GENE:FANCF
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | FANCF |
| FullNmae | FA complementation group F |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:3587 |
| EnsembleID | ENSG00000183161 |
| Uniprot | Q9NPI8 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| FANCF | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| FANCF | GO:0000785,GO:0003674,GO:0005515,GO:0005654,GO:0005654,GO:0006974,GO:0036297,GO:0043240,GO:0043240,GO:0043240 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| FANCF | hsa:2188 | path:hsa03460 | Fanconi anemia pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | FANCF | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | FANCF | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | FANCF | 20953172 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| CEBPA | FANCF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | FANCF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | FANCF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | FANCF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | FANCF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | FANCF | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000042B108 | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001B0D1E | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000023F008 | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AAA0 | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000050CCE0 | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EFBE3 | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004214BB | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075ABF4 | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000277201 | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000272039 | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065D58 | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CF5F | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001DE669 | FANCF | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000486E0B | FANCF | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000047A67D | FANCF | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000013D17D | FANCF | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | FANCF | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E226A | FANCF | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | FANCF | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FC5B0 | FANCF | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D50C | FANCF | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS000045B99E | FANCF | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NOTCH1 | FANCF | 25348397 | N/A | physical interaction | ComPPI |
| CTBP1 | FANCF | 25348397 | N/A | physical interaction | ComPPI |
| SPTAN1 | FANCF | 19102630 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| FANCC | FANCF | 11063725 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| SPTA1 | FANCF | 25348397 | N/A | physical interaction | ComPPI |
| CTNNB1 | FANCF | 25348397 | N/A | physical interaction | ComPPI |
| FANCE | FANCF | 12093742 24234451 25348397 | association | coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| FANCF | MARK3 | 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
| FANCF | OLFM2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| FANCF | HES1 | 14525934 18550849 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
| FANCF | FANCA | 11063725 12649160 14525934 24234451 25348397 | physical association | coimmunoprecipitation,experimental interaction detection,physical interaction,three hybrid | ComPPI,HPRD,IntAct |
| FANCF | FANCG | 11063725 11157805 12649160 14525934 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,physical interaction,three hybrid,two hybrid | ComPPI,HPRD,IntAct |
| FANCF | FANCM | 17289582 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| FANCF | FANCL | 25348397 | N/A | physical interaction | ComPPI |
| FANCF | CENPS | 25348397 | N/A | physical interaction | ComPPI |
| FANCF | RMI1 | 25348397 | N/A | physical interaction | ComPPI |
| FANCF | FAAP20 | 25348397 | N/A | physical interaction | ComPPI |
| FANCF | CENPX | 25348397 | N/A | physical interaction | ComPPI |
| FANCF | FAAP100 | 25348397 | N/A | physical interaction | ComPPI |
| FANCF | BRCA1 | 24234451 25348397 29656893 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| GINS2 | FANCF | 25348397 | N/A | physical interaction | ComPPI |
| FANCM | FANCF | 16116422 17289582 20064461 20347428 24910428 27898060 | stimulant | N/A | OmniPath |
