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GENE：H2AX

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol H2AX
FullNmae H2A.X variant histone
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4739
EnsembleID ENSG00000188486
Uniprot P16104

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
H2AX parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
H2AX mitotic_cd 23519742 DNA damage and repair were measured using gammaH2AX foci, and mitotic catastrophe was determined by immunostaining. retulator signature
H2AX immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
H2AX ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
H2AX autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
H2AX GO:0000077,GO:0000724,GO:0000781,GO:0000786,GO:0000794,GO:0001673,GO:0001741,GO:0003677,GO:0003677,GO:0003684,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005657,GO:0005813,GO:0006302,GO:0006334,GO:0006974,GO:0006974,GO:0006974,GO:0007283,GO:0010212,GO:0016607,GO:0019899,GO:0021987,GO:0030527,GO:0035861,GO:0042393,GO:0045739,GO:0046982,GO:0051321,GO:0070062,GO:0071480,GO:0090398,GO:0090734

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
H2AX hsa:3014 path:hsa03082 ATP-dependent chromatin remodeling - Homo sapiens (human)
H2AX hsa:3014 path:hsa04217 Necroptosis - Homo sapiens (human)
H2AX hsa:3014 path:hsa04613 Neutrophil extracellular trap formation - Homo sapiens (human)
H2AX hsa:3014 path:hsa05034 Alcoholism - Homo sapiens (human)
H2AX hsa:3014 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 H2AX 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC H2AX 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 H2AX 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 H2AX 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CTCF H2AX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 H2AX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR H2AX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GLI1 H2AX 21860067 trascriptional regulation,stimulation inferred by curator TFlink
GLI2 H2AX 21860067 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005FDE70 H2AX 19377482 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr miRSponge
URS00005FDE70 H2AX 19377482 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr TarBase
URS00005651EE H2AX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD H2AX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000A07C1 H2AX 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000419B5A H2AX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000033B548 H2AX 20371350 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004929F1 H2AX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002373FD H2AX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000077DDE H2AX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C403E H2AX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000035D2F9 H2AX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000913AC H2AX 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000054A671 H2AX 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004C5774 H2AX 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD1DE H2AX 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075A608 H2AX 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 H2AX 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 H2AX 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 H2AX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 H2AX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002F72ED H2AX 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000157FBE H2AX 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 H2AX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F H2AX 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS0000078918 H2AX 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000013DD8 H2AX 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075E538 H2AX 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKDC H2AX 22135298 phosphorylation N/A PhosphoSite
BAZ1B H2AX 22135298 phosphorylation N/A PhosphoSite
STK4 H2AX 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
HNRNPC H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX21 H2AX 25348397 N/A physical interaction ComPPI
TXNDC12 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LDHB H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NPM1 H2AX 25348397 N/A physical interaction ComPPI
RPS28 H2AX 25348397 N/A physical interaction ComPPI
CFL1 H2AX 20000738 24234451 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
BTF3 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HAT1 H2AX 20224553 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP1 H2AX 12447390 12607005 12697768 14525934 17024177 18001824 18001825 20075863 21317870 24234451 25348397 colocalization,physical association experimental interaction detection,pull down,physical interaction,fluorescence microscopy,imaging technique,in vivo,confocal microscopy ComPPI,HPRD,IntAct
TRAF6 H2AX 25348397 N/A physical interaction ComPPI
LMNA H2AX 20000738 23658700 24234451 25348397 27898060 association,physical association anti tag coimmunoprecipitation,physical interaction,proximity ligation assay ComPPI,IntAct,OmniPath
MCM5 H2AX 25348397 N/A physical interaction ComPPI
ACTB H2AX 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CALM1 H2AX 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
RPS15 H2AX 25348397 N/A physical interaction ComPPI
BMI1 H2AX 21383063 21676867 25348397 27898060 N/A physical interaction ComPPI,OmniPath
H2BC4 H2AX 25348397 N/A physical interaction ComPPI
MCM6 H2AX 25348397 N/A physical interaction ComPPI
MCM2 H2AX 25348397 N/A physical interaction ComPPI
SNAI1 H2AX 24234451 25348397 25640309 colocalization fluorescence microscopy ComPPI,IntAct
SLC25A6 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTGES2 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PEF1 H2AX 20000738 24234451 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
ERO1A H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CETN2 H2AX 25348397 N/A physical interaction ComPPI
ANXA4 H2AX 25348397 N/A physical interaction ComPPI
H4C1 H2AX 20000738 20224553 24234451 25348397 30021884 association,physical association anti tag coimmunoprecipitation,cross-linking study,physical interaction ComPPI,IntAct
RNF115 H2AX 25348397 N/A physical interaction ComPPI
PAK1 H2AX 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAPK8 H2AX 19234442 24234451 25348397 physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
SUMF2 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FGF3 H2AX 25348397 N/A physical interaction ComPPI
ATR H2AX 25348397 N/A physical interaction ComPPI
PRKDC H2AX 20085707 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NACA H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DHX9 H2AX 25348397 N/A physical interaction ComPPI
HIF1A H2AX 25348397 N/A physical interaction ComPPI
NONO H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KAT2B H2AX 20224553 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NHEJ1 H2AX 18064046 24234451 25348397 27898060 colocalization fluorescence microscopy ComPPI,IntAct,OmniPath
PAXIP1 H2AX 22064073 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CLU H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAB H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAZ H2AX 20000738 20618440 24234451 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,confocal microscopy,tandem affinity purification ComPPI,IntAct
CTSD H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDIA6 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBB H2AX 18001824 24234451 25348397 colocalization anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
UBC H2AX 25348397 N/A anti tag coimmunoprecipitation,physical interaction,physical interaction ComPPI
RPS27A H2AX 25348397 N/A anti tag coimmunoprecipitation,physical interaction,physical interaction ComPPI
UBA52 H2AX 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
HSP90AA1 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
P3H1 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ENO1 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAPPA H2AX 25348397 N/A physical interaction ComPPI
RUVBL1 H2AX 25348397 N/A physical interaction ComPPI
YBX1 H2AX 25348397 N/A physical interaction ComPPI
PARP1 H2AX 16377563 20000738 20085707 24234451 25348397 27728808 colocalization,association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,confocal microscopy ComPPI,IntAct
RPS3A H2AX 25348397 N/A physical interaction ComPPI
XRCC1 H2AX 19851285 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
WRN H2AX 14525934 15733840 20802463 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct
XRCC5 H2AX 20085707 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PARP2 H2AX 25348397 N/A physical interaction ComPPI
SSBP1 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NAXE H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CALR H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
APBB1 H2AX 19234442 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
P4HB H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA5 H2AX 25348397 N/A physical interaction ComPPI
SMARCA4 H2AX 20224553 24234451 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
HSPA1A H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA1B H2AX 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
POLH H2AX 24234451 24485656 25348397 colocalization fluorescence microscopy ComPPI,IntAct
HSP90B1 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRDX4 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDIA4 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP1CA H2AX 12926989 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
LILRB2 H2AX 16455647 24234451 25348397 physical association surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
CSNK2A1 H2AX 25348397 N/A physical interaction ComPPI
XRCC6 H2AX 25348397 N/A physical interaction ComPPI
EEF1A1 H2AX 25348397 N/A physical interaction ComPPI
RPS6KA3 H2AX 25348397 N/A physical interaction ComPPI
PPP2CA H2AX 18758438 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PABPC1 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PKM H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAZ1A H2AX 25348397 N/A physical interaction ComPPI
RAD51 H2AX 21317870 24234451 25348397 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct
FANCD2 H2AX 19609304 24234451 25348397 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct
BRCA2 H2AX 25348397 N/A physical interaction ComPPI
BLM H2AX 25348397 N/A physical interaction ComPPI
ATM H2AX 11571274 11893489 14525934 16858402 22451927 24234451 25348397 9488723 colocalization,association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique,in vivo ComPPI,HPRD,IntAct
H2BC21 H2AX 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
YWHAQ H2AX 25348397 N/A physical interaction ComPPI
QARS1 H2AX 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBBP8 H2AX 22773103 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRAP1 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARRB1 H2AX 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF8 H2AX 18001824 18001825 24234451 25348397 colocalization physical interaction,fluorescence microscopy,confocal microscopy ComPPI,IntAct
RPS6 H2AX 25348397 N/A physical interaction ComPPI
HUWE1 H2AX 25348397 N/A physical interaction ComPPI
TOPORS H2AX 25348397 N/A physical interaction ComPPI
RPS18 H2AX 25348397 N/A physical interaction ComPPI
RNF168 H2AX 19203578 24234451 25348397 colocalization physical interaction,confocal microscopy ComPPI,IntAct
RPLP2 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPA2B1 H2AX 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
NEDD8 H2AX 18274552 24234451 25348397 association tandem affinity purification ComPPI,IntAct
ARRB2 H2AX 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TPT1 H2AX 22451927 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MACROD1 H2AX 25348397 N/A physical interaction ComPPI
CBX5 H2AX 25348397 N/A physical interaction ComPPI
SYNCRIP H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H3-4 H2AX 20224553 24234451 25348397 30021884 association,physical association anti tag coimmunoprecipitation,cross-linking study ComPPI,IntAct
EGFR H2AX 25348397 N/A physical interaction ComPPI
YWHAE H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ANXA2 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCT5 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NGFR H2AX 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
H3C15 H2AX 25348397 N/A physical interaction ComPPI
RNF2 H2AX 25348397 N/A physical interaction ComPPI
YBX3 H2AX 25348397 N/A physical interaction ComPPI
MIER1 H2AX 25348397 N/A physical interaction ComPPI
SUPT16H H2AX 25348397 N/A physical interaction ComPPI
TRIM28 H2AX 21317870 24234451 25348397 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct
XPC H2AX 25348397 N/A physical interaction ComPPI
POLR2A H2AX 25348397 N/A physical interaction ComPPI
BRD1 H2AX 25348397 N/A physical interaction ComPPI
KAT2A H2AX 20224553 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA9 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VRK1 H2AX 24234451 25348397 25923214 27898060 phosphorylation reaction,physical association anti bait coimmunoprecipitation,protein kinase assay ComPPI,IntAct,OmniPath
STK11 H2AX 24234451 25348397 25852190 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAF1C H2AX 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
STK4 H2AX 25348397 N/A physical interaction ComPPI
MDC1 H2AX 12607005 14519663 14525934 16377563 18001824 18001825 18583988 19234442 20159462 21293379 24234451 25348397 colocalization,association,physical association anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,fluorescence polarization spectroscopy,isothermal titration calorimetry,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,fluorescence microscopy,imaging technique,in vivo,enzymatic footprinting,confocal microscopy,surface plasmon resonance array ComPPI,HPRD,IntAct
BANP H2AX 25348397 N/A physical interaction ComPPI
MSN H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LIG3 H2AX 25348397 N/A physical interaction ComPPI
GLB1 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRDX6 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HEXA H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BAZ1B H2AX 25348397 N/A phosphorylation reaction,protein kinase assay ComPPI
ATRX H2AX 25348397 N/A physical interaction ComPPI
USP11 H2AX 25348397 N/A physical interaction ComPPI
SSB H2AX 25348397 N/A physical interaction ComPPI
H3C1 H2AX 25348397 N/A physical interaction ComPPI
UPF1 H2AX 25348397 N/A physical interaction ComPPI
SUPT5H H2AX 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PDCD6 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PBK H2AX 25348397 N/A physical interaction ComPPI
PGK1 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPIA H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FOXA1 H2AX 25348397 N/A physical interaction ComPPI
BARD1 H2AX 25348397 N/A physical interaction ComPPI
AIRE H2AX 20085707 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPR H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HLA-G H2AX 16455647 24234451 25348397 physical association surface plasmon resonance,x-ray crystallography ComPPI,IntAct
EIF2S2 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MASP1 H2AX 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LILRB1 H2AX 16455647 24234451 25348397 physical association surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
SSRP1 H2AX 25348397 N/A physical interaction ComPPI
BIRC5 H2AX 25348397 N/A physical interaction ComPPI
ELAVL1 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PCBP2 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HMGA2 H2AX 24234451 25348397 26045162 association anti bait coimmunoprecipitation ComPPI,IntAct
PTPA H2AX 25348397 N/A physical interaction ComPPI
H2AX MRE11 12419185 14525934 16377563 18583988 19234442 22157895 24234451 25348397 colocalization,association,physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct
H2AX BRCA1 12419185 14525934 18001824 18001825 22193777 24234451 25348397 colocalization,physical association coimmunoprecipitation,cosedimentation through density gradient,experimental interaction detection,physical interaction,fluorescence microscopy,in vivo,confocal microscopy ComPPI,HPRD,IntAct
H2AX NBN 11110662 12419185 14525934 15733840 16377563 18001824 18001825 18583988 22157895 22565321 24234451 25348397 colocalization,association,physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,in vitro,in vivo,confocal microscopy ComPPI,HPRD,IntAct
H2AX ALG9 14519663 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
H2AX RAD50 16377563 18583988 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
H2AX PPM1D 20118229 24234451 25348397 dephosphorylation reaction,physical association anti tag coimmunoprecipitation,physical interaction,phosphatase assay ComPPI,IntAct
H2AX EYA1 19234442 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX EYA3 19234442 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX DMAP1 25348397 N/A physical interaction ComPPI
H2AX CHD1L 25348397 N/A anti tag coimmunoprecipitation,physical interaction,physical interaction ComPPI
H2AX SMARCA2 20224553 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX EIF3L 25348397 N/A physical interaction ComPPI
H2AX DHX30 25348397 N/A physical interaction ComPPI
H2AX H2BC14 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
H2AX H2BC11 25348397 N/A physical interaction ComPPI
H2AX PTCD3 25348397 N/A physical interaction ComPPI
H2AX TP53 25348397 N/A physical interaction ComPPI
H2AX TSSK6 25348397 N/A physical interaction ComPPI
H2AX KAT5 20224553 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX EEF1A1P5 25348397 N/A physical interaction ComPPI
H2AX PPM1G 25348397 N/A physical interaction ComPPI
H2AX FOXO3 25348397 N/A physical interaction ComPPI
H2AX RAD17 25348397 N/A physical interaction ComPPI
H2AX H2AC20 25348397 N/A physical interaction ComPPI
H2AX KAT8 20224553 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX TP53I3 20023697 25348397 27898060 N/A physical interaction ComPPI,OmniPath
H2AX ANXA5 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX TMX1 25348397 N/A physical interaction ComPPI
H2AX TOR1B 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX HSP90AA2P 25348397 N/A physical interaction ComPPI
H2AX HSPA1L 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX PLOD1 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX SOD2 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX AIFM1 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX TOR1A 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX HYOU1 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX EIF4A1 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX RPS10 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX CPS1 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX ANXA2P2 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX ANXA6 25348397 N/A physical interaction ComPPI
H2AX MATR3 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX ALDOA 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX POFUT1 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX HNRNPD 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX HNRNPDL 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX HNRNPH3 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX HNRNPAB 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX MSI2 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX ALYREF 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX HNRNPA1 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX ERP29 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX VAT1 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX NACA 25348397 N/A physical interaction ComPPI
H2AX NACA4P 25348397 N/A physical interaction ComPPI
H2AX FKBP10 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX P4HA2 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX RPN2 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX HSD17B10 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX TKT 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX GANAB 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX CMBL 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX PRKCSH 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX LGALS3BP 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX ABHD10 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX CFAP45 25348397 N/A physical interaction ComPPI
H2AX RMDN1 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX PRDX3 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX HIBCH 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX OTUB1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
H2AX A2M 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
H2AX TAF5L 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
H2AX TIAM2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
H2AX COPG1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
H2AX CBX2 25348397 N/A physical interaction ComPPI
H2AX MCPH1 25348397 N/A physical interaction ComPPI
H2AX SIRT7 25348397 N/A physical interaction ComPPI
H2AX PML 25348397 N/A physical interaction ComPPI
H2AX TERF2 21044950 21824286 22157895 24234451 25348397 colocalization,physical association pull down,physical interaction,fluorescence microscopy,bimolecular fluorescence complementation ComPPI,IntAct
H2AX CENPA 25348397 N/A physical interaction ComPPI
H2AX ESR1 21182205 24234451 25348397 association cosedimentation through density gradient,physical interaction ComPPI,IntAct
H2AX NCL 25348397 N/A physical interaction ComPPI
H2AX USP17L2 24704006 25348397 27898060 N/A physical interaction ComPPI,OmniPath
H2AX SURF2 25348397 N/A physical interaction ComPPI
H2AX RPS2 25348397 N/A physical interaction ComPPI
H2AX PAIP1 25348397 N/A physical interaction ComPPI
H2AX C5ORF64 25348397 N/A physical interaction ComPPI
H2AX WRAP53 25348397 N/A physical interaction ComPPI
H2AX ENY2 25348397 N/A physical interaction ComPPI
H2AX MLLT1 25348397 N/A physical interaction ComPPI
H2AX DIS3L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H2AX H2BC17 25348397 N/A physical interaction ComPPI
H2AX H2BC5 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
H2AX GON4L 25348397 N/A physical interaction ComPPI
H2AX TONSL 25348397 N/A physical interaction ComPPI
H2AX H1-2 25348397 N/A physical interaction ComPPI
H2AX PHF14 25348397 N/A physical interaction ComPPI
H2AX MMS22L 25348397 N/A physical interaction ComPPI
H2AX H1-6 25348397 N/A physical interaction ComPPI
H2AX IPO9 25348397 N/A physical interaction ComPPI
H2AX CRAMP1 25348397 N/A physical interaction ComPPI
H2AX YBX2 25348397 N/A physical interaction ComPPI
H2AX SS18L2 25348397 N/A physical interaction ComPPI
H2AX H2AC21 25348397 N/A physical interaction ComPPI
H2AX MIER3 25348397 N/A physical interaction ComPPI
H2AX MAGEB10 25348397 N/A physical interaction ComPPI
H2AX C16ORF87 25348397 N/A physical interaction ComPPI
H2AX ZC3HAV1 25348397 N/A physical interaction ComPPI
H2AX NPAT 25348397 N/A physical interaction ComPPI
H2AX GAN 25348397 N/A physical interaction ComPPI
H2AX MCM4 25348397 N/A physical interaction ComPPI
H2AX RPL26L1 25348397 N/A physical interaction ComPPI
H2AX TIMELESS 25348397 N/A physical interaction ComPPI
H2AX RPS3 25348397 N/A physical interaction ComPPI
H2AX SUPT6H 25348397 N/A physical interaction ComPPI
H2AX FGF8 25348397 N/A physical interaction ComPPI
H2AX CCDC86 25348397 N/A physical interaction ComPPI
H2AX NAP1L1 25348397 N/A physical interaction ComPPI
H2AX CTCF 25348397 N/A physical interaction ComPPI
H2AX CYP19A1 25348397 N/A physical interaction ComPPI
H2AX MACROH2A1 25348397 N/A physical interaction ComPPI
H2AX ANKHD1 25348397 N/A physical interaction ComPPI
H2AX RPS16 25348397 N/A physical interaction ComPPI
H2AX ZNF420 25348397 N/A physical interaction ComPPI
H2AX KRR1 25348397 N/A physical interaction ComPPI
H2AX CXXC1 25348397 N/A physical interaction ComPPI
H2AX ZCCHC9 25348397 N/A physical interaction ComPPI
H2AX GINS3 25348397 N/A physical interaction ComPPI
H2AX ZBTB24 25348397 N/A physical interaction ComPPI
H2AX LARP1B 25348397 N/A physical interaction ComPPI
H2AX RBM19 25348397 N/A physical interaction ComPPI
H2AX ZNF22 25348397 N/A physical interaction ComPPI
H2AX ELAVL2 25348397 N/A physical interaction ComPPI
H2AX GINS4 25348397 N/A physical interaction ComPPI
H2AX DKC1 25348397 N/A physical interaction ComPPI
H2AX RPL8 25348397 N/A physical interaction ComPPI
H2AX ZSCAN25 25348397 N/A physical interaction ComPPI
H2AX RPS9 25348397 N/A physical interaction ComPPI
H2AX RPL23A 25348397 N/A physical interaction ComPPI
H2AX RPS5 25348397 N/A physical interaction ComPPI
H2AX MRPS35 25348397 N/A physical interaction ComPPI
H2AX RPL19 25348397 N/A physical interaction ComPPI
H2AX ZNF574 25348397 N/A physical interaction ComPPI
H2AX NLRP2 15733840 24234451 25348397 colocalization,physical association pull down,imaging technique ComPPI,IntAct
H2AX UIMC1 18001824 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
H2AX NABP2 18449195 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
H2AX TDP1 19851285 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
H2AX TOP2A 20085707 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
H2AX TXNDC5 20000738 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
H2AX TAGLN2 20000738 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
H2AX EXO1 21052091 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
H2AX INO80 19014934 24234451 25348397 colocalization,association anti tag coimmunoprecipitation,confocal microscopy ComPPI,IntAct
H2AX ACTR5 19014934 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
H2AX DNMT1 22094255 24234451 25348397 27728808 colocalization,association fluorescence microscopy,confocal microscopy ComPPI,IntAct
H2AX TERF2IP 22157895 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
H2AX PALB2 22193777 24234451 24485656 25348397 colocalization fluorescence microscopy ComPPI,IntAct
H2AX MNDA 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
H2AX PPP4R3B 18614045 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
H2AX PPP4R2 18614045 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
H2AX ZC3H18 24234451 25348397 29298432 association anti tag coimmunoprecipitation ComPPI,IntAct
ILF2 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
VPS35 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB4 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CETN1 H2AX 25348397 N/A physical interaction ComPPI
PSMB3 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB11B H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATF2 H2AX 25348397 N/A physical interaction ComPPI
EEF1B2 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GINS2 H2AX 25348397 N/A physical interaction ComPPI
RNF20 H2AX 24234451 25348397 25640309 colocalization fluorescence microscopy ComPPI,IntAct
H2AX H2AX 14519663 14525934 16377563 N/A experimental interaction detection HPRD
H2AX CALM2 20000738 24234451 association anti tag coimmunoprecipitation IntAct
MKI67 H2AX 24234451 26949251 association anti tag coimmunoprecipitation IntAct
H2AX GPATCH8 24234451 30021884 physical association cross-linking study IntAct
H2AX H2BC9 24234451 30021884 physical association cross-linking study IntAct
H2AX H2BS1 24234451 30021884 physical association cross-linking study IntAct
H2AX H2BC20P 24234451 30021884 physical association cross-linking study IntAct
H2AX SCML2 25703348 27898060 N/A N/A OmniPath
BAZ1B H2AX 19092802 21326359 27898060 stimulant N/A OmniPath
H2AX MCPH1 17599047 22154951 25733871 27898060 stimulant N/A OmniPath
MAPK9 H2AX 18158901 27898060 stimulant N/A OmniPath
H2AX KAT2A 20224553 27898060 stimulant N/A OmniPath
EYA1 H2AX 19234442 19351884 20965415 27898060 inhibition N/A OmniPath
ATR H2AX 12919958 19805520 22184063 27898060 stimulant N/A OmniPath
ATM H2AX 11571274 11893489 16531125 16858402 18158901 18285803 18344987 20068231 21676867 21690091 21704408 22184063 27898060 9488723 stimulant N/A OmniPath
H2AX MDC1 12607005 14519663 15201865 16377563 16427009 18001824 18001825 19234442 20159462 21293379 21622030 21676867 26734725 27898060 stimulant N/A OmniPath
PPM1D H2AX 20101220 20118229 20460517 27898060 inhibition N/A OmniPath
H2AX TP53BP1 12447390 12607005 12697768 15364958 17024177 17145710 18001824 18001825 20075863 21317870 21566653 21623170 26734725 27898060 stimulant N/A OmniPath
PPP1CB H2AX 12926989 27898060 N/A N/A OmniPath
RNF168 H2AX 18443409 19203578 19342239 27898060 stimulant N/A OmniPath
RNF8 H2AX 18001824 18001825 22980979 26507658 27898060 stimulant N/A OmniPath
PPP1CA H2AX 12926989 27898060 N/A N/A OmniPath
EP300 H2AX 20488183 27898060 stimulant N/A OmniPath
PPP2CA H2AX 16310392 18758438 27898060 N/A N/A OmniPath
UBE2N H2AX 17709392 18077395 27898060 inhibition,stimulant N/A OmniPath
MAPK8 H2AX 17145805 19234442 20512932 27898060 stimulant N/A OmniPath
H2AX NBN 11110662 12419185 15201865 15635255 15733840 16932743 18001824 18001825 21676867 22157895 22565321 23145133 27898060 stimulant N/A OmniPath
PRKDC H2AX 10477747 10734083 12766154 12907603 14627815 15226436 15289343 15604242 15610743 15613478 15846060 15897892 16024600 16039583 16061642 16148027 16377563 16452482 16673875 16788066 16818713 16820894 16935931 17412408 17525342 17594478 17634426 17638905 17723002 18157161 18406329 18438399 18454178 18632646 18632984 18657500 18829552 18987440 19049966 19092802 19234442 19305155 19321613 20053681 20224553 20356835 20395202 20488183 20703100 20921231 20978201 21151168 21653549 21731742 21874023 22184063 23185622 23620287 23891091 24059746 24145406 24415760 25355892 25487737 25537504 25699710 25702873 25843623 26438602 27898060 9488723 stimulant N/A OmniPath
PPP4C H2AX 18614045 18758438 27898060 inhibition N/A OmniPath
PPP1CC H2AX 12926989 27898060 N/A N/A OmniPath
PPM1G H2AX 17074886 18406329 27898060 N/A N/A OmniPath
EYA3 H2AX 19234442 19351884 20965415 27898060 inhibition N/A OmniPath
PPP6C H2AX 20065038 27898060 N/A N/A OmniPath
PPP2CB H2AX 16310392 27898060 N/A N/A OmniPath

Visualization










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