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GENE：GINS2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GINS2
FullNmae GINS complex subunit 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24575
EnsembleID ENSG00000131153
Uniprot Q9Y248

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GINS2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GINS2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GINS2 GO:0000727,GO:0000811,GO:0000811,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0006268,GO:0006268,GO:0071162,GO:0071162

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 GINS2 18414489 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation array,chromatin immunoprecipitation assay TFlink
ETS1 GINS2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 GINS2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 GINS2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 GINS2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 GINS2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 GINS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GINS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GINS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GINS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GINS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GINS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 GINS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 GINS2 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 GINS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075D814 GINS2 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 GINS2 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C GINS2 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 GINS2 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000006B702 GINS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD GINS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001938D9 GINS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E GINS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 GINS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA GINS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000096022 GINS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A GINS2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 GINS2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATR GINS2 22135298 phosphorylation N/A PhosphoSite
GINS2 MCM4 25361965 interaction type N/A PTMCode2
MCM4 GINS2 25361965 interaction type N/A PTMCode2
GINS2 GINS1 25361965 interaction type N/A PTMCode2
GINS1 GINS2 25361965 interaction type N/A PTMCode2
GINS2 MCM2 25361965 interaction type N/A PTMCode2
MCM2 GINS2 25361965 interaction type N/A PTMCode2
GINS2 GINS4 25361965 interaction type N/A PTMCode2
GINS4 GINS2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CSNK1G2 GINS2 25348397 N/A physical interaction ComPPI
GINS2 GINS4 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
GINS2 CHEK2 17525332 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GINS2 FANCF 25348397 N/A physical interaction ComPPI
GINS2 GINS3 25348397 N/A physical interaction ComPPI
GINS2 GINS1 17417653 17652513 24234451 25348397 physical association cosedimentation in solution,molecular sieving,x-ray crystallography,physical interaction,ion exchange chromatography ComPPI,IntAct
GINS2 EIF4H 25348397 N/A physical interaction ComPPI
GINS2 FERMT2 25348397 N/A physical interaction ComPPI
GINS2 AHSA1 25348397 N/A physical interaction ComPPI
GINS2 CAPN1 25348397 N/A physical interaction ComPPI
GINS2 CASP7 25348397 N/A physical interaction ComPPI
GINS2 CNDP2 25348397 N/A physical interaction ComPPI
GINS2 EEF2 25348397 N/A physical interaction ComPPI
GINS2 GSR 25348397 N/A physical interaction ComPPI
GINS2 MVD 25348397 N/A physical interaction ComPPI
GINS2 PEPD 25348397 N/A physical interaction ComPPI
GINS2 CTSA 25348397 N/A physical interaction ComPPI
GINS2 RPS6KA1 25348397 N/A physical interaction ComPPI
GINS2 MCM7 25348397 N/A physical interaction ComPPI
GINS2 SIK1 25348397 N/A physical interaction ComPPI
GINS2 LZIC 25348397 N/A physical interaction ComPPI
GINS2 H2AX 25348397 N/A physical interaction ComPPI
GINS2 MCMBP 22540012 24234451 24299456 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GINS2 PML 23589040 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct

Visualization










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