Gene Information gene info

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GENE：CLK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CLK1
FullNmae CDC like kinase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2068
EnsembleID ENSG00000013441
Uniprot P49759

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CLK1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CLK1 GO:0004674,GO:0004674,GO:0004712,GO:0004713,GO:0004715,GO:0005515,GO:0005524,GO:0005634,GO:0016310,GO:0018108,GO:0043484,GO:0043484,GO:0106310

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CLK1 hsa:1195 path:hsa05134 Legionellosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ISG15 CLK1 16009940 23180781 physical association unspecified method InnateDB
SRPK1 CLK1 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
AR CLK1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CLK1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 CLK1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CLK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CLK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CLK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CLK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CLK1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 CLK1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 CLK1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000021D7C8 CLK1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CLK1 ABL1 22135298 phosphorylation N/A PhosphoSite
CLK1 RBM17 22135298 phosphorylation N/A PhosphoSite
CLK1 PTPN1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
BAG3 CLK1 25348397 N/A physical interaction ComPPI
ISG15 CLK1 25348397 N/A physical interaction ComPPI
NPM1 CLK1 25348397 N/A physical interaction ComPPI
HSPBP1 CLK1 25348397 N/A physical interaction ComPPI
IMPDH2 CLK1 25348397 N/A physical interaction ComPPI
KRTAP10-7 CLK1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LMNA CLK1 25348397 N/A physical interaction ComPPI
YWHAG CLK1 14525934 15324660 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
PPP1CB CLK1 25348397 N/A physical interaction ComPPI
PRKDC CLK1 25348397 N/A physical interaction ComPPI
KHDRBS1 CLK1 25348397 N/A physical interaction ComPPI
RBM39 CLK1 25348397 N/A physical interaction ComPPI
RBBP6 CLK1 25348397 N/A physical interaction ComPPI
SF3B1 CLK1 25348397 N/A physical interaction ComPPI
PTPN22 CLK1 25348397 N/A physical interaction ComPPI
ARHGEF12 CLK1 25348397 N/A physical interaction ComPPI
CUL3 CLK1 25348397 N/A physical interaction ComPPI
NCOR1 CLK1 25348397 N/A physical interaction ComPPI
ENO1 CLK1 25348397 N/A physical interaction ComPPI
CDCP1 CLK1 25348397 N/A physical interaction ComPPI
PTPN1 CLK1 10480872 11579209 14525934 24234451 25348397 phosphorylation reaction experimental interaction detection,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
STIP1 CLK1 25348397 N/A physical interaction ComPPI
CLK2 CLK1 25348397 N/A physical interaction ComPPI
CLK1 SRSF1 14525934 25348397 8617202 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
CLK1 UBL5 12705895 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CLK1 PIAS4 14525934 15383276 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CLK1 PRPF4 11418604 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CLK1 SRSF6 12549978 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CLK1 PPIG 14525934 25348397 8973360 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
CLK1 GOLM1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CLK1 MBP 14525934 25348397 8798720 N/A experimental interaction detection,in vitro ComPPI,HPRD
CLK1 BCLAF1 25348397 N/A physical interaction ComPPI
CLK1 SRSF3 25348397 N/A physical interaction ComPPI
CLK1 SAFB 25348397 N/A physical interaction ComPPI
CLK1 LUC7L3 12565863 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CLK1 SRPK2 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
CLK1 SRPK1 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
CLK1 PRMT5 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CLK1 PDE9A 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CLK1 TRA2A 25348397 N/A physical interaction ComPPI
CLK1 PRPF4B 25348397 N/A physical interaction ComPPI
CLK1 ABCA13 25348397 N/A physical interaction ComPPI
CLK1 ACOX2 25348397 N/A physical interaction ComPPI
CLK1 ANKFY1 25348397 N/A physical interaction ComPPI
CLK1 ARPC4 25348397 N/A physical interaction ComPPI
CLK1 ASL 25348397 N/A physical interaction ComPPI
CLK1 ASXL3 25348397 N/A physical interaction ComPPI
CLK1 ATP10A 25348397 N/A physical interaction ComPPI
CLK1 ATP4A 25348397 N/A physical interaction ComPPI
CLK1 C1ORF94 25348397 N/A physical interaction ComPPI
CLK1 CFAP20DC 25348397 N/A physical interaction ComPPI
CLK1 ELP6 25348397 N/A physical interaction ComPPI
CLK1 MTCL1 25348397 N/A physical interaction ComPPI
CLK1 CDH23 25348397 N/A physical interaction ComPPI
CLK1 CDK12 25348397 N/A physical interaction ComPPI
CLK1 CELSR3 25348397 N/A physical interaction ComPPI
CLK1 CENPE 25348397 N/A physical interaction ComPPI
CLK1 CEP95 25348397 N/A physical interaction ComPPI
CLK1 CKAP5 25348397 N/A physical interaction ComPPI
CLK1 CLASRP 25348397 N/A physical interaction ComPPI
CLK1 COCH 25348397 N/A physical interaction ComPPI
CLK1 CRNKL1 25348397 N/A physical interaction ComPPI
CLK1 CTNND2 25348397 N/A physical interaction ComPPI
CLK1 CWC27 25348397 N/A physical interaction ComPPI
CLK1 CYP46A1 25348397 N/A physical interaction ComPPI
CLK1 DBR1 25348397 N/A physical interaction ComPPI
CLK1 DENND4A 25348397 N/A physical interaction ComPPI
CLK1 DNAJC13 25348397 N/A physical interaction ComPPI
CLK1 DPYD 25348397 N/A physical interaction ComPPI
CLK1 DSC2 25348397 N/A physical interaction ComPPI
CLK1 ECE1 25348397 N/A physical interaction ComPPI
CLK1 MICU3 25348397 N/A physical interaction ComPPI
CLK1 ERFE 25348397 N/A physical interaction ComPPI
CLK1 FHIP2B 25348397 N/A physical interaction ComPPI
CLK1 FAT1 25348397 N/A physical interaction ComPPI
CLK1 FBF1 25348397 N/A physical interaction ComPPI
CLK1 GEMIN5 25348397 N/A physical interaction ComPPI
CLK1 GRM6 25348397 N/A physical interaction ComPPI
CLK1 GSDMB 25348397 N/A physical interaction ComPPI
CLK1 HADH 25348397 N/A physical interaction ComPPI
CLK1 H2BC12 25348397 N/A physical interaction ComPPI
CLK1 H2BS1 25348397 N/A physical interaction ComPPI
CLK1 HIVEP1 25348397 N/A physical interaction ComPPI
CLK1 HNMT 25348397 N/A physical interaction ComPPI
CLK1 HNRNPA0 25348397 N/A physical interaction ComPPI
CLK1 HNRNPA1 25348397 N/A physical interaction ComPPI
CLK1 HNRNPA3 25348397 N/A physical interaction ComPPI
CLK1 PLAAT5 25348397 N/A physical interaction ComPPI
CLK1 HTATSF1 25348397 N/A physical interaction ComPPI
CLK1 IP6K1 25348397 N/A physical interaction ComPPI
CLK1 ITGA5 25348397 N/A physical interaction ComPPI
CLK1 KATNA1 25348397 N/A physical interaction ComPPI
CLK1 ICE1 25348397 N/A physical interaction ComPPI
CLK1 KIF14 25348397 N/A physical interaction ComPPI
CLK1 KIF23 25348397 N/A physical interaction ComPPI
CLK1 KRT8 25348397 N/A physical interaction ComPPI
CLK1 LINS1 25348397 N/A physical interaction ComPPI
CLK1 MAP7 25348397 N/A physical interaction ComPPI
CLK1 MFSD10 25348397 N/A physical interaction ComPPI
CLK1 MKRN2 25348397 N/A physical interaction ComPPI
CLK1 MAP3K21 25348397 N/A physical interaction ComPPI
CLK1 MTBP 25348397 N/A physical interaction ComPPI
CLK1 MYOM1 25348397 N/A physical interaction ComPPI
CLK1 NCL 25348397 N/A physical interaction ComPPI
CLK1 NF1 25348397 N/A physical interaction ComPPI
CLK1 NUP153 25348397 N/A physical interaction ComPPI
CLK1 PATZ1 25348397 N/A physical interaction ComPPI
CLK1 PHF3 25348397 N/A physical interaction ComPPI
CLK1 PHLDB2 25348397 N/A physical interaction ComPPI
CLK1 PIP4K2B 25348397 N/A physical interaction ComPPI
CLK1 PKD1L1 25348397 N/A physical interaction ComPPI
CLK1 PLXDC2 25348397 N/A physical interaction ComPPI
CLK1 PPFIBP2 25348397 N/A physical interaction ComPPI
CLK1 PPHLN1 25348397 N/A physical interaction ComPPI
CLK1 PRDX5 25348397 N/A physical interaction ComPPI
CLK1 RAPH1 25348397 N/A physical interaction ComPPI
CLK1 RASL12 25348397 N/A physical interaction ComPPI
CLK1 RBM15 25348397 N/A physical interaction ComPPI
CLK1 RBMX 25348397 N/A physical interaction ComPPI
CLK1 REV1 25348397 N/A physical interaction ComPPI
CLK1 RLF 25348397 N/A physical interaction ComPPI
CLK1 RPL5 25348397 N/A physical interaction ComPPI
CLK1 RPS4Y1 25348397 N/A physical interaction ComPPI
CLK1 RPUSD3 25348397 N/A physical interaction ComPPI
CLK1 SAMD9L 25348397 N/A physical interaction ComPPI
CLK1 SCARA3 25348397 N/A physical interaction ComPPI
CLK1 SFMBT2 25348397 N/A physical interaction ComPPI
CLK1 SRSF5 25348397 N/A physical interaction ComPPI
CLK1 SRSF7 25348397 N/A physical interaction ComPPI
CLK1 SHROOM1 25348397 N/A physical interaction ComPPI
CLK1 SLC35D3 25348397 N/A physical interaction ComPPI
CLK1 SLFN5 25348397 N/A physical interaction ComPPI
CLK1 SPEN 25348397 N/A physical interaction ComPPI
CLK1 SPTBN4 25348397 N/A physical interaction ComPPI
CLK1 SRRM2 25348397 N/A physical interaction ComPPI
CLK1 SSBP3 25348397 N/A physical interaction ComPPI
CLK1 STK31 25348397 N/A physical interaction ComPPI
CLK1 SVOP 25348397 N/A physical interaction ComPPI
CLK1 TEX11 25348397 N/A physical interaction ComPPI
CLK1 THRAP3 25348397 N/A physical interaction ComPPI
CLK1 THY1 25348397 N/A physical interaction ComPPI
CLK1 TJP2 25348397 N/A physical interaction ComPPI
CLK1 TLN2 25348397 N/A physical interaction ComPPI
CLK1 TMPO 25348397 N/A physical interaction ComPPI
CLK1 TMPO 25348397 N/A physical interaction ComPPI
CLK1 TMPRSS2 25348397 N/A physical interaction ComPPI
CLK1 TNIP2 25348397 N/A physical interaction ComPPI
CLK1 TRA2B 25348397 N/A physical interaction ComPPI
CLK1 UNC13B 25348397 N/A physical interaction ComPPI
CLK1 VWA7 25348397 N/A physical interaction ComPPI
CLK1 CFAP251 25348397 N/A physical interaction ComPPI
CLK1 YTHDC1 25348397 N/A physical interaction ComPPI
CLK1 ZC3H13 25348397 N/A physical interaction ComPPI
CLK1 ZC3H18 25348397 N/A physical interaction ComPPI
CLK1 ZMYND10 25348397 N/A physical interaction ComPPI
CLK1 ZNF148 25348397 N/A physical interaction ComPPI
CLK1 KLC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CLK1 COA8 25348397 N/A physical interaction ComPPI
CLK1 PSEN2 24234451 25348397 26496610 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CLK1 SYMPK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CLK1 AKAP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CLK1 PPP4R3A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CLK1 DOCK9 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
CLK1 MFHAS1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
TP53RK CLK1 25348397 N/A physical interaction ComPPI
SERPINI2 CLK1 25348397 N/A physical interaction ComPPI
SRRM1 CLK1 25348397 N/A physical interaction ComPPI
PRPF38A CLK1 25348397 N/A physical interaction ComPPI
CLK1 CLK1 12549978 14525934 N/A experimental interaction detection HPRD
CLK1 PTPN1 10480872 11106648 11579209 18691976 27898060 8491187 8999839 stimulant N/A OmniPath
CLK1 ABL1 18794806 27898060 inhibition N/A OmniPath
ISG15 CLK1 16009940 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009BD860 CLK1 27087310 direct interaction,inhibition N/A NPInter

Visualization










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