Gene Information gene info

GENE:EFNA4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EFNA4
FullNmae ephrin A4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3224
EnsembleID ENSG00000243364
Uniprot P52798

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EFNA4 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EFNA4 GO:0005005,GO:0005515,GO:0005576,GO:0005886,GO:0005886,GO:0007267,GO:0007411,GO:0046875,GO:0046875,GO:0048013,GO:0098552

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EFNA4 hsa:1945 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
EFNA4 hsa:1945 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
EFNA4 hsa:1945 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
EFNA4 hsa:1945 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
EFNA4 hsa:1945 path:hsa04360 Axon guidance - Homo sapiens (human)
EFNA4 hsa:1945 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EFNA4 EPHA6 23331499 9576626 stimulation N/A SignaLink,SignaLink
EFNA4 EPHA4 23331499 9267020 stimulation N/A SignaLink
EFNA4 EPHA7 23331499 9576626 stimulation N/A SignaLink
EFNA4 EPHA8 23331499 9576626 stimulation N/A SignaLink
EFNA4 EPHA2 23331499 9576626 stimulation N/A SignaLink
EFNA4 EPHA3 23331499 9195962 9576626 stimulation N/A SignaLink
EFNA4 EPHA5 23331499 9576626 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 EFNA4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 EFNA4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 EFNA4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 EFNA4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 EFNA4 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 EFNA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EFNA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 EFNA4 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
EPHA7 EFNA4 25361965 interaction type N/A PTMCode2
EFNA4 EPHA7 25361965 interaction type N/A PTMCode2
EPHA8 EFNA4 25361965 interaction type N/A PTMCode2
EFNA4 EPHA8 25361965 interaction type N/A PTMCode2
EPHA2 EFNA4 25361965 interaction type N/A PTMCode2
EFNA4 EPHA2 25361965 interaction type N/A PTMCode2
EPHA4 EFNA4 25361965 interaction type N/A PTMCode2
EFNA4 EPHA4 25361965 interaction type N/A PTMCode2
MAP2K4 EFNA4 25361965 interaction type N/A PTMCode2
EFNA4 MAP2K4 25361965 interaction type N/A PTMCode2
EPHA3 EFNA4 25361965 interaction type N/A PTMCode2
EFNA4 EPHA3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAP2K4 EFNA4 14525934 25348397 8755474 N/A experimental interaction detection,in vitro ComPPI,HPRD
EPHA2 EFNA4 10607706 14525934 25348397 8755474 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
EPHA8 EFNA4 10515610 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
EFNA4 EPHA5 10607706 14525934 25348397 8755474 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
EFNA4 EPHA4 10366629 14525934 19836338 24234451 25348397 N/A experimental interaction detection,surface plasmon resonance,physical interaction,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
EFNA4 EPHA7 14525934 22036564 24234451 25348397 8755474 N/A experimental interaction detection,in vitro,comigration in sds page ComPPI,HPRD,IntAct
EFNA4 EPHA6 25348397 N/A in vitro,in vivo ComPPI
EFNA4 EPHA3 25348397 N/A physical interaction ComPPI
EFNA4 MOV10 25348397 N/A physical interaction ComPPI
EFNA4 NXF1 25348397 N/A physical interaction ComPPI
EFNA4 TMEM147 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFNA4 EPHA2 10607706 15114347 27898060 8755474 stimulant N/A OmniPath
EFNA4 EPHA4 10366629 15114347 19836338 27898060 N/A N/A OmniPath
EFNA4 EPHA7 15114347 22036564 27898060 8755474 N/A N/A OmniPath
EPHA3 EFNA4 15114347 27898060 N/A N/A OmniPath
EFNA4 EPHA3 15114347 27898060 8755474 N/A N/A OmniPath
EFNA4 EPHA1 15114347 27898060 N/A N/A OmniPath
EFNA4 EPHA5 10607706 15114347 27898060 8755474 9330863 stimulant N/A OmniPath
EFNA4 EPHA8 10515610 15114347 27898060 N/A N/A OmniPath

Visualization