Gene Information gene info

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GENE：RFC3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RFC3
FullNmae replication factor C subunit 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9971
EnsembleID ENSG00000133119
Uniprot P40938

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RFC3 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RFC3 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RFC3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RFC3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RFC3 GO:0000731,GO:0003677,GO:0003689,GO:0003689,GO:0003689,GO:0005515,GO:0005634,GO:0005654,GO:0005663,GO:0005663,GO:0005663,GO:0005663,GO:0006260,GO:0006261,GO:0006261,GO:0006271,GO:0006281,GO:0008094,GO:0016887,GO:0017116,GO:0031390,GO:0032508,GO:0046683,GO:1900264

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RFC3 hsa:5983 path:hsa03030 DNA replication - Homo sapiens (human)
RFC3 hsa:5983 path:hsa03410 Base excision repair - Homo sapiens (human)
RFC3 hsa:5983 path:hsa03420 Nucleotide excision repair - Homo sapiens (human)
RFC3 hsa:5983 path:hsa03430 Mismatch repair - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RFC1 RFC3 14624239 26192618 interaction type N/A ACSN
RFC2 RFC3 14624239 26192618 interaction type N/A ACSN
RFC3 RFC5 14624239 26192618 interaction type N/A ACSN
RFC4 RFC3 14624239 26192618 interaction type N/A ACSN
RFC3 PCNA 26192618 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
E2F4 RFC3 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 RFC3 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RFC3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 RFC3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 RFC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RFC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RFC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RFC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RFC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 RFC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RFC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RFC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 RFC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 RFC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 RFC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AHR RFC3 12417031 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RFC3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000DDD35 RFC3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F RFC3 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ORC1 RFC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SNW1 RFC3 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L RFC3 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DAXX RFC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP20 RFC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PCNA RFC3 10051561 12171929 14525934 14657243 25348397 9092549 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
VCP RFC3 25348397 N/A physical interaction ComPPI
RAD21 RFC3 25348397 N/A physical interaction ComPPI
KEAP1 RFC3 25348397 N/A physical interaction ComPPI
KHDRBS2 RFC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ANKRD40 RFC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DDIT4L RFC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NF2 RFC3 25348397 N/A physical interaction ComPPI
PICK1 RFC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RPL10 RFC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
JUN RFC3 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
UBC RFC3 25348397 N/A physical interaction ComPPI
NTRK1 RFC3 25348397 N/A physical interaction ComPPI
PVR RFC3 25348397 N/A physical interaction ComPPI
RPA1 RFC3 25348397 N/A physical interaction ComPPI
RFC2 RFC3 24234451 25348397 9488738 physical association cosedimentation in solution,physical interaction ComPPI,IntAct
CHTF18 RFC3 25348397 N/A physical interaction ComPPI
DSCC1 RFC3 25348397 N/A physical interaction ComPPI
DERPC RFC3 25348397 N/A physical interaction,in vivo ComPPI
CHTF8 RFC3 25348397 N/A physical interaction,in vivo ComPPI
MYC RFC3 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
HNRNPU RFC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FSCN1 RFC3 20603015 24234451 25348397 association pull down ComPPI,IntAct
NFATC2 RFC3 25348397 N/A physical interaction ComPPI
RPA2 RFC3 25348397 N/A physical interaction ComPPI
RPA3 RFC3 25348397 N/A physical interaction ComPPI
RPS6 RFC3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EGFR RFC3 25348397 N/A physical interaction ComPPI
PURA RFC3 25348397 N/A physical interaction ComPPI
H3C1 RFC3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
IBTK RFC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KHDRBS3 RFC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RFC5 RFC3 25348397 N/A physical interaction ComPPI
PURB RFC3 25348397 N/A physical interaction ComPPI
NOP56 RFC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARFGAP1 RFC3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RFC4 RFC3 14525934 24234451 25348397 8692848 9488738 association,physical association experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
MCM3 RFC3 25348397 N/A physical interaction ComPPI
RFC3 RFC1 14525934 24234451 25348397 8692848 9488738 association,physical association cosedimentation in solution,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
RFC3 RAD17 14624239 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RFC3 BRD4 25348397 N/A physical interaction ComPPI
RFC3 MEPCE 25348397 N/A physical interaction ComPPI
RFC3 FAN1 25348397 N/A physical interaction ComPPI
RFC3 MESD 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RFC3 SMARCAD1 25348397 N/A physical interaction ComPPI
RFC3 HDGF 25348397 N/A physical interaction ComPPI
RFC3 FBXO6 25348397 N/A physical interaction ComPPI
RFC3 RPP40 25348397 N/A physical interaction ComPPI
RFC3 TP53 25348397 N/A physical interaction ComPPI
RFC3 CCDC8 25348397 N/A physical interaction ComPPI
RFC3 IFI16 25348397 N/A physical interaction ComPPI
RFC3 NCL 25348397 N/A physical interaction ComPPI
RFC3 G3BP1 25348397 N/A physical interaction ComPPI
RFC3 MCM9 25348397 N/A physical interaction ComPPI
RFC3 PHLDA3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RFC3 INCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSCB RFC3 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
TANK RFC3 24234451 30561431 association virotrap IntAct
TRADD RFC3 24234451 30561431 association virotrap IntAct

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