GENE:POR
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | POR |
FullNmae | cytochrome p450 oxidoreductase |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:9208 |
EnsembleID | ENSG00000127948 |
Uniprot | P16435 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
POR | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
POR | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
POR | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
POR | GO:0003958,GO:0003958,GO:0003958,GO:0005515,GO:0005789,GO:0005829,GO:0006805,GO:0009725,GO:0010181,GO:0016020,GO:0022900,GO:0032770,GO:0043231,GO:0050660,GO:0050661,GO:0090346 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ESR1 | POR | 21393444 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay,electrophoretic mobility shift assay | TFlink |
ETS1 | POR | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMAD3 | POR | 21393444 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay | TFlink |
SMAD4 | POR | 21393444 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay | TFlink |
YBX1 | POR | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
THRA | POR | 21393444 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay,electrophoretic mobility shift assay | TFlink |
THRB | POR | 21393444 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay | TFlink |
SMARCA4 | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | POR | 10864447 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
GATA2 | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SP1 | POR | 10864447 21900384 8660656 | trascriptional regulation,stimulation | inferred by curator | TFlink |
DAND5 | POR | 10864447 21900384 8660656 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000237AF9 | POR | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00002B7450 | POR | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000160683 | POR | 23905773 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
NDUFB9 | POR | 25348397 | N/A | physical interaction | ComPPI |
STAT1 | POR | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
CYCS | POR | 18230729 24234451 25348397 27898060 | N/A | physical interaction,enzymatic study | ComPPI,IntAct,OmniPath |
HMOX1 | POR | 12626517 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
PLOD3 | POR | 25348397 | N/A | physical interaction | ComPPI |
VAPA | POR | 25348397 | N/A | physical interaction | ComPPI |
NTRK1 | POR | 25348397 | N/A | physical interaction | ComPPI |
XRCC6 | POR | 14525934 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
EVC2 | POR | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
EWSR1 | POR | 25348397 | N/A | physical interaction | ComPPI |
XPO1 | POR | 25348397 | N/A | physical interaction | ComPPI |
SYVN1 | POR | 25348397 | N/A | physical interaction | ComPPI |
FANCC | POR | 25348397 27898060 9787138 | N/A | physical interaction | ComPPI,OmniPath |
CYB5A | POR | 14525934 25348397 9398194 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
CYP17A1 | POR | 14525934 25348397 27898060 9888582 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
INSIG1 | POR | 25348397 | N/A | physical interaction | ComPPI |
DERL1 | POR | 25348397 | N/A | physical interaction | ComPPI |
PGRMC1 | POR | 21081644 24234451 25348397 | colocalization,association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy | ComPPI,IntAct |
CYP3A4 | POR | 25348397 | N/A | physical interaction | ComPPI |
POR | CYP2E1 | 14525934 25348397 9398194 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
POR | SRPRB | 25348397 | N/A | physical interaction | ComPPI |
POR | UBXN6 | 25348397 | N/A | physical interaction | ComPPI |
POR | ATL3 | 25348397 | N/A | physical interaction | ComPPI |
POR | NDUFV1 | 25348397 | N/A | physical interaction | ComPPI |
POR | PLOD1 | 25348397 | N/A | physical interaction | ComPPI |
POR | CTDNEP1 | 25348397 | N/A | physical interaction | ComPPI |
WG | POR | 24234451 25348397 | physical association | experimental interaction detection,physical interaction | ComPPI,IntAct |
PIP | POR | 14605208 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
POR | CYP4P2 | 14605208 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
POR | WNT5 | 25348397 | N/A | physical interaction | ComPPI |
POR | WNT4 | 25348397 | N/A | physical interaction | ComPPI |
WNT2 | POR | 25348397 | N/A | physical interaction | ComPPI |