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GENE：PKD1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PKD1
FullNmae polycystin 1, transient receptor potential channel interacting
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9008
EnsembleID ENSG00000008710
Uniprot P98161

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PKD1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PKD1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PKD1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PKD1 GO:0000139,GO:0001502,GO:0001701,GO:0001822,GO:0001889,GO:0001892,GO:0002133,GO:0002133,GO:0005261,GO:0005262,GO:0005262,GO:0005515,GO:0005634,GO:0005737,GO:0005783,GO:0005794,GO:0005886,GO:0005886,GO:0005929,GO:0005929,GO:0005929,GO:0006611,GO:0006816,GO:0006816,GO:0007156,GO:0007160,GO:0007161,GO:0007204,GO:0007259,GO:0007259,GO:0007507,GO:0009653,GO:0009986,GO:0016020,GO:0016020,GO:0016055,GO:0016323,GO:0016328,GO:0018105,GO:0019901,GO:0019904,GO:0021510,GO:0021915,GO:0030155,GO:0030246,GO:0030660,GO:0031514,GO:0032092,GO:0034405,GO:0034703,GO:0034704,GO:0036303,GO:0042813,GO:0042994,GO:0043588,GO:0044325,GO:0045737,GO:0045944,GO:0048565,GO:0048754,GO:0048806,GO:0050982,GO:0051216,GO:0051290,GO:0051726,GO:0060170,GO:0060236,GO:0060428,GO:0060674,GO:0061136,GO:0070062,GO:0070062,GO:0070588,GO:0072164,GO:0072177,GO:0072205,GO:0072218,GO:0072237,GO:0072287,GO:0090162,GO:0198738,GO:2000045

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PKD1 PTK2 11113628 23180781 physical association cosedimentation through density gradient InnateDB
PKD1 CTNNB1 11113628 23180781 physical association anti tag coimmunoprecipitation,cosedimentation through density gradient InnateDB
PKD1 MAP3K1 20923779 23180781 physical association anti tag coimmunoprecipitation InnateDB
PKD1 TP53 20923779 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
PKD1 JAK2 20005715 interaction type N/A PSP
PKD1 ABL1 20005715 interaction type N/A PSP,SignaLink
PKD1 FYN 20005715 interaction type N/A PSP,SignaLink
PKD1 SRC 20005715 interaction type N/A PSP
PKD1 PTK2 20005715 interaction type N/A PSP,SignaLink
PKD1 SRC 11113628 18988627 20005715 N/A N/A SignaLink
PKD1 JAK2 12007403 18988627 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 PKD1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PKD1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF PKD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PKD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PKD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PKD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AR PKD1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 PKD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE PKD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D PKD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F PKD1 23344677 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000171525 PKD1 23294929 25416803 26701625 mrna cleavage,inhibition quantitative reverse transcription pcr,clip TarBase
URS00002E857A PKD1 23294929 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS0000321A1A PKD1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 PKD1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000007340 PKD1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 PKD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000AB32B PKD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 PKD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004818BD PKD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C PKD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 PKD1 22927820 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00002CBC6D PKD1 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000075D15B PKD1 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 PKD1 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA PKD1 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000009A9A2 PKD1 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 PKD1 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000032D69B PKD1 22927820 25416803 mrna cleavage,inhibition clip TarBase
URS000012A1DD PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000D6C3F PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000055BBE5 PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000496C56 PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000319E1 PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000037B2E0 PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002C02E4 PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000118224 PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004283FE PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075AEA5 PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075B13F PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000039A25B PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000008AA34 PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000080D0A PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 PKD1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA PKD1 22135298 phosphorylation N/A PhosphoSite
SRC PKD1 22135298 phosphorylation N/A PhosphoSite
PRKX PKD1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
KRT18 PKD1 11581269 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
DES PKD1 11581269 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
VIM PKD1 11581269 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
SRC PKD1 11113628 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SIAH1 PKD1 14525934 15284290 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
JUP PKD1 11274246 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
ACTN1 PKD1 11113628 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CDH1 PKD1 25348397 N/A in vitro,in vivo ComPPI
PKD1 PKD2 10097141 14525934 20168298 24234451 25348397 9192675 physical association anti tag coimmunoprecipitation,two hybrid,cross-linking study,experimental interaction detection,molecular sieving,nuclear magnetic resonance,pull down,static light scattering,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
PKD1 TLN1 11113628 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PKD1 VCL 11113628 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PKD1 PXN 25348397 N/A in vitro,in vivo ComPPI
PKD1 RGS7 10339594 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
PKD1 CTNNA1 11274246 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PKD1 CTNNB1 11274246 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PKD1 JAK2 12007403 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PKD1 COL2A1 11406351 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
PKD1 KRT8 11581269 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
PKD1 FN1 11752017 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
PKD1 COL1A1 25348397 N/A physical interaction ComPPI
PKD1 HDAC9 25348397 N/A physical interaction ComPPI
PKD1 MARK2 25348397 N/A physical interaction ComPPI
PKD1 ATP1A1 25348397 N/A physical interaction ComPPI
PKD1 CFTR 25348397 N/A physical interaction ComPPI
PKD1 JADE1 25348397 N/A physical interaction ComPPI
PKD1 PTK2 25348397 N/A physical interaction ComPPI
PKD1 GAN 25348397 N/A physical interaction ComPPI
PKD1 ATF7IP 14525934 15231748 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
PKD1 ABL1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PKD1 FYN 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PKD1 NPHP1 20856870 24234451 25348397 27898060 N/A isothermal titration calorimetry,nuclear magnetic resonance ComPPI,IntAct,OmniPath
BCAR1 PKD1 11113628 14525934 N/A experimental interaction detection HPRD
PKD1 KIN-10 16481400 24234451 physical association two hybrid IntAct
LTB4R2 PKD1 24234451 28298427 physical association ubiquitin reconstruction IntAct
SRC PKD1 11113628 21126580 27898060 stimulant N/A OmniPath
PKD1 PKD2 10097141 11140688 11901144 12937304 15060061 15692563 19556541 20168298 21642537 23390129 27898060 9171830 9192675 stimulant N/A OmniPath
PRKACA PKD1 10362514 17980165 27898060 N/A N/A OmniPath
PKD1 PKD2L1 15548533 16609150 27898060 stimulant N/A OmniPath
PKD1 PTK2 11113628 27898060 N/A N/A OmniPath
SP1 PKD1 17890878 27898060 stimulant N/A OmniPath
PRKX PKD1 17980165 27898060 stimulant N/A OmniPath

Visualization










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