Gene Information gene info

GENE:FANCF

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FANCF
FullNmae FA complementation group F
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3587
EnsembleID ENSG00000183161
Uniprot Q9NPI8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FANCF autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FANCF GO:0000785,GO:0003674,GO:0005515,GO:0005654,GO:0005654,GO:0006974,GO:0036297,GO:0043240,GO:0043240,GO:0043240

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FANCF hsa:2188 path:hsa03460 Fanconi anemia pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BLM FANCF 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FAAP24 FANCF 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCA FANCF 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCC FANCF 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCE FANCF 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCF FAAP100 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCF FAAP20 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCF FANCB 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCG FANCF 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCL FANCF 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCM FANCF 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
HES1 FANCF 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCF TOP3A 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCF FANCD2 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCF FANCI 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
RPA1 FANCF 26192618 association N/A ACSN
RPA2 FANCF 26192618 association N/A ACSN
RPA3 FANCF 26192618 association N/A ACSN
FANCF MRE11 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCF RAD50 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCF ATR 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 26192618 8020957 interaction type N/A ACSN
FANCF IRF8 19801548 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
FANCF PRDM1 20421211 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 FANCF 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 FANCF 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 FANCF 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA FANCF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FANCF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FANCF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FANCF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 FANCF 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 FANCF 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000042B108 FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001B0D1E FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000023F008 FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075AAA0 FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000050CCE0 FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFBE3 FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004214BB FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075ABF4 FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000277201 FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 FANCF 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B FANCF 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D FANCF 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013D17D FANCF 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 FANCF 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A FANCF 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E FANCF 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 FANCF 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000075D50C FANCF 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000045B99E FANCF 25416803 28735896 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NOTCH1 FANCF 25348397 N/A physical interaction ComPPI
CTBP1 FANCF 25348397 N/A physical interaction ComPPI
SPTAN1 FANCF 19102630 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FANCC FANCF 11063725 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SPTA1 FANCF 25348397 N/A physical interaction ComPPI
CTNNB1 FANCF 25348397 N/A physical interaction ComPPI
FANCE FANCF 12093742 24234451 25348397 association coimmunoprecipitation,physical interaction ComPPI,IntAct
FANCF MARK3 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FANCF OLFM2 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FANCF HES1 14525934 18550849 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
FANCF FANCA 11063725 12649160 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,three hybrid ComPPI,HPRD,IntAct
FANCF FANCG 11063725 11157805 12649160 14525934 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,physical interaction,three hybrid,two hybrid ComPPI,HPRD,IntAct
FANCF FANCM 17289582 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FANCF FANCL 25348397 N/A physical interaction ComPPI
FANCF CENPS 25348397 N/A physical interaction ComPPI
FANCF RMI1 25348397 N/A physical interaction ComPPI
FANCF FAAP20 25348397 N/A physical interaction ComPPI
FANCF CENPX 25348397 N/A physical interaction ComPPI
FANCF FAAP100 25348397 N/A physical interaction ComPPI
FANCF BRCA1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
GINS2 FANCF 25348397 N/A physical interaction ComPPI
FANCM FANCF 16116422 17289582 20064461 20347428 24910428 27898060 stimulant N/A OmniPath

Visualization