Gene Information gene info

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GENE：FHOD1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FHOD1
FullNmae formin homology 2 domain containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17905
EnsembleID ENSG00000135723
Uniprot Q9Y613

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FHOD1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FHOD1 GO:0001725,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005856,GO:0007097,GO:0014704,GO:0016020,GO:0019904,GO:0030866,GO:0032059,GO:0042802,GO:0043621,GO:0045944,GO:0045944,GO:0051015,GO:0051492,GO:0051496,GO:0051660

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FHOD1 hsa:29109 path:hsa05132 Salmonella infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 FHOD1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 FHOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FHOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FHOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FHOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 FHOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FHOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FHOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 FHOD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000BE495 FHOD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D FHOD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000085F64 FHOD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 FHOD1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SRC FHOD1 22135298 phosphorylation N/A PhosphoSite
PRKG1 FHOD1 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
ROCK1 FHOD1 22135298 phosphorylation N/A PhosphoSite
FHOD1 RAC1 25361965 interaction type N/A PTMCode2
RAC1 FHOD1 25361965 interaction type N/A PTMCode2
FHOD1 PRKG1 25361965 interaction type N/A PTMCode2
PFN2 FHOD1 25361965 interaction type N/A PTMCode2
FHOD1 PFN2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNW1 FHOD1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L FHOD1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM21 FHOD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDC42 FHOD1 25348397 N/A two hybrid ComPPI
ACTG1 FHOD1 12665555 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
VCP FHOD1 25348397 N/A physical interaction ComPPI
ACTB FHOD1 25348397 N/A physical interaction ComPPI
RAC1 FHOD1 11590143 14525934 15051728 15642356 24234451 25348397 physical association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
BBS2 FHOD1 18000879 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EXOSC8 FHOD1 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
RNF5 FHOD1 14525934 14667819 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PICK1 FHOD1 25348397 N/A physical interaction ComPPI
HRAS FHOD1 18786395 24234451 25348397 27898060 N/A isothermal titration calorimetry,physical interaction ComPPI,IntAct,OmniPath
GRB2 FHOD1 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
JUN FHOD1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
ZMYND8 FHOD1 14525934 15095401 25348397 27898060 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD,OmniPath
PRKG1 FHOD1 14525934 15051728 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
YWHAZ FHOD1 25348397 N/A physical interaction ComPPI
NTRK1 FHOD1 25348397 N/A physical interaction ComPPI
APC FHOD1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
NCOA6 FHOD1 25348397 N/A physical interaction ComPPI
PFN2 FHOD1 12677009 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
FHOD1 ACTA1 12665555 14525934 14576350 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
FHOD1 CR2 14525934 15138285 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
FHOD1 LNPEP 12677009 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
FHOD1 RANBP2 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FHOD1 PPARG 25348397 N/A physical interaction ComPPI
FHOD1 BBS1 18000879 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FHOD1 BBS4 18000879 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FHOD1 BBS7 18000879 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FHOD1 UCHL5 25348397 N/A physical interaction ComPPI
FHOD1 PRMT2 25348397 N/A physical interaction ComPPI
FHOD1 GALE 25348397 N/A physical interaction ComPPI
FHOD1 TARS1 25348397 N/A physical interaction ComPPI
FHOD1 NLGN3 25348397 N/A physical interaction ComPPI
FHOD1 TMEM200A 25348397 N/A physical interaction ComPPI
FHOD1 SUOX 25348397 N/A physical interaction ComPPI
FHOD1 SYNE2 24234451 24880667 25348397 physical association anti bait coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
FHOD1 UBE2H 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
FHOD1 WNK1 20936779 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FHOD1 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
HSCB FHOD1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
FHOD1 FHOD1 14525934 14576350 15642356 18239683 18786395 24234451 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,molecular sieving,pull down,two hybrid HPRD,IntAct
PRKG1 FHOD1 15051728 18239683 21106951 27898060 stimulant N/A OmniPath
SRC FHOD1 24331927 27898060 N/A N/A OmniPath
ROCK1 FHOD1 18239683 27898060 stimulant N/A OmniPath

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