GENE：CDCA7
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CDCA7 |
| FullNmae | cell division cycle associated 7 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:14628 |
| EnsembleID | ENSG00000144354 |
| Uniprot | Q9BWT1 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CDCA7 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CDCA7 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CDCA7 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CDCA7 | GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005829,GO:0006355,GO:0006915,GO:0042127 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | CDCA7 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | CDCA7 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | CDCA7 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | CDCA7 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | CDCA7 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | CDCA7 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CDCA7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CDCA7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CDCA7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CDCA7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CDCA7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CDCA7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | CDCA7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | CDCA7 | 16580749 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MYC | CDCA7 | 16580749 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000324096 | CDCA7 | 17699775 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000AA464 | CDCA7 | 20304954 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00002152A8 | CDCA7 | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS00001123BD | CDCA7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000017DBB8 | CDCA7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000007FBA | CDCA7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001F14FE | CDCA7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001D4A78 | CDCA7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065FDF | CDCA7 | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A4ABF | CDCA7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AFAD1 | CDCA7 | 20371350 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AKT1 | CDCA7 | 22135298 | phosphorylation | N/A | PhosphoSite |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| YWHAG | CDCA7 | 25348397 | N/A | physical interaction | ComPPI |
| YWHAZ | CDCA7 | 25348397 | N/A | physical interaction | ComPPI |
| PARP2 | CDCA7 | 21812934 24234451 25348397 | adp ribosylation reaction | protein array | ComPPI,IntAct |
| YWHAQ | CDCA7 | 25348397 | N/A | physical interaction | ComPPI |
| YWHAH | CDCA7 | 25348397 | N/A | physical interaction | ComPPI |
| SFN | CDCA7 | 25348397 | N/A | physical interaction | ComPPI |
| APP | CDCA7 | 25348397 | N/A | physical interaction | ComPPI |
| AKT1 | CDCA7 | 23166294 27898060 | inhibition | N/A | OmniPath |