Gene Information gene info

GENE:ITCH

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ITCH
FullNmae itchy E3 ubiquitin protein ligase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13890
EnsembleID ENSG00000078747
Uniprot Q96J02

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ITCH autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ITCH GO:0001558,GO:0002669,GO:0002870,GO:0004842,GO:0004842,GO:0004842,GO:0004842,GO:0005515,GO:0005654,GO:0005737,GO:0005769,GO:0005829,GO:0005886,GO:0005938,GO:0006511,GO:0006511,GO:0006511,GO:0006513,GO:0006915,GO:0006954,GO:0016020,GO:0016567,GO:0016567,GO:0016874,GO:0019787,GO:0031410,GO:0031623,GO:0031901,GO:0032088,GO:0032480,GO:0032991,GO:0035519,GO:0035519,GO:0035739,GO:0043021,GO:0043066,GO:0043161,GO:0043161,GO:0043231,GO:0044389,GO:0045087,GO:0045236,GO:0045732,GO:0046329,GO:0046718,GO:0050687,GO:0051607,GO:0051865,GO:0060544,GO:0061630,GO:0061630,GO:0061630,GO:0061630,GO:0070062,GO:0070423,GO:0070534,GO:0070534,GO:0070936,GO:0070936,GO:0090085,GO:1902036,GO:1990763,GO:2000562,GO:2000646

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ITCH hsa:83737 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)
ITCH hsa:83737 path:hsa04144 Endocytosis - Homo sapiens (human)
ITCH hsa:83737 path:hsa04330 Notch signaling pathway - Homo sapiens (human)
ITCH hsa:83737 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
ITCH hsa:83737 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NUMB ITCH 10940313 11318614 12682059 16469705 16861923 17115028 17312394 18552861 18628966 20818436 20940030 21107885 21383157 23331499 26192618 stimulation,association N/A ACSN,SignaLink
ITCH YAP1 10940313 11318614 16469705 16861923 18552861 18628966 21107885 21383157 26192618 interaction type N/A ACSN
ITCH CFLAR 10940313 11318614 16469705 16861923 18552861 18628966 21107885 21383157 26192618 26972597 interaction type N/A ACSN
ITCH RIPK1 10940313 11318614 16469705 16861923 18552861 18628966 19131965 20068034 21107885 21383157 26192618 interaction type N/A ACSN
ITCH GLI1 10940313 11318614 16469705 16861923 17115028 17312394 18552861 18628966 20818436 20940030 21107885 21383157 26192618 interaction type N/A ACSN
NFE2 ITCH 11318614 23180781 physical association two hybrid,far western blotting InnateDB
ITCH SH3GL2 17038327 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
ITCH USP9X 17038327 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
UBE2L3 ITCH 17038327 17592138 23180781 ubiquitination reaction enzymatic study InnateDB
USP9X ITCH 17038327 23180781 physical association anti tag coimmunoprecipitation InnateDB
MLANA ITCH 15703212 23180781 physical association anti tag coimmunoprecipitation InnateDB
NEDD4 ITCH 15703212 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
SMAD7 ITCH 15946939 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD6 ITCH 15946939 23180781 physical association anti tag coimmunoprecipitation InnateDB
ITCH ERBB4 17463226 23180781 physical association anti tag coimmunoprecipitation,two hybrid,pull down,solid phase assay InnateDB
N4BP1 ITCH 17592138 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
ITCH TP73 17592138 23180781 physical association pull down InnateDB
TAX1BP1 ITCH 18246070 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK1 ITCH 18246070 23180781 physical association anti tag coimmunoprecipitation InnateDB
PCBP2 ITCH 19881509 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAVS ITCH 19881509 23180781 physical association anti tag coimmunoprecipitation InnateDB
UBE2D3 ITCH 19881509 23180781 ubiquitination reaction enzymatic study InnateDB
ARRB1 ITCH 17947233 23180781 physical association anti tag coimmunoprecipitation InnateDB
TOLLIP ITCH 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
ITCH ITCH 18246070 26467481 bind,up-regulates activity N/A Signor
ITCH SMAD7 15946939 19030025 21071413 23331499 stimulation N/A SignaLink,SignaLink
ITCH NOTCH1 10940313 12682059 23331499 stimulation N/A SignaLink
ITCH SMAD2 15350225 23331499 stimulation N/A SignaLink
NUMBL ITCH 16508312 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR ITCH 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ITCH 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ITCH 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ITCH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ITCH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ITCH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ITCH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ITCH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ITCH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 ITCH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ITCH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ITCH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ITCH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ITCH 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000600E6 ITCH 19074548 19096009 \N rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS00000600E6 ITCH 17242205 19074548 19096009 22473208 25416803 26621835 mrna cleavage,inhibition array technology,western blot,rna immunoprecipitation,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000005481D ITCH 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000007340 ITCH 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000076E54 ITCH 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A ITCH 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F ITCH 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C ITCH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 ITCH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F ITCH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000610EFA ITCH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 ITCH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000019F055 ITCH 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 ITCH 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 ITCH 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 ITCH 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA ITCH 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 ITCH 25416803 25815880 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
SGK3 ITCH 22135298 phosphorylation N/A PhosphoSite
FYN ITCH 22135298 phosphorylation N/A PhosphoSite
ITCH TP73 25361965 interaction type N/A PTMCode2
TP73 ITCH 25361965 interaction type N/A PTMCode2
ITCH NEDD9 25361965 interaction type N/A PTMCode2
NEDD9 ITCH 25361965 interaction type N/A PTMCode2
ITCH ARRB1 25361965 interaction type N/A PTMCode2
ARRB1 ITCH 25361965 interaction type N/A PTMCode2
ITCH CXCR4 25361965 interaction type N/A PTMCode2
CXCR4 ITCH 25361965 interaction type N/A PTMCode2
CBLC ITCH 25361965 interaction type N/A PTMCode2
ITCH CBLC 25361965 interaction type N/A PTMCode2
HGS ITCH 25361965 interaction type N/A PTMCode2
ITCH HGS 25361965 interaction type N/A PTMCode2
JUN ITCH 25361965 interaction type N/A PTMCode2
ITCH JUN 25361965 interaction type N/A PTMCode2
ATN1 ITCH 25361965 interaction type N/A PTMCode2
ITCH ATN1 25361965 interaction type N/A PTMCode2
TRPV4 ITCH 25361965 interaction type N/A PTMCode2
ITCH TRPV4 25361965 interaction type N/A PTMCode2
JUNB ITCH 25361965 interaction type N/A PTMCode2
ITCH JUNB 25361965 interaction type N/A PTMCode2
NDFIP2 ITCH 25361965 interaction type N/A PTMCode2
ITCH NDFIP2 25361965 interaction type N/A PTMCode2
SMAD7 ITCH 25361965 interaction type N/A PTMCode2
ITCH SMAD7 25361965 interaction type N/A PTMCode2
NOTCH1 ITCH 25361965 interaction type N/A PTMCode2
ITCH NOTCH1 25361965 interaction type N/A PTMCode2
RNF11 ITCH 25361965 interaction type N/A PTMCode2
ITCH RNF11 25361965 interaction type N/A PTMCode2
ARRB2 ITCH 25361965 interaction type N/A PTMCode2
ITCH ARRB2 25361965 interaction type N/A PTMCode2
NUMB ITCH 25361965 interaction type N/A PTMCode2
ITCH NUMB 25361965 interaction type N/A PTMCode2
DTX1 ITCH 25361965 interaction type N/A PTMCode2
ITCH DTX1 25361965 interaction type N/A PTMCode2
ERBB4 ITCH 25361965 interaction type N/A PTMCode2
ITCH ERBB4 25361965 interaction type N/A PTMCode2
NFE2 ITCH 25361965 interaction type N/A PTMCode2
ITCH NFE2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KPNA2 ITCH 25348397 N/A physical interaction ComPPI
NUDT21 ITCH 25348397 N/A physical interaction ComPPI
SMARCE1 ITCH 25348397 N/A physical interaction ComPPI
WASL ITCH 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SH3GLB1 ITCH 25348397 N/A physical interaction ComPPI
PCNA ITCH 25348397 N/A physical interaction ComPPI
ARRDC3 ITCH 23236378 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
SMARCC1 ITCH 25348397 N/A physical interaction ComPPI
AMOT ITCH 25348397 N/A physical interaction ComPPI
WBP2 ITCH 25348397 N/A physical interaction ComPPI
TRAF6 ITCH 25348397 N/A physical interaction ComPPI
UBE2D1 ITCH 25348397 N/A physical interaction ComPPI
RASSF5 ITCH 23538446 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TP53BP2 ITCH 24234451 25348397 25436413 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
JUNB ITCH 25348397 N/A physical interaction ComPPI
SMN1 ITCH 25348397 N/A physical interaction ComPPI
CPSF7 ITCH 25348397 N/A physical interaction ComPPI
UBE2E2 ITCH 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
LAPTM5 ITCH 25348397 N/A physical interaction ComPPI
UBE2E3 ITCH 25348397 N/A physical interaction ComPPI
PACSIN1 ITCH 25348397 N/A physical interaction ComPPI
TXNIP ITCH 25348397 N/A physical interaction ComPPI
DDX20 ITCH 25348397 N/A physical interaction ComPPI
CBL ITCH 12226085 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
ERBB4 ITCH 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,pull down,physical interaction,physical interaction ComPPI
OCLN ITCH 11782481 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
TRPV4 ITCH 14525934 17110928 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MAPK8 ITCH 25348397 N/A physical interaction ComPPI
SMAD7 ITCH 25348397 N/A physical interaction ComPPI
GRAP2 ITCH 25348397 N/A physical interaction ComPPI
NOTCH1 ITCH 12682059 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CBLC ITCH 12226085 14525934 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
GRB2 ITCH 25348397 N/A physical interaction ComPPI
NEDD9 ITCH 14525934 15051726 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
JUN ITCH 14525934 16901904 17110928 19806201 19818398 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
SMAD2 ITCH 25348397 N/A physical interaction ComPPI
NCOA1 ITCH 25348397 N/A physical interaction ComPPI
SMAD3 ITCH 25348397 N/A physical interaction ComPPI
GLI1 ITCH 20818436 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
UBE2G1 ITCH 25348397 N/A physical interaction ComPPI
UBE2D2 ITCH 25348397 N/A physical interaction ComPPI
UBE2L3 ITCH 15350225 15678106 17038327 17592138 17719543 17996703 18718449 20068034 22009753 25348397 25632008 25723849 26245901 27898060 N/A physical interaction ComPPI,OmniPath
PRKACA ITCH 25348397 N/A physical interaction ComPPI
WWP1 ITCH 25348397 N/A physical interaction ComPPI
SPART ITCH 16055720 19307600 19580544 19765186 20504295 24234451 25348397 27898060 association physical interaction,tandem affinity purification ComPPI,IntAct,OmniPath
CUL3 ITCH 25348397 N/A physical interaction ComPPI
KPNB1 ITCH 25348397 N/A physical interaction ComPPI
HGS ITCH 25348397 N/A physical interaction ComPPI
UBB ITCH 17719543 24234451 25348397 enzymatic reaction anti tag coimmunoprecipitation,physical interaction,enzymatic study ComPPI,IntAct
UBC ITCH 25348397 N/A anti tag coimmunoprecipitation,pull down,physical interaction,physical interaction ComPPI
RPS27A ITCH 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
UBA52 ITCH 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
WWP2 ITCH 25348397 N/A physical interaction ComPPI
NUMB ITCH 12682059 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CAV1 ITCH 25348397 N/A physical interaction ComPPI
MAP2K4 ITCH 25348397 N/A physical interaction ComPPI
GBA ITCH 25348397 N/A physical interaction ComPPI
IKBKB ITCH 25348397 N/A physical interaction ComPPI
CSNK2A1 ITCH 25348397 N/A physical interaction ComPPI
STAM2 ITCH 25348397 N/A physical interaction ComPPI
HNRNPL ITCH 25348397 N/A physical interaction ComPPI
CFTR ITCH 25348397 N/A physical interaction ComPPI
TRPV1 ITCH 14525934 17110928 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TP73 ITCH 14525934 15678106 17592138 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,phage display,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PABPC1 ITCH 25348397 N/A physical interaction ComPPI
EWSR1 ITCH 25348397 N/A physical interaction ComPPI
UBA6 ITCH 25348397 N/A physical interaction ComPPI
ARRB1 ITCH 25348397 N/A physical interaction ComPPI
USP13 ITCH 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DVL1 ITCH 25348397 N/A physical interaction ComPPI
DVL2 ITCH 25348397 N/A physical interaction ComPPI
ARRB2 ITCH 25348397 N/A physical interaction ComPPI
MDM2 ITCH 21093410 25348397 26025930 27898060 N/A physical interaction ComPPI,OmniPath
ITSN1 ITCH 25348397 N/A physical interaction ComPPI
SNX9 ITCH 20491914 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
SNX18 ITCH 20491914 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BIN1 ITCH 25348397 N/A physical interaction ComPPI
ADRB2 ITCH 23236378 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EGFR ITCH 25348397 N/A physical interaction ComPPI
SCNN1A ITCH 25348397 N/A physical interaction ComPPI
SCNN1B ITCH 25348397 N/A physical interaction ComPPI
SFN ITCH 25348397 N/A physical interaction,tandem affinity purification ComPPI
HTT ITCH 24865853 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CDC34 ITCH 25348397 N/A physical interaction ComPPI
KLF10 ITCH 25348397 N/A physical interaction ComPPI
YAP1 ITCH 25348397 N/A physical interaction ComPPI
URI1 ITCH 25348397 N/A physical interaction ComPPI
POLR2E ITCH 25348397 N/A physical interaction ComPPI
POLR2A ITCH 14525934 16055720 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RASSF1 ITCH 25348397 N/A physical interaction ComPPI
HDAC6 ITCH 25348397 N/A physical interaction ComPPI
DTX1 ITCH 14525934 17028573 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique,in vivo ComPPI,HPRD,IntAct
ITCH RNF11 14525934 14559117 19131965 20676133 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
ITCH TRPC4 14525934 17110928 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ITCH SGK3 14525934 16888620 24234451 25348397 phosphorylation reaction,colocalization,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,protein kinase assay,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
ITCH CPSF6 25348397 N/A physical interaction,in vitro,in vivo ComPPI
ITCH RIPK1 14525934 19131965 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
ITCH ATN1 14525934 25348397 9647693 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
ITCH CXCR4 25348397 N/A physical interaction ComPPI
ITCH TP53 16908849 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ITCH N4BP1 17592138 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
ITCH USP9X 17038327 19341794 25348397 26508657 27898060 N/A physical interaction ComPPI,OmniPath
ITCH FYN 25348397 N/A physical interaction ComPPI
ITCH MLANA 20491914 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
ITCH UBAP2L 25348397 N/A physical interaction ComPPI
ITCH TP63 16908849 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ITCH BID 25348397 N/A physical interaction ComPPI
ITCH NDFIP2 14525934 15252135 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
ITCH CYLD 22057290 23782702 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
ITCH TNFRSF10B 25348397 N/A physical interaction ComPPI
ITCH LATS1 21212414 21383157 23564455 24107629 25348397 27898060 N/A physical interaction ComPPI,OmniPath
ITCH TOLLIP 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ITCH ARRDC1 21191027 23236378 23886940 24234451 25348397 26186194 27898060 physical association two hybrid,physical interaction ComPPI,IntAct,OmniPath
ITCH TGFBR1 25348397 N/A physical interaction ComPPI
ITCH ELAVL1 25348397 N/A physical interaction ComPPI
ITCH TAX1BP1 25348397 N/A physical interaction ComPPI
ITCH STAM 25348397 N/A physical interaction ComPPI
ITCH MAVS 25348397 N/A physical interaction ComPPI
ITCH PCBP2 25348397 N/A physical interaction ComPPI
ITCH ARHGEF7 17652093 25348397 26613292 27898060 N/A physical interaction ComPPI,OmniPath
ITCH DVL1P1 25348397 N/A physical interaction ComPPI
ITCH DVL3 25348397 N/A physical interaction ComPPI
ITCH USP12 22778262 25348397 26811477 27898060 N/A physical interaction ComPPI,OmniPath
ITCH WDR48 25348397 N/A physical interaction ComPPI
ITCH BECN1 25348397 N/A physical interaction ComPPI
ITCH LITAF 21326863 25348397 25963657 27898060 N/A physical interaction ComPPI,OmniPath
ITCH GNAI2 25348397 N/A physical interaction ComPPI
ITCH UBE2E1 25348397 N/A physical interaction ComPPI
ITCH UBE2J2 25348397 N/A physical interaction ComPPI
ITCH UBE2K 25348397 N/A physical interaction ComPPI
ITCH POU5F1 23255053 25348397 27898060 N/A physical interaction ComPPI,OmniPath
ITCH MGRN1 25348397 N/A physical interaction ComPPI
ITCH ARRDC4 23236378 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ITCH FBXL15 21572392 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ITCH UBE2D3 25348397 N/A physical interaction ComPPI
ITCH ARID1A 25348397 N/A physical interaction ComPPI
ITCH POLR2B 25348397 N/A physical interaction ComPPI
ITCH POLR2C 25348397 N/A physical interaction ComPPI
ITCH SMARCC2 25348397 N/A physical interaction ComPPI
ITCH DAZAP1 25348397 N/A physical interaction ComPPI
ITCH RPAP2 25348397 N/A physical interaction ComPPI
ITCH HNRNPUL1 25348397 N/A physical interaction ComPPI
ITCH SF1 25348397 N/A physical interaction ComPPI
ITCH RPAP3 25348397 N/A physical interaction ComPPI
ITCH UBAP2 25348397 N/A physical interaction ComPPI
ITCH WWOX 25348397 N/A physical interaction ComPPI
ITCH DTX3L 25348397 N/A physical interaction ComPPI
ITCH SMAD6 25348397 N/A physical interaction ComPPI
ITCH ATXN3 25348397 N/A physical interaction ComPPI
ITCH PTCH1 25348397 N/A physical interaction ComPPI
ITCH GSN 25348397 N/A physical interaction ComPPI
ITCH GGA3 25348397 N/A physical interaction ComPPI
ITCH FAM189B 25348397 N/A physical interaction ComPPI
ITCH TMEM171 25348397 N/A physical interaction ComPPI
ITCH PLEKHB2 25348397 N/A physical interaction ComPPI
ITCH FAM189A2 25348397 N/A physical interaction ComPPI
ITCH WBP1 25348397 N/A physical interaction ComPPI
ITCH TMEM255A 25348397 N/A physical interaction ComPPI
ITCH TMEM92 25348397 N/A physical interaction ComPPI
ITCH LDLRAD4 25348397 N/A physical interaction ComPPI
ITCH NDFIP1 25348397 N/A physical interaction ComPPI
ITCH MAP3K7 25348397 N/A physical interaction ComPPI
ITCH TAB1 25348397 25714464 27898060 N/A physical interaction ComPPI,OmniPath
ITCH GLIS3 25348397 N/A physical interaction ComPPI
ITCH PACSIN2 25348397 N/A physical interaction ComPPI
ITCH PDCD6IP 25348397 N/A physical interaction ComPPI
ITCH COL18A1 25348397 N/A physical interaction ComPPI
ITCH LRRK2 25348397 N/A physical interaction ComPPI
ITCH SCAMP3 25348397 N/A physical interaction ComPPI
ITCH SLC1A5 25348397 N/A physical interaction ComPPI
ITCH SLC3A2 25348397 N/A physical interaction ComPPI
ITCH UBA1 25348397 N/A physical interaction ComPPI
ITCH USP5 25348397 N/A physical interaction ComPPI
ITCH GEMIN8 25348397 N/A physical interaction ComPPI
ITCH SARAF 25348397 N/A physical interaction ComPPI
ITCH ILDR1 25348397 N/A physical interaction ComPPI
ITCH UBE2M 25348397 N/A physical interaction ComPPI
ITCH MARVELD2 25348397 N/A physical interaction ComPPI
ITCH MTSS1 25348397 N/A physical interaction ComPPI
ITCH SH3GL1 25348397 N/A physical interaction ComPPI
ITCH PI4K2A 23146885 24234451 25348397 colocalization,physical association nuclear magnetic resonance,pull down,fluorescence microscopy ComPPI,IntAct
ITCH LRRK1 24234451 24947832 25348397 N/A protein array ComPPI,IntAct
SH3GL2 ITCH 14525934 14684745 17038327 24234451 25348397 26613292 27898060 ubiquitination reaction,colocalization,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
CFLAR ITCH 25348397 N/A physical interaction ComPPI
NFE2 ITCH 11318614 18718448 25348397 27898060 N/A physical interaction ComPPI,OmniPath
ECH1 ITCH 25348397 N/A anti tag coimmunoprecipitation ComPPI
TMEM51 ITCH 25348397 N/A physical interaction ComPPI
ITCH ITCH 11526121 14525934 N/A experimental interaction detection HPRD
FYN ITCH 16387660 17053785 27898060 N/A N/A OmniPath
NUMB ITCH 12682059 18628966 20818436 27898060 stimulant N/A OmniPath
ITCH TRPV4 17110928 20650893 27898060 inhibition,stimulant N/A OmniPath
ARRB1 ITCH 17947233 18544533 27898060 N/A N/A OmniPath
ITCH TNFAIP3 18246070 27898060 stimulant N/A OmniPath
YAP1 ITCH 19788416 27898060 inhibition N/A OmniPath
MAVS ITCH 19881509 27898060 N/A N/A OmniPath
ITCH TP63 16861923 16908849 20855944 22935697 23370280 25485500 27898060 inhibition N/A OmniPath
ITCH SMAD2 15350225 27898060 stimulant N/A OmniPath
ITCH GLI1 17115028 20818436 27898060 inhibition N/A OmniPath
ITCH NOTCH1 10940313 12682059 1268206 27898060 inhibition,stimulant N/A OmniPath
RIPK1 ITCH 18246070 19131965 27898060 N/A N/A OmniPath
ITCH TP73 11278685 15678106 17110958 17592138 19788416 20855944 27898060 inhibition,stimulant N/A OmniPath
ITCH CFLAR 18559494 18786561 19090833 19808964 21474069 27898060 inhibition N/A OmniPath
MAPK8 ITCH 16446428 16469705 27898060 stimulant N/A OmniPath
CSK ITCH 16888620 27898060 inhibition N/A OmniPath
ITCH SMAD7 15946939 1594694 19030025 22773947 27898060 inhibition,stimulant N/A OmniPath
ITCH TNIP2 16469705 27898060 inhibition N/A OmniPath
NUMBL ITCH 16508312 27898060 stimulant N/A OmniPath
RNF11 ITCH 14559117 19131965 20676133 22507528 27898060 stimulant N/A OmniPath
TOLLIP ITCH 21903422 27898060 N/A N/A OmniPath
ITCH DTX1 17028573 18628966 27898060 inhibition N/A OmniPath
SGK3 ITCH 16888620 27898060 N/A N/A OmniPath

Visualization