNN 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 GMNN 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 GMNN 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GMNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GMNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GMNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GMNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GMNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GMNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GMNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GMNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GMNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 GMNN 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001F5B39 GMNN 21418558 rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS00003758F0 GMNN 21418558 rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS00001F5B39 GMNN 21418558 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS00003758F0 GMNN 21418558 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS00000AA464 GMNN 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 GMNN 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000005481D GMNN 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000028BB8 GMNN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001AFC71 GMNN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 GMNN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004505E4 GMNN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A281 GMNN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000023133F GMNN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001A4ABF GMNN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000002569A GMNN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002E1509 GMNN 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000023F8DA GMNN 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 GMNN 22135298 phosphorylation N/A PhosphoSite
AURKA GMNN 22135298 phosphorylation N/A PhosphoSite
GMNN CDKN1A 25361965 interaction type N/A PTMCode2
CDKN1A GMNN 25361965 interaction type N/A PTMCode2
GMNN SIX3 25361965 interaction type N/A PTMCode2
SIX3 GMNN 25361965 interaction type N/A PTMCode2
GMNN MCM6 25361965 interaction type N/A PTMCode2
MCM6 GMNN 25361965 interaction type N/A PTMCode2
GMNN SCMH1 25361965 interaction type N/A PTMCode2
SCMH1 GMNN 25361965 interaction type N/A PTMCode2
GMNN SUMO1 25361965 interaction type N/A PTMCode2
SUMO1 GMNN 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CKS1B GMNN 25348397 N/A physical interaction ComPPI
HSPA8 GMNN 25348397 N/A physical interaction ComPPI
GMNN MCM6 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
GMNN CDT1 11125146 14525934 14993212 15232106 16482215 17318181 19906994 21543332 22581055 24234451 25348397 26496610 27107012 association,physical association anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,fluorescent resonance energy transfer,molecular sieving,peptide array,protein array,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,in vitro,in vivo,x ray scattering,surface plasmon resonance array,validated two hybrid,barcode fusion genetics two hybrid ComPPI,HPRD,IntAct
GMNN SCMH1 25348397 N/A in vitro ComPPI
GMNN PHC1 14525934 14973489 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GMNN CDKN1A 14525934 15232106 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction,in vitro ComPPI,HPRD,IntAct
GMNN CDKN2A 15232106 24234451 25348397 N/A protein array,physical interaction,in vitro ComPPI,IntAct
GMNN SIX3 14525934 14973488 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
GMNN NCF1 25348397 N/A two hybrid,physical interaction ComPPI
GMNN HOXA7 14525934 14973489 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GMNN HOXA10 14525934 14973489 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GMNN HOXA11 14525934 14973489 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GMNN HOXB7 14525934 14973489 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GMNN HOXC8 14525934 14973489 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GMNN HOXD10 14525934 14973489 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GMNN REPIN1 25348397 N/A physical interaction ComPPI
GMNN HDAC3 25348397 N/A physical interaction ComPPI
GMNN KAT7 25348397 N/A physical interaction ComPPI
GMNN SMARCA4 16024661 25348397 27898060 N/A physical interaction ComPPI,OmniPath
GMNN CASP3 25348397 N/A physical interaction ComPPI
GMNN CSNK2A1 25348397 N/A physical interaction ComPPI
GMNN SMARCA2 25348397 N/A physical interaction ComPPI
GMNN HDAC11 25348397 N/A physical interaction ComPPI
GMNN CDC20 25348397 N/A physical interaction ComPPI
GMNN FZR1 25348397 N/A physical interaction ComPPI
GMNN NCF1B 25348397 N/A physical interaction ComPPI
GMNN CDKN2A 25348397 N/A physical interaction ComPPI
GMNN CDH1 25348397 N/A physical interaction ComPPI
GMNN AURKA 25348397 N/A physical interaction ComPPI
GMNN ARNT 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GMNN IMPDH1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GMNN CDK2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
GMNN CCDC146 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GMNN ZNF439 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GMNN PNKD 25348397 N/A physical interaction ComPPI
GMNN C2ORF68 25348397 N/A physical interaction ComPPI
GMNN CCNA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GMNN CDK1 25348397 N/A physical interaction ComPPI
GMNN CDK3 25348397 N/A physical interaction ComPPI
GMNN ZMYM4 25348397 N/A physical interaction ComPPI
GMNN EWSR1 25348397 N/A physical interaction ComPPI
GMNN ATM 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GMNN CASP8 25348397 N/A physical interaction ComPPI
GMNN CLTB 25348397 N/A physical interaction ComPPI
GMNN SUPT6H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GMNN HERC4 25348397 N/A physical interaction ComPPI
GMNN EHMT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GMNN NPHP3 25348397 N/A physical interaction ComPPI
GMNN MID2 25348397 N/A physical interaction ComPPI
GMNN E2F5 25348397 N/A physical interaction ComPPI
GMNN MSL1 25348397 N/A physical interaction ComPPI
GMNN STN1 25348397 N/A physical interaction ComPPI
GMNN MTMR1 25348397 N/A physical interaction ComPPI
GMNN CKS2 25348397 N/A physical interaction ComPPI
GMNN CTC1 25348397 N/A physical interaction ComPPI
GMNN TFDP1 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
GMNN E2F4 25348397 N/A physical interaction ComPPI
GMNN CERK 25348397 N/A physical interaction ComPPI
GMNN MID1 25348397 N/A physical interaction ComPPI
GMNN TYK2 25348397 N/A physical interaction ComPPI
GMNN TGIF2LY 25348397 N/A physical interaction ComPPI
GMNN FAM83D 25348397 N/A physical interaction ComPPI
GMNN MYO5C 25348397 N/A physical interaction ComPPI
GMNN RUNDC3A 25348397 N/A physical interaction ComPPI
GMNN CEP192 25348397 N/A physical interaction ComPPI
GMNN HSPBP1 25348397 N/A physical interaction ComPPI
GMNN SKP2 25348397 N/A physical interaction ComPPI
GMNN MCIDAS 21543332 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,fluorescence microscopy ComPPI,IntAct
GMNN BAG4 25348397 N/A physical interaction ComPPI
GMNN ZNF785 25348397 N/A physical interaction ComPPI
GMNN KLHL22 25348397 N/A physical interaction ComPPI
GMNN POTEB3 25348397 N/A physical interaction ComPPI
GMNN TARBP1 25348397 N/A physical interaction ComPPI
GMNN HECTD1 25348397 N/A physical interaction ComPPI
GMNN ZZEF1 25348397 N/A physical interaction ComPPI
GMNN FBXO5 25348397 N/A pull down,physical interaction ComPPI
GMNN LNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GMNN GLIS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GMNN KANK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GMNN SAPCD2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HMMR GMNN 25348397 N/A physical interaction ComPPI
HOXC9 GMNN 14525934 14973489 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GMNN SPATA24 19515240 27898060 N/A N/A OmniPath
GMNN CDC6 15380092 27898060 inhibition N/A OmniPath
AURKA GMNN 23695679 27898060 N/A N/A OmniPath
CSNK2A1 GMNN 22615398 27898060 N/A N/A OmniPath

Visualization










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