GENE:CCNG2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CCNG2 |
| FullNmae | cyclin G2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:1593 |
| EnsembleID | ENSG00000138764 |
| Uniprot | Q16589 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CCNG2 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CCNG2 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CCNG2 | GO:0000079,GO:0000307,GO:0005634,GO:0005737,GO:0016538,GO:0044772,GO:0051301,GO:0051726 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CCNG2 | hsa:901 | path:hsa04068 | FoxO signaling pathway - Homo sapiens (human) |
| CCNG2 | hsa:901 | path:hsa04115 | p53 signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | CCNG2 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | CCNG2 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ESR1 | CCNG2 | 16608856 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | CCNG2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXO3 | CCNG2 | 18226221 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | CCNG2 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| HIF1A | CCNG2 | 18971253 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| FOXA1 | CCNG2 | 18971253 21878914 22596188 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | CCNG2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TFAP2C | CCNG2 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TP73 | CCNG2 | 21245298 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| FOXP3 | CCNG2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | CCNG2 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CCNG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CCNG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CCNG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | CCNG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CCNG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | CCNG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CCNG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CCNG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | CCNG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | CCNG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | CCNG2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| AHR | CCNG2 | 22596188 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| OTX2 | CCNG2 | 21047732 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | CCNG2 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000DDD35 | CCNG2 | 20371350 25309979 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,miRNA interference luciferase reporter assay | TarBase |
| URS00000F6E49 | CCNG2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000007FBA | CCNG2 | 25416803 27374211 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SKP1 | CCNG2 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | CCNG2 | 25348397 | N/A | physical interaction | ComPPI |
| PPP2R5C | CCNG2 | 25348397 | N/A | physical interaction | ComPPI |
| PPP2CA | CCNG2 | 11956189 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| PPP2R5E | CCNG2 | 25348397 | N/A | physical interaction | ComPPI |
| SKP2 | CCNG2 | 25348397 | N/A | physical interaction | ComPPI |
| PTPA | CCNG2 | 11956189 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| CCNG2 | PPP2R5B | 25348397 | N/A | physical interaction | ComPPI |
| CCNG2 | NRIP2 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| CCNG2 | TASOR2 | 25348397 | N/A | physical interaction | ComPPI |
| CCNG2 | EFHC2 | 25348397 | N/A | physical interaction | ComPPI |
| CCNG2 | NME2 | 25348397 | N/A | physical interaction | ComPPI |
| PPP2R5D | CCNG2 | 25348397 | N/A | physical interaction | ComPPI |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009C4DD0 | CCNG2 | 27087310 | direct interaction,inhibition | N/A | NPInter |
