Gene Information gene info

  1. Home

GENE：TXNRD2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TXNRD2
FullNmae thioredoxin reductase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18155
EnsembleID ENSG00000184470
Uniprot Q9NNW7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TXNRD2 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TXNRD2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TXNRD2 GO:0000305,GO:0004791,GO:0004791,GO:0005515,GO:0005737,GO:0005739,GO:0005739,GO:0005759,GO:0005829,GO:0005829,GO:0009410,GO:0010269,GO:0030424,GO:0030425,GO:0042803,GO:0043025,GO:0044877,GO:0045454,GO:0045454,GO:0050660,GO:0055093,GO:0098869

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TXNRD2 hsa:10587 path:hsa00450 Selenocompound metabolism - Homo sapiens (human)
TXNRD2 hsa:10587 path:hsa05200 Pathways in cancer - Homo sapiens (human)
TXNRD2 hsa:10587 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR TXNRD2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TXNRD2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TXNRD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TXNRD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TXNRD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TXNRD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TXNRD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TXNRD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 TXNRD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TXNRD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TXNRD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TXNRD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA TXNRD2 21203553 rna interference,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay miRSponge
URS00002075FA TXNRD2 21203553 25416803 27505139 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002B7450 TXNRD2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 TXNRD2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075AB14 TXNRD2 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 TXNRD2 22291592 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BCAS2 TXNRD2 25348397 N/A physical interaction ComPPI
PSMC3 TXNRD2 25348397 N/A physical interaction ComPPI
PPP1R3C TXNRD2 25348397 N/A physical interaction ComPPI
NCOR1 TXNRD2 14525934 15598662 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
NCOA6 TXNRD2 25348397 N/A physical interaction ComPPI
AKR1B1 TXNRD2 25348397 N/A physical interaction ComPPI
RDX TXNRD2 25348397 N/A physical interaction ComPPI
TADA3 TXNRD2 25348397 N/A physical interaction ComPPI
NCOA2 TXNRD2 25348397 N/A physical interaction ComPPI
TXNRD1 TXNRD2 25348397 N/A physical interaction ComPPI
EZR TXNRD2 25348397 N/A physical interaction ComPPI
NDUFA13 TXNRD2 24234451 24344204 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

Visualization










  Return