Gene Information gene info

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GENE：FZD1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FZD1
FullNmae frizzled class receptor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4038
EnsembleID ENSG00000157240
Uniprot Q9UP38

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FZD1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FZD1 GO:0001934,GO:0003149,GO:0003150,GO:0003151,GO:0004930,GO:0005102,GO:0005109,GO:0005515,GO:0005886,GO:0005886,GO:0005925,GO:0007186,GO:0007267,GO:0009410,GO:0009986,GO:0010976,GO:0017147,GO:0017147,GO:0017147,GO:0030165,GO:0030182,GO:0030514,GO:0035425,GO:0035567,GO:0036520,GO:0042813,GO:0042813,GO:0042813,GO:0042813,GO:0044338,GO:0044339,GO:0045446,GO:0045892,GO:0045893,GO:0051091,GO:0060022,GO:0060070,GO:0060070,GO:0060070,GO:0060070,GO:0090090,GO:0090179,GO:0099054,GO:1903377,GO:1904953,GO:1905606,GO:1990909

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FZD1 hsa:8321 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
FZD1 hsa:8321 path:hsa04310 Wnt signaling pathway - Homo sapiens (human)
FZD1 hsa:8321 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)
FZD1 hsa:8321 path:hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)
FZD1 hsa:8321 path:hsa04916 Melanogenesis - Homo sapiens (human)
FZD1 hsa:8321 path:hsa04934 Cushing syndrome - Homo sapiens (human)
FZD1 hsa:8321 path:hsa05010 Alzheimer disease - Homo sapiens (human)
FZD1 hsa:8321 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
FZD1 hsa:8321 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
FZD1 hsa:8321 path:hsa05200 Pathways in cancer - Homo sapiens (human)
FZD1 hsa:8321 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
FZD1 hsa:8321 path:hsa05217 Basal cell carcinoma - Homo sapiens (human)
FZD1 hsa:8321 path:hsa05224 Breast cancer - Homo sapiens (human)
FZD1 hsa:8321 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
FZD1 hsa:8321 path:hsa05226 Gastric cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FZD1 FZD1 22944199 26467481 bind,up-regulates activity N/A Signor
WNT3A FZD1 10557084 14627707 18988627 23331499 stimulation N/A SignaLink,SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 FZD1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 FZD1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 FZD1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 FZD1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 FZD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FZD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FZD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FZD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 FZD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FZD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FZD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 FZD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 FZD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 FZD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FZD1 20051274 23806799 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000029D9F1 FZD1 21282569 rna interference,inhibition array technology,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000029D9F1 FZD1 21282569 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 FZD1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 FZD1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 FZD1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000184017 FZD1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 FZD1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 FZD1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000001EB3 FZD1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000010F787 FZD1 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
WNT3A FZD1 25361965 interaction type N/A PTMCode2
FZD1 WNT3A 25361965 interaction type N/A PTMCode2
FZD1 CTNNB1 25361965 interaction type N/A PTMCode2
CTNNB1 FZD1 25361965 interaction type N/A PTMCode2
WNT5A FZD1 25361965 interaction type N/A PTMCode2
FZD1 WNT5A 25361965 interaction type N/A PTMCode2
WNT2 FZD1 25361965 interaction type N/A PTMCode2
FZD1 WNT2 25361965 interaction type N/A PTMCode2
WNT3 FZD1 25361965 interaction type N/A PTMCode2
FZD1 WNT3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GOLGA2 FZD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATP5F1B FZD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DERL2 FZD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DLG4 FZD1 12067714 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
WNT5A FZD1 10557084 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
FZD1 DLG2 12067714 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
FZD1 WNT3A 10557084 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
FZD1 WNT2 10557084 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
FZD1 WNT3 10557084 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FZD1 GSK3B 25348397 N/A physical interaction ComPPI
FZD1 RBM26 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FZD1 UPK1A 25348397 N/A physical interaction ComPPI
ARRB1 FZD1 11742073 27898060 stimulant N/A OmniPath
WNT1 FZD1 10557084 15578921 16936075 22944199 24032637 27898060 stimulant N/A OmniPath
WNT5A FZD1 10557084 24032637 27898060 stimulant N/A OmniPath
FZD1 DVL1 22944199 27898060 stimulant N/A OmniPath
WNT3A FZD1 10557084 10601008 21078818 27898060 stimulant N/A OmniPath
WNT10B FZD1 12055200 19008118 27898060 stimulant N/A OmniPath
WNT6 FZD1 12857724 27898060 8717036 stimulant N/A OmniPath
MACROD1 FZD1 12857724 27898060 stimulant N/A OmniPath
WNT7B FZD1 15923619 24032637 27898060 stimulant N/A OmniPath
MYOC FZD1 19188438 27898060 N/A N/A OmniPath

Visualization










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