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GENE：GFPT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GFPT1
FullNmae glutamine--fructose-6-phosphate transaminase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4241
EnsembleID ENSG00000198380
Uniprot Q06210

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GFPT1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GFPT1 GO:0004360,GO:0004360,GO:0005829,GO:0006002,GO:0006047,GO:0006048,GO:0006048,GO:0006048,GO:0006112,GO:0006487,GO:0006541,GO:0032922,GO:0070062,GO:0097367

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GFPT1 hsa:2673 path:hsa00250 Alanine, aspartate and glutamate metabolism - Homo sapiens (human)
GFPT1 hsa:2673 path:hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human)
GFPT1 hsa:2673 path:hsa01100 Metabolic pathways - Homo sapiens (human)
GFPT1 hsa:2673 path:hsa01250 Biosynthesis of nucleotide sugars - Homo sapiens (human)
GFPT1 hsa:2673 path:hsa04931 Insulin resistance - Homo sapiens (human)
GFPT1 hsa:2673 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 GFPT1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 GFPT1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GFPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GFPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GFPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GFPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GFPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GFPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GFPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 GFPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GFPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GFPT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000272039 GFPT1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000237AF9 GFPT1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EED18 GFPT1 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000027080C GFPT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000079D48 GFPT1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A GFPT1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 GFPT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000029D793 GFPT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB16 GFPT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000605E00 GFPT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 GFPT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000D6C3F GFPT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 GFPT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000009265 GFPT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000058863C GFPT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 GFPT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD GFPT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D GFPT1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075BEA7 GFPT1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000472A9B GFPT1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000345DEB GFPT1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004E008F GFPT1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 GFPT1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 GFPT1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000076E54 GFPT1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B GFPT1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007A060 GFPT1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 GFPT1 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 GFPT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA GFPT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000358C16 GFPT1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000101787 GFPT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004818BD GFPT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003E1A9 GFPT1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 GFPT1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 GFPT1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC GFPT1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000048D44E GFPT1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000086A4D GFPT1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000221168 GFPT1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003E226A GFPT1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00005CC20C GFPT1 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CAMK2A GFPT1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 GFPT1 22135298 phosphorylation N/A PhosphoSite
PRKACA GFPT1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
PRKAA2 GFPT1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LDHB GFPT1 25348397 N/A physical interaction ComPPI
ATP5F1B GFPT1 25348397 N/A physical interaction ComPPI
PPP2R1A GFPT1 25348397 N/A physical interaction ComPPI
MCM2 GFPT1 25348397 N/A physical interaction ComPPI
CRK GFPT1 25348397 N/A physical interaction ComPPI
PFDN4 GFPT1 25348397 N/A physical interaction ComPPI
H4C1 GFPT1 25348397 N/A physical interaction ComPPI
MAPK8 GFPT1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PRKCA GFPT1 10806197 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
JUN GFPT1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
ARHGAP1 GFPT1 25348397 N/A physical interaction ComPPI
OSBP GFPT1 25348397 N/A physical interaction ComPPI
RBX1 GFPT1 25348397 N/A physical interaction ComPPI
NTRK1 GFPT1 25348397 N/A physical interaction ComPPI
MYC GFPT1 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
LRP1 GFPT1 25348397 N/A physical interaction ComPPI
CAD GFPT1 25348397 N/A physical interaction ComPPI
CFTR GFPT1 25348397 N/A physical interaction ComPPI
XPO1 GFPT1 25348397 N/A physical interaction ComPPI
PSMC4 GFPT1 25348397 N/A physical interaction ComPPI
TTC1 GFPT1 25348397 N/A physical interaction ComPPI
PFDN5 GFPT1 25348397 N/A physical interaction ComPPI
PSMD2 GFPT1 25348397 N/A physical interaction ComPPI
SF1 GFPT1 25348397 N/A physical interaction ComPPI
PSMD4 GFPT1 25348397 N/A physical interaction ComPPI
RO60 GFPT1 25348397 N/A physical interaction ComPPI
UBA1 GFPT1 25348397 N/A physical interaction ComPPI
MARS1 GFPT1 25348397 N/A physical interaction ComPPI
IARS1 GFPT1 25348397 N/A physical interaction ComPPI
GARS1 GFPT1 25348397 N/A physical interaction ComPPI
NCBP1 GFPT1 25348397 N/A physical interaction ComPPI
ELAVL1 GFPT1 25348397 N/A physical interaction ComPPI
KPNA6 GFPT1 25348397 N/A physical interaction ComPPI
DCP2 GFPT1 25348397 N/A physical interaction ComPPI
KHSRP GFPT1 25348397 N/A physical interaction ComPPI
PRMT3 GFPT1 25348397 N/A physical interaction ComPPI
NMD3 GFPT1 25348397 N/A physical interaction ComPPI
PRKAB2 GFPT1 25348397 N/A physical interaction ComPPI
XPO7 GFPT1 25348397 N/A physical interaction ComPPI
SEC23A GFPT1 25348397 N/A physical interaction ComPPI
MCM7 GFPT1 23764002 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
DARS1 GFPT1 25348397 N/A physical interaction ComPPI
FASN GFPT1 25348397 N/A physical interaction ComPPI
SIRT6 GFPT1 25348397 N/A physical interaction ComPPI
RNF126 GFPT1 25348397 N/A physical interaction ComPPI
PSMC2 GFPT1 25348397 N/A physical interaction ComPPI
TTC27 GFPT1 25348397 N/A physical interaction ComPPI
CCT6A GFPT1 25348397 N/A physical interaction ComPPI
ACADM GFPT1 25348397 N/A physical interaction ComPPI
AHSA1 GFPT1 25348397 N/A physical interaction ComPPI
ASNS GFPT1 25348397 N/A physical interaction ComPPI
SIRT7 GFPT1 25348397 N/A physical interaction ComPPI
DNAAF5 GFPT1 25348397 N/A physical interaction ComPPI
TARS1 GFPT1 25348397 N/A physical interaction ComPPI
CCT8 GFPT1 25348397 N/A physical interaction ComPPI
GFPT1 CARS1 25348397 N/A physical interaction ComPPI
GFPT1 UNK 25348397 N/A physical interaction ComPPI
GFPT1 PSMD3 25348397 N/A physical interaction ComPPI
GFPT1 SETD3 25348397 N/A physical interaction ComPPI
GFPT1 POC5 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
GFPT1 TCTN1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
GFPT1 GFPT2 25348397 N/A physical interaction ComPPI
GFPT1 G3BP1 25348397 N/A physical interaction ComPPI
GFPT1 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSCB GFPT1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
PRKACA GFPT1 10806197 27898060 9836513 N/A N/A OmniPath
MAPK3 GFPT1 10806197 27898060 9836513 N/A N/A OmniPath
CAMK2A GFPT1 17941647 27898060 stimulant N/A OmniPath
PRKAA1 GFPT1 17941647 19170765 27898060 inhibition,stimulant N/A OmniPath

Visualization










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