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GENE：CTNND1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CTNND1
FullNmae catenin delta 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2515
EnsembleID ENSG00000198561
Uniprot O60716

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CTNND1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CTNND1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CTNND1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CTNND1 GO:0005102,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0005886,GO:0005911,GO:0005912,GO:0005915,GO:0007043,GO:0008013,GO:0009986,GO:0016055,GO:0016342,GO:0030027,GO:0030426,GO:0030496,GO:0043197,GO:0044331,GO:0045296,GO:0045296,GO:0045296,GO:0045296,GO:0050821,GO:0051220,GO:0070062,GO:0090090,GO:0098609,GO:0098685,GO:0098686,GO:0098831,GO:0098978,GO:0099072,GO:0099072,GO:0099072,GO:0099092,GO:1990782

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CTNND1 hsa:1500 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
CTNND1 hsa:1500 path:hsa04520 Adherens junction - Homo sapiens (human)
CTNND1 hsa:1500 path:hsa04670 Leukocyte transendothelial migration - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PIP5K1C CTNND1 17261850 23180781 physical association anti tag coimmunoprecipitation InnateDB
CDH1 CTNND1 17261850 23180781 8660921 physical association anti tag coimmunoprecipitation InnateDB
CDH3 CTNND1 23180781 8660921 physical association anti tag coimmunoprecipitation InnateDB
CDH2 CTNND1 23180781 8660921 physical association anti tag coimmunoprecipitation InnateDB
CDH24 CTNND1 12734196 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK3 CTNND1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP CTNND1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
AR CTNND1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 CTNND1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CTNND1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 CTNND1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 CTNND1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 CTNND1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 CTNND1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CTNND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CTNND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CTNND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CTNND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CTNND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CTNND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CTNND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CTNND1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 CTNND1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065D58 CTNND1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003D5391 CTNND1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D CTNND1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC CTNND1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 CTNND1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000008A99 CTNND1 22942087 25416803 mrna cleavage,inhibition array technology TarBase
URS00004F4657 CTNND1 22942087 25416803 25470111 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000272A3D CTNND1 25416803 25634213 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000081E1F CTNND1 22100165 25416803 26992637 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS000049FAE8 CTNND1 22012620 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000308E4D CTNND1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003804D8 CTNND1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 CTNND1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 CTNND1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5659 CTNND1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE CTNND1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA CTNND1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 CTNND1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075A760 CTNND1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002152A8 CTNND1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000137EDE CTNND1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000019907A CTNND1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000330617 CTNND1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001B341F CTNND1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000035AC91 CTNND1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000053B1E8 CTNND1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000BD1DE CTNND1 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075ABF4 CTNND1 22012620 23592263 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000157FBE CTNND1 22012620 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002FB065 CTNND1 22012620 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000519450 CTNND1 22012620 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000076E54 CTNND1 22012620 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000122ED0 CTNND1 25416803 26263183 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00001067D1 CTNND1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK1E CTNND1 22135298 phosphorylation N/A PhosphoSite
PRKCE CTNND1 22135298 phosphorylation N/A PhosphoSite
PRKCA CTNND1 22135298 phosphorylation N/A PhosphoSite
ZBTB33 CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 ZBTB33 25361965 interaction type N/A PTMCode2
FYN CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 FYN 25361965 interaction type N/A PTMCode2
FER CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 FER 25361965 interaction type N/A PTMCode2
CTNNA1 CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 CTNNA1 25361965 interaction type N/A PTMCode2
CTNND1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 PTPRJ 25361965 interaction type N/A PTMCode2
PTPRJ CTNND1 25361965 interaction type N/A PTMCode2
SRC CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 SRC 25361965 interaction type N/A PTMCode2
CTTN CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 CTTN 25361965 interaction type N/A PTMCode2
EGFR CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 EGFR 25361965 interaction type N/A PTMCode2
CDH1 CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 CDH1 25361965 interaction type N/A PTMCode2
CDH2 CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 CDH2 25361965 interaction type N/A PTMCode2
CDH24 CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 CDH24 25361965 interaction type N/A PTMCode2
COL17A1 CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 COL17A1 25361965 interaction type N/A PTMCode2
PLEKHA7 CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 PLEKHA7 25361965 interaction type N/A PTMCode2
JUP CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 JUP 25361965 interaction type N/A PTMCode2
PTPRM CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 PTPRM 25361965 interaction type N/A PTMCode2
CDH5 CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 CDH5 25361965 interaction type N/A PTMCode2
CDH3 CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 CDH3 25361965 interaction type N/A PTMCode2
YES1 CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 YES1 25361965 interaction type N/A PTMCode2
CTNNB1 CTNND1 25361965 interaction type N/A PTMCode2
CTNND1 CTNNB1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC5L CTNND1 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
YES1 CTNND1 25348397 N/A physical interaction ComPPI
ACTG1 CTNND1 25348397 N/A physical interaction ComPPI
VCP CTNND1 25348397 N/A physical interaction ComPPI
FOXB1 CTNND1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
YWHAG CTNND1 14525934 15324660 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
BMI1 CTNND1 25348397 N/A physical interaction ComPPI
PTPN6 CTNND1 10835420 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
KEAP1 CTNND1 25348397 N/A physical interaction ComPPI
MCM2 CTNND1 25348397 N/A physical interaction ComPPI
KCTD6 CTNND1 25348397 N/A two hybrid,physical interaction,two hybrid prey pooling approach ComPPI
CTNND1 PTPRM 10753936 14525934 15588985 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CTNND1 FER 12640114 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CTNND1 ZBTB33 10207085 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,in vivo ComPPI,IntAct
CTNND1 CDH5 11855855 14525934 25348397 9378757 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CTNND1 ERBIN 25348397 N/A physical interaction,in vitro,in vivo ComPPI
CTNND1 CDH24 12734196 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CTNND1 COL17A1 10321838 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
CTNND1 CDH3 14525934 25348397 8660921 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CTNND1 EGFR 14525934 14996911 15657067 24189400 24234451 24658140 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,ubiquitin reconstruction,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CTNND1 GSK3B 12885254 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CTNND1 SRC 11382764 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CTNND1 ACTA1 11969288 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
CTNND1 CDH1 24234451 24424122 25348397 physical association two hybrid,x-ray crystallography,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,IntAct
CTNND1 PSEN1 11226248 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CTNND1 MTNR1B 14525934 17215244 24234451 25348397 26514267 association experimental interaction detection,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
CTNND1 CTTN 12835311 14525934 17576929 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
CTNND1 CTNNB1 25348397 N/A physical interaction ComPPI
CTNND1 CTNNA1 25348397 N/A physical interaction ComPPI
CTNND1 CDH2 21357690 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CTNND1 FYN 25348397 N/A physical interaction ComPPI
CTNND1 LCK 25348397 N/A physical interaction ComPPI
CTNND1 PTPRJ 12370829 12475979 14525934 24234451 25348397 dephosphorylation reaction,colocalization,physical association coimmunoprecipitation,experimental interaction detection,fluorescence technology,pull down,physical interaction,biochemical ComPPI,HPRD,IntAct
CTNND1 MUC1 11181067 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
CTNND1 WDR48 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CTNND1 SQSTM1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CTNND1 SNCA 25348397 N/A physical interaction ComPPI
CTNND1 RIPK3 25348397 N/A physical interaction ComPPI
CTNND1 ARRB2 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CTNND1 CUL3 25348397 N/A physical interaction ComPPI
CTNND1 CSNK1E 25348397 N/A physical interaction ComPPI
CTNND1 APP 25348397 N/A physical interaction ComPPI
CTNND1 MYC 21150319 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CTNND1 ATP4A 25348397 N/A physical interaction ComPPI
CTNND1 AP2M1 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CTNND1 AURKA 25348397 N/A physical interaction ComPPI
CTNND1 NXF1 25348397 N/A physical interaction ComPPI
CTNND1 CCDC8 25348397 N/A physical interaction ComPPI
CTNND1 SUMO2 25348397 N/A physical interaction ComPPI
CTNND1 NTRK1 25348397 N/A physical interaction ComPPI
CTNND1 IFI16 25348397 N/A physical interaction ComPPI
CTNND1 CEP135 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CTNND1 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CTNND1 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CTNND1 XPO1 25348397 N/A physical interaction ComPPI
CTNND1 PPP4R1 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
CTNND1 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CTNND1 PLPP3 20123964 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,far western blotting,pull down,physical interaction,confocal microscopy ComPPI,IntAct
CTNND1 BTRC 25348397 N/A physical interaction ComPPI
CTNND1 CTDSPL 25348397 N/A physical interaction ComPPI
CTNND1 MTMR7 25348397 N/A physical interaction ComPPI
CTNND1 CDH8 25348397 N/A physical interaction ComPPI
CTNND1 CTNNA3 25348397 N/A physical interaction ComPPI
CTNND1 G3BP1 25348397 N/A physical interaction ComPPI
CTNND1 HNRNPL 25348397 N/A physical interaction ComPPI
CTNND1 PLEKHA7 19041755 24234451 25348397 28877994 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,confocal microscopy,proximity ligation assay ComPPI,IntAct
CTNND1 YAP1 21376238 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CTNND1 RET 21357690 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CTNND1 FRMD5 22846708 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,fluorescence microscopy ComPPI,IntAct
CTNND1 MCM7 23764002 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CTNND1 NANOS1 17047063 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation ComPPI,IntAct,OmniPath
CTNND1 TUBB3 24234451 25348397 27291054 association pull down ComPPI,IntAct
CTNND1 TUBA1A 24234451 25348397 27291054 association pull down ComPPI,IntAct
CTNND1 WRAP73 24234451 25348397 26545777 association anti tag coimmunoprecipitation ComPPI,IntAct
CTNND1 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
CTNND1 PABPC1 24234451 25348397 28877994 colocalization,association anti bait coimmunoprecipitation,confocal microscopy ComPPI,IntAct
CTNND1 AGO2 24234451 25348397 28877994 colocalization,association anti bait coimmunoprecipitation,confocal microscopy ComPPI,IntAct
CTNND1 TNRC6A 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
CTNND1 TARBP2 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
CTNND1 RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CTNND1 EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CTNND1 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CTNND1 TGOLN2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
JUP CTNND1 14525934 25348397 7876318 N/A experimental interaction detection,in vivo ComPPI,HPRD
SOX2 CTNND1 25348397 N/A physical interaction ComPPI
ATF2 CTNND1 22304920 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSCB CTNND1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
CTNND1 CTNND1 10225956 10931041 14525934 N/A experimental interaction detection HPRD
CTNND1 GRIK2 12151522 14525934 N/A experimental interaction detection HPRD
SOD1 CTNND1 24234451 30021884 physical association cross-linking study IntAct
L1TD1 CTNND1 24234451 25702638 association anti bait coimmunoprecipitation IntAct
SRC CTNND1 11382764 14996911 17016520 17389395 18669648 18707149 20068231 27898060 stimulant N/A OmniPath
PRKACA CTNND1 22798526 27898060 inhibition N/A OmniPath
PRKCA CTNND1 18158786 18950621 22798526 27898060 N/A N/A OmniPath
CTNND1 CDH1 10225956 10409703 10629228 10931041 11226248 12427869 12640114 12707304 14610055 17261850 19711372 19726720 20371349 21670201 22693575 22715382 22752307 22850631 23180380 24424122 27898060 7542250 7651399 7876318 8660921 9535896 stimulant N/A OmniPath
PRKCE CTNND1 15684660 21251911 23542175 27898060 inhibition N/A OmniPath
FYN CTNND1 12640114 12835311 17194753 27898060 inhibition,stimulant N/A OmniPath
EGFR CTNND1 14996911 17016520 17389395 20068231 24189400 24658140 24797263 25402006 27898060 9535896 inhibition N/A OmniPath
CSNK1E CTNND1 27898060 3133391 inhibition N/A OmniPath
PTPN6 CTNND1 10835420 27898060 stimulant N/A OmniPath
CTNND1 RAC1 22946057 27898060 stimulant N/A OmniPath
ABL1 CTNND1 11891774 20841568 27898060 stimulant N/A OmniPath
GSK3B CTNND1 12885254 18212344 19706605 20166139 27898060 N/A N/A OmniPath
CTNND1 CDH2 12604612 14610055 14625392 20371349 21357690 27898060 8660921 stimulant N/A OmniPath
IL15 CTNND1 21903422 27898060 N/A N/A OmniPath
CTNND1 VAV2 22946057 27898060 stimulant N/A OmniPath
CTNND1 CDH5 11855855 14610055 27898060 9378757 stimulant N/A OmniPath
CTNND1 CDH3 14610055 23180380 27898060 8660921 stimulant N/A OmniPath
PTPRJ CTNND1 12370829 12475979 27898060 stimulant N/A OmniPath
PTPRT CTNND1 16973135 27898060 N/A N/A OmniPath
PAK5 CTNND1 18220336 18669648 20564219 27898060 N/A N/A OmniPath
PTPRM CTNND1 10753936 15588985 27898060 stimulant N/A OmniPath

Visualization










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