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GENE：RIPK2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RIPK2
FullNmae receptor interacting serine/threonine kinase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10020
EnsembleID ENSG00000104312
Uniprot O43353

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RIPK2 pyroptosis 36549449 The results showed that RIPK2 knockdown could repress DBDPE-induced NOD-like receptor signaling pathway upregulation, inhibit NLRP3 inflammasome activation, and decrease HAECs pyroptosis. retulator signature
RIPK2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RIPK2 autophagy 33204717 Besides, we predicted that both MET and RIPK2 promote autophagy in pancreatic ductal adenocarcinoma by gene set enrichment analysis. retulator signature
RIPK2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
RIPK2 GO:0001961,GO:0002250,GO:0002827,GO:0004674,GO:0004674,GO:0004706,GO:0004715,GO:0005102,GO:0005515,GO:0005524,GO:0005737,GO:0005783,GO:0005829,GO:0005829,GO:0005856,GO:0005886,GO:0006915,GO:0006954,GO:0007165,GO:0007249,GO:0007254,GO:0010800,GO:0016310,GO:0019221,GO:0030274,GO:0031398,GO:0031398,GO:0031663,GO:0031982,GO:0032092,GO:0032722,GO:0032727,GO:0032728,GO:0032729,GO:0032731,GO:0032735,GO:0032743,GO:0032755,GO:0032760,GO:0032991,GO:0032991,GO:0033080,GO:0033092,GO:0033138,GO:0034134,GO:0034142,GO:0035591,GO:0035739,GO:0042742,GO:0042802,GO:0042803,GO:0043065,GO:0043123,GO:0043123,GO:0043330,GO:0045087,GO:0045087,GO:0045087,GO:0045627,GO:0045944,GO:0046330,GO:0050700,GO:0050700,GO:0050731,GO:0050830,GO:0050852,GO:0050852,GO:0051092,GO:0051092,GO:0051260,GO:0060907,GO:0070371,GO:0070374,GO:0070427,GO:0070431,GO:0070555,GO:0070671,GO:0070673,GO:0071223,GO:0071224,GO:0071225,GO:0089720,GO:0097202,GO:0098792,GO:0106310,GO:1902523,GO:1904417,GO:2000563

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RIPK2 hsa:8767 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
RIPK2 hsa:8767 path:hsa04722 Neurotrophin signaling pathway - Homo sapiens (human)
RIPK2 hsa:8767 path:hsa05131 Shigellosis - Homo sapiens (human)
RIPK2 hsa:8767 path:hsa05132 Salmonella infection - Homo sapiens (human)
RIPK2 hsa:8767 path:hsa05152 Tuberculosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RIPK2 MAP3K7 17348859 17947236 17965022 18079694 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 TLR4 15691841 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 IRAK1 15691841 16824733 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 TRAF6 15691841 16824733 23180781 physical association anti tag coimmunoprecipitation InnateDB
TICAM1 RIPK2 15814722 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 TLR2 11894098 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 TRIP6 15657077 23180781 physical association anti tag coimmunoprecipitation InnateDB
RAF1 RIPK2 10559258 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 CFLAR 23180781 9575181 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 NOD2 16492792 16552041 16714539 17054981 19266573 19337385 19464198 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
RIPK2 CARD9 17187069 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 PYCARD 14634131 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
RIPK2 CASP1 11051551 11536016 14634131 15039421 16585594 23180781 physical association anti tag coimmunoprecipitation InnateDB
CARD6 RIPK2 12775719 16418290 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 RIPK2 10880512 16824733 19337385 23180781 phosphorylation reaction,physical association affinity chromatography technology,anti tag coimmunoprecipitation,two hybrid,in-gel kinase assay InnateDB
TAB1 RIPK2 18079694 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 TAB2 18079694 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 BIRC2 19464198 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
RIPK2 BIRC3 19464198 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
RIPK2 XIAP 19667203 23180781 physical association anti tag coimmunoprecipitation InnateDB
NOD2 RIPK2 19667203 23180781 24790089 physical association anti tag coimmunoprecipitation InnateDB
NOD1 RIPK2 19337385 19667203 23180781 24958724 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
RIPK2 IRF4 18188453 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF3 RIPK2 20389019 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAVS RIPK2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 TRAF2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 IKBKG 18079694 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKG RIPK2 21552281 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF4 RIPK2 23180781 24670424 physical association anti tag coimmunoprecipitation,proximity ligation assay InnateDB
PELI3 RIPK2 23180781 23892723 physical association anti tag coimmunoprecipitation InnateDB
XIAP RIPK2 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
BCL10 RIPK2 20005715 interaction type N/A PSP
BIRC2 RIPK2 20005715 interaction type N/A PSP
NOD1 RIPK2 20005715 interaction type N/A PSP
NOD2 RIPK2 20005715 interaction type N/A PSP
TRAF1 RIPK2 20005715 interaction type N/A PSP
TRAF2 RIPK2 20005715 interaction type N/A PSP
TRAF5 RIPK2 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
E2F4 RIPK2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 RIPK2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 RIPK2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 RIPK2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 RIPK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RIPK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RIPK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RIPK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RIPK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RIPK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RIPK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RIPK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RIPK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 RIPK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 RIPK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 RIPK2 19693652 trascriptional regulation,stimulation inferred by curator TFlink
RELA RIPK2 19693652 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 RIPK2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 RIPK2 25416803 28097098 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
RIPK2 RIPK2 22135298 phosphorylation N/A PhosphoSite
RIPK2 BIRC2 25361965 interaction type N/A PTMCode2
BIRC2 RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 CARD6 25361965 interaction type N/A PTMCode2
CARD6 RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 TRAF5 25361965 interaction type N/A PTMCode2
TRAF5 RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 BIRC3 25361965 interaction type N/A PTMCode2
BIRC3 RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 BCL10 25361965 interaction type N/A PTMCode2
BCL10 RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 CFLAR 25361965 interaction type N/A PTMCode2
CFLAR RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 TRAF6 25361965 interaction type N/A PTMCode2
TRAF6 RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 XIAP 25361965 interaction type N/A PTMCode2
XIAP RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 CASP8 25361965 interaction type N/A PTMCode2
CASP8 RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 IKBKG 25361965 interaction type N/A PTMCode2
IKBKG RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 IRAK1 25361965 interaction type N/A PTMCode2
IRAK1 RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 CD40 25361965 interaction type N/A PTMCode2
CD40 RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 CARD16 25361965 interaction type N/A PTMCode2
CARD16 RIPK2 25361965 interaction type N/A PTMCode2
NGFR RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 NGFR 25361965 interaction type N/A PTMCode2
TNFRSF1A RIPK2 25361965 interaction type N/A PTMCode2
RIPK2 TNFRSF1A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I RIPK2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HSPA8 RIPK2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
HSPA2 RIPK2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CEP43 RIPK2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
VIM RIPK2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ACTG1 RIPK2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TUBB RIPK2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
TRAF6 RIPK2 14525934 25348397 9642260 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CALM1 RIPK2 25348397 N/A tandem affinity purification ComPPI
XIAP RIPK2 19667203 21931591 24234451 25348397 25416956 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SMAD4 RIPK2 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
IRF4 RIPK2 25348397 N/A physical interaction ComPPI
GAPDH RIPK2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
UBC RIPK2 25348397 N/A physical interaction ComPPI
HSP90AA1 RIPK2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
ENO1 RIPK2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CASP1 RIPK2 14525934 24234451 25348397 9705938 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
PSMA6 RIPK2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CASP8 RIPK2 14525934 25348397 9575181 N/A experimental interaction detection,in vivo ComPPI,HPRD
TRAF3 RIPK2 23333941 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
MAP3K4 RIPK2 25348397 N/A physical interaction ComPPI
TNFRSF1A RIPK2 14525934 25348397 9642260 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
VDAC1 RIPK2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IRAK1 RIPK2 14525934 15691841 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
NFATC2 RIPK2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TRAF1 RIPK2 14525934 24234451 25348397 9705938 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
TRAF2 RIPK2 14525934 21903422 24234451 25348397 9705938 physical association anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
PRMT2 RIPK2 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TRAF5 RIPK2 14525934 25348397 9642260 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
NGFR RIPK2 11487608 14525934 16498402 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PHB2 RIPK2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CHUK RIPK2 25348397 N/A physical interaction ComPPI
TLR2 RIPK2 11894098 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TLR4 RIPK2 14525934 15691841 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RIPK1 RIPK2 25348397 N/A physical interaction ComPPI
RIPK2 CD40 14525934 25348397 9642260 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RIPK2 BIRC2 14525934 21931591 24234451 25348397 9642260 ubiquitination reaction,physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,enzymatic study,in vivo ComPPI,HPRD,IntAct
RIPK2 NOD2 11087742 14525934 21931826 22829933 24234451 25348397 association,physical association anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
RIPK2 NOD1 10224040 10329646 12459189 14525934 17054981 24234451 25348397 29997244 physical association anti tag coimmunoprecipitation,bioluminescence resonance energy transfer,two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
RIPK2 CARD6 12775719 14525934 16418290 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
RIPK2 CARD16 11432859 11536016 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RIPK2 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RIPK2 KCTD12 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RIPK2 RPL38 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RIPK2 BIRC3 21931591 24234451 25348397 ubiquitination reaction,physical association anti tag coimmunoprecipitation,pull down,physical interaction,enzymatic study ComPPI,IntAct
RIPK2 IKBKG 10880512 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
RIPK2 MAP3K7 25348397 N/A physical interaction ComPPI
RIPK2 TAB1 25348397 N/A physical interaction ComPPI
RIPK2 TAB2 25348397 N/A physical interaction ComPPI
RIPK2 MAVS 21903422 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RIPK2 NAT16 25348397 N/A physical interaction ComPPI
RIPK2 RNF31 25348397 N/A physical interaction ComPPI
RIPK2 CASP12 25348397 N/A physical interaction ComPPI
RIPK2 TRAF4 25348397 N/A physical interaction ComPPI
RIPK2 LRRK2 25348397 N/A physical interaction ComPPI
RIPK2 PELI3 25348397 N/A physical interaction ComPPI
RIPK2 KDM3A 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RIPK2 SHMT2 25348397 N/A physical interaction ComPPI
RIPK2 MOV10 25348397 N/A physical interaction ComPPI
RIPK2 NXF1 25348397 N/A physical interaction ComPPI
RIPK2 HSPA1L 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK2 HSPA6 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK2 MYH10 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK2 HADHB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK2 GEMIN4 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK2 TUBB2B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK2 TUBB4A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK2 MYH9 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK2 TUBA3C 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK2 MYO1D 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
RIPK2 ATP5F1D 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RIPK2 ECHS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RIPK2 GXYLT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RIPK2 PCMT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RIPK2 FABP5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RIPK2 KIF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RIPK2 SOD2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RIPK2 RPL36 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RIPK2 PSMB5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RIPK2 PSMA7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RIPK2 EZR 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RIPK2 HNRNPA3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CFLAR RIPK2 14525934 25348397 9575181 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
BCL10 RIPK2 14525934 14638696 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RPS14 RIPK2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RIPK2 RIPK2 14743216 24234451 25416956 physical association two hybrid array,tandem affinity purification,two hybrid prey pooling approach IntAct
CALM2 RIPK2 14743216 24234451 physical association tandem affinity purification IntAct
CASP1 RIPK2 10329646 11051551 11536016 12459189 14634131 15039421 16585594 27898060 9705938 N/A N/A OmniPath
MAP3K7 RIPK2 10702308 15075345 17079228 17348859 17947236 17965022 18079694 27898060 N/A N/A OmniPath
RIPK2 MAP3K7 10702308 15075345 17079228 17348859 17947236 17965022 18079694 27898060 stimulant N/A OmniPath
NOD2 RIPK2 11087742 11894098 15107016 15620648 16203728 16492792 16552041 16714539 17054981 17355968 18775659 19266573 19337385 19464198 19592251 19667203 21097508 21123652 22470564 22607974 22665475 22829933 24790089 26670046 27898060 inhibition,stimulant N/A OmniPath
RIPK2 TRAF2 21903422 27898060 9705938 N/A N/A OmniPath
TICAM1 RIPK2 15814722 27898060 N/A N/A OmniPath
PYCARD RIPK2 14634131 27898060 N/A N/A OmniPath
RIPK2 BCL10 10825200 14638696 14695475 27898060 stimulant N/A OmniPath
RIPK2 TRAF6 10500182 15691841 16824733 17947236 18329614 21097508 27898060 8837778 9642260 N/A N/A OmniPath
TRAF6 RIPK2 10500182 15691841 16824733 17947236 18329614 21097508 27898060 8837778 9642260 N/A N/A OmniPath
MAVS RIPK2 21903422 27898060 N/A N/A OmniPath
TLR4 RIPK2 15691841 27898060 N/A N/A OmniPath
RIPK2 XIAP 19667203 21931591 22607974 22815893 23818254 25416956 27898060 N/A N/A OmniPath
XIAP RIPK2 19667203 21931591 22607974 22815893 23818254 25416956 27898060 stimulant N/A OmniPath
IKBKG RIPK2 10329646 10880512 11087742 11463746 15620648 17947236 17965022 18079694 21552281 27898060 N/A N/A OmniPath
RIPK2 TLR2 11894098 27898060 N/A N/A OmniPath
RIPK2 MAPK14 15692051 17947236 17965022 27898060 stimulant N/A OmniPath
RIPK2 IRF5 22412986 27898060 stimulant N/A OmniPath
RIPK2 NFKBIA 10195894 10329646 10880512 11087742 12514169 16493424 17965022 27898060 7739562 7796813 7862124 7878466 8657102 N/A N/A OmniPath
RIPK2 RAF1 10559258 27898060 N/A N/A OmniPath
RIPK2 TAB2 18079694 27898060 stimulant N/A OmniPath
BIRC2 RIPK2 19464198 21931591 27898060 9642260 9705938 stimulant N/A OmniPath
RIPK2 BIRC3 19464198 21931591 27898060 9705938 N/A N/A OmniPath
BIRC3 RIPK2 19464198 21931591 27898060 9705938 stimulant N/A OmniPath
NLRC4 RIPK2 15107016 27898060 inhibition N/A OmniPath
RIPK2 UBE2N 17947236 27898060 8837778 N/A N/A OmniPath
UBE2N RIPK2 17947236 27898060 8837778 N/A N/A OmniPath
RIPK2 CFLAR 27898060 9575181 N/A N/A OmniPath
RIPK2 TAB1 18079694 27898060 stimulant N/A OmniPath
RIPK2 MAPK8 15692051 17186025 17947236 17965022 27898060 stimulant N/A OmniPath
CARD16 RIPK2 11432859 11536016 27898060 N/A N/A OmniPath
IRAK1 RIPK2 15691841 16824733 27898060 N/A N/A OmniPath
RIPK2 TRAF3 20389019 23333941 27898060 stimulant N/A OmniPath
TRAF3 RIPK2 20389019 23333941 27898060 N/A N/A OmniPath
RIPK2 IKBKB 10094049 10195894 10329646 10837071 10880512 11087742 11463746 15327770 15620648 15691841 16186825 16260493 16493424 17947236 17965022 27898060 stimulant N/A OmniPath
PELI3 RIPK2 23892723 27898060 N/A N/A OmniPath
RIPK2 CARD6 12775719 16418290 27898060 N/A N/A OmniPath
CARD6 RIPK2 12775719 16418290 27898060 stimulant N/A OmniPath
UBE2V1 RIPK2 17947236 27898060 N/A N/A OmniPath
IRF4 RIPK2 18188453 24670424 27898060 N/A N/A OmniPath
NOD1 RIPK2 10224040 10329646 10880512 11463746 11894098 12459189 15107016 16517750 17054981 19337385 19667203 22470564 23300079 24958724 27898060 inhibition,stimulant N/A OmniPath
RIPK2 TRIP6 15657077 27898060 N/A N/A OmniPath
RIPK2 CARD9 17187069 17486093 27898060 N/A N/A OmniPath
ERBIN RIPK2 16203728 16714539 27898060 inhibition N/A OmniPath

Visualization










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