GENE:DHRS3
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | DHRS3 |
FullNmae | dehydrogenase/reductase 3 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:17693 |
EnsembleID | ENSG00000162496 |
Uniprot | O75911 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
DHRS3 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
DHRS3 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
DHRS3 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
DHRS3 | GO:0000166,GO:0001523,GO:0001523,GO:0003151,GO:0004745,GO:0005789,GO:0005811,GO:0007601,GO:0009055,GO:0022900,GO:0030278,GO:0042572,GO:0042622,GO:0048385,GO:0048387,GO:0052650,GO:0060021,GO:0060349,GO:0060411 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
DHRS3 | hsa:9249 | path:hsa00830 | Retinol metabolism - Homo sapiens (human) |
DHRS3 | hsa:9249 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
DHRS3 | hsa:9249 | path:hsa01240 | Biosynthesis of cofactors - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | DHRS3 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ESR1 | DHRS3 | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | DHRS3 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA1 | DHRS3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | DHRS3 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
YBX1 | DHRS3 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXP3 | DHRS3 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
SMARCA4 | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXP1 | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
MED21 | DHRS3 | 25348397 | N/A | physical interaction | ComPPI |
HNRNPL | DHRS3 | 25348397 | N/A | physical interaction | ComPPI |
ELAVL1 | DHRS3 | 25348397 | N/A | physical interaction | ComPPI |
C5AR2 | DHRS3 | 25348397 | N/A | physical interaction | ComPPI |
TLR5 | DHRS3 | 25348397 | N/A | physical interaction | ComPPI |
IL4R | DHRS3 | 25348397 | N/A | physical interaction | ComPPI |
DHRS3 | IL17RC | 25348397 | N/A | physical interaction | ComPPI |