GENE:DHRS3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | DHRS3 |
| FullNmae | dehydrogenase/reductase 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17693 |
| EnsembleID | ENSG00000162496 |
| Uniprot | O75911 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| DHRS3 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| DHRS3 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| DHRS3 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| DHRS3 | GO:0000166,GO:0001523,GO:0001523,GO:0003151,GO:0004745,GO:0005789,GO:0005811,GO:0007601,GO:0009055,GO:0022900,GO:0030278,GO:0042572,GO:0042622,GO:0048385,GO:0048387,GO:0052650,GO:0060021,GO:0060349,GO:0060411 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| DHRS3 | hsa:9249 | path:hsa00830 | Retinol metabolism - Homo sapiens (human) |
| DHRS3 | hsa:9249 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| DHRS3 | hsa:9249 | path:hsa01240 | Biosynthesis of cofactors - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | DHRS3 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | DHRS3 | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | DHRS3 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | DHRS3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | DHRS3 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | DHRS3 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | DHRS3 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | DHRS3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MED21 | DHRS3 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | DHRS3 | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | DHRS3 | 25348397 | N/A | physical interaction | ComPPI |
| C5AR2 | DHRS3 | 25348397 | N/A | physical interaction | ComPPI |
| TLR5 | DHRS3 | 25348397 | N/A | physical interaction | ComPPI |
| IL4R | DHRS3 | 25348397 | N/A | physical interaction | ComPPI |
| DHRS3 | IL17RC | 25348397 | N/A | physical interaction | ComPPI |
