GENE:ILRUN
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ILRUN |
| FullNmae | inflammation and lipid regulator with UBA-like and NBR1-like domains |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:21215 |
| EnsembleID | ENSG00000196821 |
| Uniprot | Q9H6K1 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ILRUN | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ILRUN | GO:0000407,GO:0005515,GO:0005634,GO:0005737,GO:0005813,GO:0005829,GO:0016236,GO:0016607,GO:0032480,GO:0032720,GO:0043130,GO:0043392,GO:0045087,GO:0050687,GO:1900181 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ILRUN | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | ILRUN | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | ILRUN | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | ILRUN | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | ILRUN | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | ILRUN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ILRUN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ILRUN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | ILRUN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | ILRUN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ILRUN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ILRUN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ILRUN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ILRUN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ILRUN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | ILRUN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | ILRUN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00005651EE | ILRUN | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000BE495 | ILRUN | 23592263 23622248 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS00004AC389 | ILRUN | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000075A608 | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002394F5 | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00006097A6 | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002367FA | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000585553 | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000939AF | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000011A030 | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003CC709 | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001012BC | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A9FB9 | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000383DF4 | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000057FDB8 | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000023133F | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001AFC71 | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000028BB8 | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005A8ED | ILRUN | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003575B | ILRUN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000100748 | ILRUN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | ILRUN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | ILRUN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AA464 | ILRUN | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000367985 | ILRUN | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | ILRUN | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | ILRUN | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | ILRUN | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDK2 | ILRUN | 22135298 | phosphorylation | N/A | PhosphoSite |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HSPA8 | ILRUN | 25348397 | N/A | physical interaction | ComPPI |
| HSPBP1 | ILRUN | 25348397 | N/A | physical interaction | ComPPI |
| UBE2N | ILRUN | 24234451 25260751 25348397 | ubiquitination reaction | ubiquitinase assay | ComPPI,IntAct |
| XPO1 | ILRUN | 25348397 | N/A | physical interaction | ComPPI |
| UBA1 | ILRUN | 24234451 25260751 25348397 | ubiquitination reaction | ubiquitinase assay | ComPPI,IntAct |
| SMURF1 | ILRUN | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | ILRUN | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | ILRUN | 25348397 | N/A | physical interaction | ComPPI |
| UBE2V1 | ILRUN | 24234451 25260751 25348397 | ubiquitination reaction | ubiquitinase assay | ComPPI,IntAct |
| RPSA | ILRUN | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| FBXO25 | ILRUN | 25348397 | N/A | physical interaction | ComPPI |
| MAP3K1 | ILRUN | 25348397 | N/A | physical interaction | ComPPI |
| APP | ILRUN | 25348397 | N/A | physical interaction | ComPPI |
